1.
Biomed Pharmacother
; 64(9): 624-6, 2010 Nov.
Artículo
en Inglés
| MEDLINE
| ID: mdl-20888176
RESUMEN
Trypanocidal activity of a number of lipophilic diamines and amino alcohols was evaluated in vitro against Trypanosoma cruzi blood stream forms. Several of the studied compounds showed inhibition of T. cruzi growth. The most active ones were compounds 3, 4 and 5 with a IC50 of 31.2 µg/mL, activity similar to the reference drug crystal violet.