The combination of coculture and selective assisted hatching: results from their clinical application.

OBJECTIVE: To establish pregnancies using a combination of coculture and selective assisted hatching. DESIGN: Clinical application for a selected group of patients. Not a controlled study. SETTING: Private infertility practice. PATIENTS: Women with high basal FSH levels, ovulatory disorders, and multiple failed IVF attempts. MAIN OUTCOME MEASURES: Pregnancy and implantation rates. RESULTS: Of the 95 patients who had coculture and selective assisted hatching, 45 (47.0%) have an ongoing pregnancy with a 23.0% implantation rate. CONCLUSION: The combination of coculture and assisted hatching produced acceptable pregnancy and implantation rates within the selected patient population.