RESUMEN
The Yellow River water of an urban area located in the middle and lower reaches of the Yellow River was taken as the research objectï¼ in which the seasonal and along-range distribution of total culturable bacteriaï¼ typical antibiotic resistant bacteria ï¼amoxicillin resistant bacteria and sulfamethoxazole-resistant bacteriaï¼ï¼ and their corresponding typical resistance genes ï¼»ß-lactam resistance gene ï¼blaCTX-Mï¼ and sulfamamide resistance genes ï¼sulI and sulâ ¡ï¼ï¼ as well as intâ 1 were investigated. The results showed that the total culturable bacteriaï¼ ß-lactam-resistant bacteria and sulfonamide-resistant bacteria in the Yellow River Basin were significantly affected by temperature and human activities. The composition and quantity of their genera had obvious spatiotemporal distribution characteristicsï¼ in which Bacillus and Pseudomonas were dominant in the composition and number of bacteria. The abundance of resistance genes decreased with the decrease in temperature. The proportion of ß-lactam resistance genes in the total genes was higher than that of sulfanilamide genesï¼ and sulI was the dominant gene in sulfanilamide genes. Correlation analysis showed that class â integron played an important role in accelerating the spread of resistance genes. This study offers insight into the status quo of water resistance pollution in the Yellow River and provides theoretical support for the risk assessment of resistance genes in the middle and lower reaches of the Yellow River Basin.