RESUMEN
The varicella-zoster virus (VZV), a member of the Herpesviridae family (HHV-3), is the pathogen responsible for causing herpes zoster, the skin eruption known as shingles. This report describes a rare presentation of herpes zoster involving cutaneous vasculitis in the unilateral upper extremity in an immunocompetent patient. Histologic evaluation confirmed a diagnosis of leukocytoclastic vasculitis and yielded a positive VZV immunoperoxidase stain. An approach to histologic evaluation of this case is discussed.
RESUMEN
The diagnosis of scabies infestation is straightforward in cases where mite parts are largely visible; however, mites are often not captured in a specimen's planes of section. Polariscopic examination is a fast and simple adjunctive diagnostic tool to light microscopy. We describe the unique polariscopic findings in scabies infestation. Two cases of crusted scabies and eight cases of typical scabies were subjected to polariscopic examination. Diagnostic mite parts were visualized in at least one section in all cases. Attached and detached spines as well as scybala (fecal material) are polarizable. Specifically, spines show a polarizable outer sheath with dark central core while scybala show peripherally concentrated, stippled birefringence. Similar stippled birefringence is visible within the gut of some mites whereas significant birefringence is not appreciated in other mite parts. These results suggest that polariscopic examination is a helpful clue in the diagnosis of scabies infestation, especially in cases where the body of the mite is not visualized.
Asunto(s)
Dermoscopía/métodos , Microscopía de Polarización/métodos , Prurito/patología , Prurito/parasitología , Escabiosis/diagnóstico , Animales , Birrefringencia , Heces , Femenino , Folículo Piloso/parasitología , Folículo Piloso/patología , Humanos , Masculino , Ácaros/crecimiento & desarrollo , Ácaros/ultraestructura , Estudios RetrospectivosAsunto(s)
Eritema/patología , Ganglios Linfáticos/patología , Sarcoma de Células Pequeñas/complicaciones , Neoplasias de los Tejidos Blandos/complicaciones , Neoplasias de los Tejidos Blandos/patología , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico , Quimioradioterapia , Eritema/complicaciones , Humanos , Hiperplasia/complicaciones , Hiperplasia/patología , Imagen por Resonancia Magnética , Masculino , Persona de Mediana Edad , Sarcoma de Células Pequeñas/secundario , Sarcoma de Células Pequeñas/terapia , Neoplasias de los Tejidos Blandos/terapiaRESUMEN
There is no universally accepted treatment regimen and no evidence-based literature to guide management of hypertrophic scars. This article summarizes the existing literature regarding topical treatments such as silicone gel sheeting and ointment, onion extract, vitamin E, pressure garment therapy, massage therapy, and topical imiquimod 5% cream in the management of hypertrophic scars.
