New Iron Oxide Nanoparticles Catechol-Grafted with Bis(amidoxime)s for Uranium(VI) Depletion of Aqueous Solution.

Environmental pollution caused by heavy metals constitutes a serious public health problem. In the case of uranium depletion, amidoxime groups are important because of their high affinity for uranium(VI). New series of bis(amidoxime)s with catechol-derived anchor groups were tested (b-AMD-1 and b-AMD-2). The catechol groups were designed to bind to the surface of maghemite nanoparticles (MNPs), and two nanohybrid devices MNP-b-AMD-1 and MNP-b-AMD-2 were obtained. This strategy makes for efficient removal of U(VI) via its complexation with the bis(amidoxime)s (b-AMD) and also its extraction from aqueous solution by magnetic harvesting of the MNPs. The assynthesized and b-AMD-grafted MNPs were characterized by several techniques: X-ray diffraction (XRD), high-angle annular dark-field (HAADF) scanning transmission electron microscopy (STEM), X-ray photoelectron spectrophotometry (XPS), thermal analysis (TG/DTA) and Fourier transform infrared spectroscopy (FTIR). Sorption tests were run at pH 6.5, which corresponds to the highest affinity and selectivity of b-AMD for U(VI). After magnetic separation, the chelation ability and the selectivity of MNP-b-AMD-1 and MNP-b-AMD-2 towards U(VI) were evaluated by measuring the residual U(VI) concentration in the supernatant by inductively coupled plasma-mass spectrometry (ICP-MS). The data were plotted according to the Langmuir and Freundlich isotherms; the maximal sorption capacity (qmax) was 29 and 60 mg U g-1 for MNP-b-AMD-1 and MNP-b-AMD-2, respectively. This confirms that bis(amidoxime) groups are good candidates for uranium depletion of aqueous solution.

Total synthesis of norbadione A.

A short, convergent synthesis of the mushroom pigment norbadione A is described. The construction of an appropriately substituted naphtholactone intermediate involved a regioselective Diels-Alder reaction between a bis(triisopropylsilyloxy)diene and 2,6-dichlorobenzo-1,4-quinone. A double Suzuki-Miyaura cross-coupling between a diboronate and two identical enol triflates was another key feature of the synthesis.