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Ned Tijdschr Geneeskd ; 155: A3149, 2011.
Artículo en Holandés | MEDLINE | ID: mdl-21586183

RESUMEN

BACKGROUND: Persistent polyclonal B-cell lymphocytosis (PPBL) is a benign condition associated with smoking. CASE REPORT: A 42-year-old woman was referred to an internist because of an abnormal blood test outcome identified during routine sampling. She had no symptoms; she had smoked for thirty pack years. Physical examination revealed no abnormalities. Laboratory analysis showed absolute lymphocytosis. A blood smear identified binuclear ('buttock') cells. The diagnosis of persistent polyclonal B-cell lymphocytosis (PPBL) was made, with nicotine abuse as the probable cause. The patient was advised to quit smoking. CONCLUSION: Polyclonal B-cell lymphocytosis is a benign condition that is characterised by: (a) polyclonal increase of B-lymphocytes in peripheral blood; (b) the presence of binuclear lymphocytes (buttock cells) in microscopic differentiation; (c) polyclonal increase in IgM. Recognition is important for the prevention of unnecessary diagnostic testing.


Asunto(s)
Linfocitos B/patología , Linfocitosis/etiología , Linfocitosis/patología , Fumar/efectos adversos , Adulto , Femenino , Humanos , Cese del Hábito de Fumar
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