Does subjective socioeconomic status moderate the effect of basic psychological need satisfaction on undergraduates' affective forecasting?

Affective forecasts are people's predictions of their future feelings in response to future events. In this study, based on the self-determination theory (SDT), we examined whether satisfying basic psychological needs influence undergraduates' affective forecasting and the moderating role of subjective socioeconomic status (SES). With a total of 423 undergraduate participants (177 males, 246 females), through one pilot study and three experiments, we first manipulated participants' basic psychological need satisfaction, i.e., autonomy need satisfaction (study 1), competence need satisfaction (study 2), and relatedness need satisfaction (study 3), then we asked low-SES and high-SES participants, respectively, to predict the pleasantness of a particular new product and evaluated the actual experience with the product. Results showed that the effect of basic psychological need on affective forecasting was not significant. When the need for autonomy need and competence need was satisfied, the impact bias was greater for the high SES than the low SES. Conversely, when the relatedness need was satisfied, the impact bias was greater for the low SES than the high SES. In conclusion, subjective SES moderated the influence of basic psychological needs satisfaction on increasing the impact bias in affective forecasting.

The Impact of Childhood Socioeconomic Status on Adolescents' Risk Behaviors: The Role of Physiological and Psychological Threats.

Adolescence is a period of high levels of risk behavior. The present research aims to examine the influences of childhood socioeconomic status (SES) on risk behaviors in gain or loss domains among adolescents and the roles of threats in this effect. In experiment 1, a total of 107 adolescents (Mage = 14.80; SDage = 1.15) were asked to complete the childhood socioeconomic status scale before they took part in a risk behavior task under the gain and loss situation. A total of 149 adolescents (Mage = 14.24; SDage = 1.11) in experiment 2a and 139 adolescents (Mage = 13.88; SDage = 1.09) in experiment 2b completed the childhood socioeconomic status scale before they took part in a risk behavior task under the gain and loss situation under physiological threats and psychological threats, respectively. The results showed that high-childhood-SES adolescents tend to take more risks than low-childhood-SES adolescents in the gain domain, while low-childhood-SES adolescents tend to take more risks than high-childhood-SES adolescents in the loss domain. Threats amplified the impact of childhood socioeconomic status on adolescents' risk behaviors in the gain and loss domains. When a physiological threat or psychological threat was primed, compared to the control group, in the gain situation, the extent to which high-childhood-SES adolescents showed greater risk seeking than low-childhood-SES adolescents became larger; in the loss domain, the extent to which low-childhood-SES adolescents showed greater risk seeking than high-childhood-SES adolescents became larger.

Job Mobility and Subjective Well-Being among New-Generation Migrant Workers in China: The Mediating Role of Interpersonal Trust.

New-generation migrant workers refers to those born in 1980 or thereafter, who become the majority of rural-urban migrants. New-generation migrant workers in Chinese cities are struggling with a lack of urban resources, which may lead to low well-being. On the basis of a questionnaire survey of 203 new-generation migrant workers, we used a multiple regression analysis to study new-generation migrant workers' well-being and the mechanism underlying the effect of job mobility on well-being. The job mobility scale, interpersonal trust scale, and Affect Balance Scale were used. Results showed that job mobility was positively correlated with new-generation migrant workers' subjective well-being and interpersonal trust, and interpersonal trust was positively correlated with subjective well-being. Interpersonal trust mediated the effect of job mobility on subjective well-being. In conclusion, job mobility can bring some benefits to new-generation migrant workers, that is, job mobility may increase their subjective well-being by increasing their interpersonal trust.

The effect of chronic regulatory focus and social comparison on undergraduates' intertemporal choices under gain-loss frame.

Intertemporal choice refers to decisions involving tradeoffs among costs and benefits occurred at different times. To investigate whether college students' intertemporal decision making under the gain and loss frames is affected by their chronic regulatory focus. Currently, experiment 1 investigated the influence of college students' chronic regulatory focus on intertemporal decision making under the gain and loss frames, and experiment 2 further explored the moderating effect of social comparison (i.e., upward or downward social comparison) during this process. The results showed that intertemporal choices of participants with promotive focus was no significant difference between the gain frame and loss frame, while college students with preventive focus chose later and larger rewards more in loss frame than in gain frame. Social comparison moderated the effects of the chronic regulatory focus on college students' intertemporal choice in gain and loss frames. The upward comparison enhanced the influence of regulatory focus on intertemporal choice in the gain and loss frames, while the downward comparison weakened it.

Simulation of the Urban Space Thermal Environment Based on Computational Fluid Dynamics: A Comprehensive Review.

Rapid urbanization has made urban space thermal environment (USTE) problems increasingly prominent. USTE research is important for improving urban ecological environment and building energy consumption. Most studies on USTE research progress have focused on meteorological observations and remote sensing methods, and few studies on USTE are based on computational fluid dynamics (CFD). During the past two decades, with the increasing applications of CFD in USTE research, comprehensively summarizing the phased results have become necessary tasks. This paper analyzes the current research status of CFD-based USTE simulation from six perspectives. First, we summarize the current research status of USTE simulation with CFD models that integrate ground observations and remote sensing technology. Second, we define and classify the spatial scope of CFD-based USTE simulations at different scales. Third, we systematically analyze the quantitative relationships among urban land type, the underlying surface structure, water bodies, green space and the corresponding changes in CFD-based USTE simulations. Fourth, we quantitatively analyze the impact of anthropogenic heat in CFD-based USTE simulations. Fifth, we summarize the corresponding USTE mitigation measures and methods based on the CFD simulation results. Finally, the outlooks and the existing problems in current research on CFD simulations of the USTE are analyzed.

The experience of palliative care among older Chinese people in nursing homes: A scoping review.

OBJECTIVE: To identify the gaps in understanding the experience of older Chinese people receiving palliative care in nursing homes. DESIGN: A nine-step scoping review methodology was used to search for relevant literature. METHODS: Sixteen databases were searched for relevant studies published in English from January 1990 to August 2019. The grey literature was searched for relevant theses pertaining to the topic. RESULTS: A total of 18 studies from the United States (n = 2), mainland China (n = 1), Hong Kong (n = 13), Taiwan (n = 2) and one thesis from Hong Kong were included in the final analysis. The findings were categorised into four themes: (1) advance care planning preferences; (2) decision-making process related to palliative care; (3) palliative care experiences and barriers; and (4) practice to improve palliative care. CONCLUSIONS: Given the distinctive experiences of older Chinese residents in nursing homes when faced with death and dying, cultural beliefs strongly influenced their attitudes and behaviours in receiving end-of-life care. As Chinese immigrants have become a major ethnic group in western countries, there is benefit in recognising that older Chinese people living in nursing homes and needing palliative care will face specific challenges. Culturally appropriate interventions to address older Chinese people's existential stress, grief related to loss, communication and dietary requirements, and other barriers should be developed and implemented.

Apatinib Combined with Local Irradiation Leads to Systemic Tumor Control via Reversal of Immunosuppressive Tumor Microenvironment in Lung Cancer.

PURPOSE: This study aimed to investigate the potential systemic antitumor effects of stereotactic ablative radiotherapy (SABR) and apatinib (a novel vascular endothelial growth factor receptor 2 inhibitor) via reversing the immunosuppressive tumor microenvironment for lung carcinoma. MATERIALS AND METHODS: Lewis lung cancer cells were injected into C57BL/6 mice in the left hindlimb (primary tumor; irradiated) and in the right flank (secondary tumor; nonirradiated). When both tumors grew to the touchable size, mice were randomly divided into eight treatment groups. These groups received normal saline or three distinct doses of apatinib (50 mg/kg, 150 mg/kg, and 200 mg/kg) daily for 7 days, in combination with a single dose of 15 Gy radiotherapy or not to the primary tumor. The further tumor growth/regression of mice were followed and observed. RESULTS: For the single 15 Gy modality, tumor growth delay could only be observed at the primary tumor. When combining SABR and apatinib 200 mg/kg, significant retardation of both primary and secondary tumor growth could be observed, indicated an abscopal effect was induced. Mechanism analysis suggested that programmed death-ligand 1 expression increased with SABR was counteract by additional apatinib therapy. Furthermore, when apatinib was combined with SABR, the composition of immune cells could be changed. More importantly, this two-pronged approach evoked tumor antigen-specific immune responses and the mice were resistant to another tumor rechallenge, finally, long-term survival was improved. CONCLUSION: Our results suggested that the tumor microenvironment could be managed with apatinib, which was effective in eliciting an abscopal effect induced by SABR.

Safety and efficacy of PD-1 blockade-activated multiple antigen-specific cellular therapy alone or in combination with apatinib in patients with advanced solid tumors: a pooled analysis of two prospective trials.

BACKGROUND: The lethal effects of multiple antigen-specific cellular therapy (MASCT) may be enhanced by blocking PD-1 in vitro and vascular endothelial growth factor receptor 2 inhibitor (apatinib). We analyzed the pooled data from our phase I/II trials to determine the toxicity and efficacy of PD-1 blockade (SHR-1210)-activated MASCT (aMASCT) alone or in combination with apatinib in advanced solid tumors. METHODS: Patients with advanced solid tumors received aMASCT alone (n = 32) or aMASCT plus apatinib (500 mg q.d., n = 38) after standard treatment. The safety profile was the primary end point. The secondary end points were antitumor response, progression-free survival (PFS), and overall survival (OS). The circulating T cells were quantified before and after aMASCT infusion. RESULTS: Treatment-related adverse events (AEs) occurred in 18/32 (56.3%) and 25/38 (65.8%) patients in the aMASCT and aMASCT plus apatinib groups, respectively. No serious AEs were reported, and apatinib did not increase immunotherapy-related toxicity. The objective response rate (34.2% and 18.8%) and PFS (median 6.0 and 4.5 months, P = 0.002) were improved in the aMASCT plus apatinib group compared with the aMASCT group; however, the OS was not improved (median 10.0 and 8.2 months, P = 0.098). Multivariate analyses indicated that two or more cycles of aMASCT treatment was an independent and favorable prognostic factor of PFS and OS. The circulating T cells increased and Tregs decreased in both groups after one cycle of aMASCT treatment. CONCLUSIONS: Treatment with aMASCT plus apatinib was safe and effective for the management of advanced solid tumors.

A seminaphthorhodafluor-based near-infrared fluorescent probe for hydrazine and its bioimaging in living systems.

Hydrazine (N2H4) has been classified as a potential carcinogen with its high toxicity, which can be readily absorbed through the skin or via breathing directly. Although some fluorescent probes have been developed for imaging of N2H4, very little can be used for imaging of N2H4 in vivo because of its short emission wavelength. In this study, a new colorimetric and near-infrared (NIR) fluorescent probe CF-1 based on a seminaphthorhodafluor dye was successfully designed and used for hydrazine determination. Upon reaction with N2H4, probe CF-1 showed obvious off-on NIR emission spectrum centered at 657 nm, as well as a distinct color change that can be distinguished by the naked eye. The results of fluorescence spectrum experiments indicated that probe CF-1 has high selectivity and low detection limitation (40.6 nM in the solution). Probe CF-1 has low cytotoxicity and was applied to imaging hydrazine in mitochondria of HeLa cells and in zebrafish.

Does the Use of WeChat Lead to Subjective Well-Being?: The Effect of Use Intensity and Motivations.

Recently, WeChat has been widely used in China. The positive and negative effects of WeChat on users have received attention from researchers gradually. Using the questionnaire method, we recruited 339 undergraduates and graduates as participants, and tested the effects of WeChat on their subjective well-being (SWB) in terms of intensity. In addition, we confirmed the mediating effects of WeChat with respect to motivation. The results showed that the participants' WeChat use intensity was at a mid-level, 85.3 percent of them spending no more than 2 hours on WeChat every day. Furthermore, there have been no demographic differences in the variables of gender, place of residence, or grade. Participants' WeChat use intensity can significantly predict their use motivation and life satisfaction, and intrinsic use motivation was the mediator between the use intensity and SWB, while the other three types of motivation (external, introjection, and identification) cannot predict SWB significantly. The user's ultimate emotional experience is primarily derived from why and how they use it. We also tested whether the use motivation can be shaped.

The migration law of overlay rock and coal in deeply inclined coal seam with fully mechanized top coal caving.

In a mine area, some environment geotechnics problems always occure, induced by mined-out region such as the subsidence and cracks at ground level, deformation and destruction of buildings, landslides destruction of water resources and the ecological environment. In order to research the migration of surrounding rock and coal in steeply inclined super high seams which used fully mechanized top coal caving, a working face of a certain mine was made as an example, analyzed the migration law of the overlay rock and coal under different caving ratio of fully mechanized top coal caving with numerical simulation analysis. The results suggest that the laws of overlay rock deformation caused by deeply inclined coal seam were different from horizontal coal seam. On the inclined direction, with an increase of dip angle and caving ratio, the vertical displacement of overlay rock and coal became greater, the asymmetric phenomenon of vertical displacement became obvious. On the trend direction, active region and transition region in goaf became smaller along with the increase of mining and caving ratio. On the contrary, the stable region area became greater. Therefore, there was an essential difference between the mechanism of surface movement deformation with deeply inclined coal seam and that with horizontal coal seam.