Treatment modalities and risk factors associated with refractory neurosensory disturbances of the inferior alveolar nerve following oral surgery: a multicentre retrospective study.

Little research has been conducted into hypoesthesia, and no studies have elucidated the risk factors for refractory hypoesthesia and compared treatment modalities. The purpose of this multicentre retrospective cohort study was to investigate the relationships between various risk factors, treatment modalities, and refractory hypoesthesia. Risk factors for refractory hypoesthesia after oral surgery were evaluated using univariate and multivariate analysis. To minimize the selection bias associated with a retrospective data analysis, a propensity score analysis was performed between the medication and non-medication groups (65 sites in each group). Moderate or severe hypoesthesia (odds ratio 13.42) and no or late administration of ATP/vitamin B12 (odds ratio 2.28) were significantly associated with refractory hypoesthesia. In the propensity score analysis, the incidence rate of refractory hypoesthesia in the medication group was lower than that in the non-medication group (P<0.001). This study demonstrated the multivariate relationships between various risk factors, treatment modalities, and refractory hypoesthesia. Moderate or severe hypoesthesia and no or late administration of ATP/vitamin B12 were significantly associated with refractory hypoesthesia. Therefore, clinicians should consider these risk factors and initiate early oral administration of ATP/vitamin B12 in cases of hypoesthesia.

Electron energy-loss spectroscopy study of amorphization process of graphite bombarded with hydrogen ions and energetic electrons at low temperatures.

Structural change of graphite bombarded with hydrogen ions as well as energetic electrons is investigated mainly by the EELS (electron energy-loss spectroscopy) technique, with a focus on the formation of diamond-like amorphous (DLA) phase at low temperatures. The chemical effects of hydrogen ions on the amorphization process are examined by comparing the results obtained by hydrogen-ion bombardment with those obtained by electron bombardment. The critical temperatures for the formation of DLA phase during hydrogen-ion and electron bombardments are determined. Finally, a model of the amorphization process of graphite during ion-bombardment is presented.

Predicting to 9-month performance of premature infants.

This article identifies variables found to be predictive of sensorimotor and psychosocial performance in infants at 9 months adjusted age. The subjects were 102 infants with a birth weight of less than 1,500 g, who were participants in an early intervention project. Multiple regression analyses disclosed that poor 9-month performance was related to a lack of special Neonatal Intensive Care Unit (NICU) intervention, to minority group membership, to birth weight, and to performance on selected tests administered in the NICU. We present implications for the early prediction of handicapping conditions and for further research.