RESUMEN
This article reports on the treatment of jaw cysts using a new bone substitute material. Ostim is a nanocrystalline, phase-pure hydroxylapatite which is manufactured in an aqueous suspension and then concentrated to form a white paste with a 35% content. The material is applied directly into the bone cavity using a syringe and, due to its paste consistency, produces uniform surface contact with the walls of the bone cavity. The material is fully resorbed and ensures rapid bony regeneration of jaw defects with no complications during the healing process. The results of 44 applications were described.
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Sustitutos de Huesos , Sistemas de Liberación de Medicamentos , Durapatita , Quistes Maxilomandibulares/cirugía , Nanopartículas , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Regeneración Ósea/fisiología , Femenino , Estudios de Seguimiento , Humanos , Quistes Maxilomandibulares/diagnóstico por imagen , Masculino , Enfermedades Mandibulares/diagnóstico por imagen , Enfermedades Mandibulares/cirugía , Persona de Mediana Edad , Quistes Odontogénicos/diagnóstico por imagen , Quistes Odontogénicos/cirugía , Complicaciones Posoperatorias/diagnóstico por imagen , Radiografía PanorámicaRESUMEN
BACKGROUND: To determine the temperature- and pain thresholds of patients (n=20) who had undergone mandibular sagittal split osteotomy (MSSO), we developed a specific thermal probe to evaluate the neurosensory disturbances of the inferior alveolar nerve under prospective study conditions. METHODS: Measurements were performed prior to surgery and postoperatively up to 6 months. Thermal probe test results were compared to the results of the usual two-point discrimination test and the sharp/blunt test. Furthermore we took the subjective neurosensory perception of each patient into account. RESULTS: With focus on our newly developed thermal probe and under comparison with the preoperative results, the postoperative neurosensory tests revealed increased thresholds of up to 12.7 degrees C. Between 3 and 6 months postoperatively, quantitative resensitization could be evaluated. In contrast, the usual testing methods were not accurate enough to give valuable significant data within 3 and 6 months postoperatively. Our evaluation could also show that after 6 months thermal thresholds were up 1.5 degrees C as compared with the preoperative status. CONCLUSION: Base on our data we conclude that the newly developed thermal probe is accurate to determine neurosensory disturbances of the alveolar inferior nerve after sagittal split osteotomy. As compared with the more common testing methods, an advantage of our contemporary measurement device is the quantitative analysis of nerval function.
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Mandíbula/cirugía , Nervio Mandibular/fisiopatología , Osteotomía , Umbral del Dolor/fisiología , Complicaciones Posoperatorias/fisiopatología , Procesamiento de Señales Asistido por Computador/instrumentación , Termómetros , Sensación Térmica/fisiología , Adolescente , Adulto , Niño , Femenino , Estudios de Seguimiento , Humanos , Masculino , Mandíbula/inervación , Complicaciones Posoperatorias/diagnóstico , Estudios Prospectivos , Valores de Referencia , Umbral Sensorial/fisiologíaRESUMEN
Measuring devices for the quantitative assessment of thermal and pain thresholds are either simple and only suited for inexact tests or accurate and objective but expensive. The aim was there for to develop a cost effective device to enable a short and practical test of neurosensibility under clinical conditions. The result of this development is a new thermosensibility-measuring device (TSM) consisting of the measuring unit itself and a thermal probe. The data are registered and analysed through direct data transfer to a connected PC. Investigations carried out with this device revealed the construction to be efficient and easy to handle under clinical conditions. The TSM provides the examiner with the opportunity to monitor the neurosensory function of peripheral nerves in a reproducible way.
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Diagnóstico por Computador/instrumentación , Calor , Dimensión del Dolor/instrumentación , Umbral del Dolor/fisiología , Nervios Periféricos/fisiopatología , Examen Físico/instrumentación , Sensación Térmica , Diagnóstico por Computador/métodos , Diseño de Equipo , Análisis de Falla de Equipo , Humanos , Dimensión del Dolor/métodos , Examen Físico/métodos , Estimulación Física/instrumentación , Estimulación Física/métodos , Termografía/instrumentación , Termografía/métodos , Interfaz Usuario-ComputadorRESUMEN
A six-year-old girl is presented with an increasing mass involving the anterior vestibule and the floor of the mouth. Histologic and immunohistochemical examination revealed a poorly differentiated epitheloid leiomyosarcoma with destruction of the mandible. According to the CWS-96-study the patient underwent preoperative chemotherapy followed by complete resection of the mandibular body with the surrounding soft tissues. Recurrent tumor became evident only three months later on. The further treatment consisted of tumor resection, oral chemotherapy and irradiation. Nevertheless tumor control could not be achieved. The patient died of progressive disease 16 months after diagnosis. Leiomyosarcoma is extremely uncommon in childhood, especially with localisation in the oral cavity. Diagnosis is based on histologic examination and immunohistochemistry. In the presented case the lack of smooth muscle actin expression made diagnosis difficult. The preoperative chemotherapy could not achieve reduction of tumor size, so that extensive surgery became necessary. Estimation of the prognosis of the oral leiomyosarcomas in childhood is difficult. High grade tumours and involvement of bone seem to be associated with bad clinical outcome. The presented case is confirming that.
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Leiomiosarcoma , Neoplasias de la Boca , Adolescente , Adulto , Antineoplásicos/uso terapéutico , Biopsia , Niño , Preescolar , Terapia Combinada , Femenino , Humanos , Inmunohistoquímica , Lactante , Leiomiosarcoma/diagnóstico , Leiomiosarcoma/tratamiento farmacológico , Leiomiosarcoma/mortalidad , Leiomiosarcoma/patología , Leiomiosarcoma/cirugía , Suelo de la Boca/patología , Neoplasias de la Boca/diagnóstico , Neoplasias de la Boca/tratamiento farmacológico , Neoplasias de la Boca/mortalidad , Neoplasias de la Boca/patología , Neoplasias de la Boca/cirugía , Recurrencia Local de Neoplasia , Cuidados Preoperatorios , Pronóstico , Factores de Tiempo , Resultado del TratamientoRESUMEN
AIM: The temperature and pain thresholds of 30 patients with mandibular fractures were evaluated with a specially developed measuring device in a prospective study to examine neurosensory disturbances of the inferior alveolar nerve (IAN). PATIENTS AND METHODS: Measurements in 30 patients with 45 mandibular fractures were done before, immediately after, and over the course of half a year after operation. Outcomes of the thermosensitivity measurement (TSM) were compared to the results of the two point discrimination (2-PD) test, sharp/blunt test (SBT), and questioning the patients about their subjective feelings (SF). RESULTS: Post-traumatically, neurosensory testing revealed up to 2.8 degrees C (mean) increased thresholds as compared with the intact side. By contrast, post operative diagnostics clearly revealed up to 8.1 degrees C (mean) increased thresholds. Compared with the clinical sensory tests, the post-therapeutic (3-6 months postoperative) measurements with the TSM device proved a resensitization and threshold decrease by up to 3 degrees C. We found more exact and reproducible results of the TSM in comparison to those of the 2-PD and SBT for the evaluation of sensory disturbances of the IAN. Close agreements between the results of the TSM and the SF could be detected. CONCLUSION: Because of its sensitivity and accuracy in the quantitative detection of temperature and pain thresholds, the TSM is particularly suitable for evaluating neurosensory deficits and monitoring their progression.
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Fracturas Mandibulares/fisiopatología , Umbral del Dolor/fisiología , Trastornos de la Sensación/diagnóstico , Sensación Térmica/fisiología , Traumatismos del Nervio Trigémino , Adolescente , Adulto , Anciano , Umbral Diferencial/fisiología , Femenino , Estudios de Seguimiento , Humanos , Masculino , Mandíbula/inervación , Nervio Mandibular/fisiopatología , Persona de Mediana Edad , Examen Neurológico/instrumentación , Estudios Prospectivos , Reproducibilidad de los Resultados , Trastornos de la Sensación/fisiopatología , Procesamiento de Señales Asistido por ComputadorRESUMEN
Malignant tumors of the maxilla are rare. In addition to primary tumors metastatic disease has to be considered. Renal cell carcinomas, carcinomas of the breast, lung and adenocarcinomas are constituting the most frequent primary lesions for maxillary metastases. To the best of our knowledge, we present the first case of a mucinous sweat gland carcinoma metastasizing to the maxilla four years after primary diagnosis. Thirty-two months after resecting the hemimaxilla, there are no signs of local recurrence. Although skin tumors only rarely develop distant metastases, sweat gland carcinomas should be included in the differential diagnosis of tumors metastasizing to the maxilla.
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Adenocarcinoma Mucinoso/patología , Neoplasias Maxilares/secundario , Neoplasias de las Glándulas Sudoríparas/patología , Dedos del Pie , Anciano , Humanos , Masculino , Neoplasias Maxilares/patología , Neoplasias Maxilares/cirugía , Metástasis de la Neoplasia , Resultado del TratamientoRESUMEN
We describe here a new osteotome for submucous palatal osteotomy. It enables safe sectioning of the palatal suture in the submucosal plane for rapid, surgically-assisted maxillary expansion, using the approach from the piriform aperture.
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Osteotomía/instrumentación , Paladar Duro/cirugía , Suturas Craneales/cirugía , Diseño de Equipo , Humanos , Mucosa Bucal/cirugíaRESUMEN
The study was aimed at investigating the effect of an admixture of sodium hydrogen phosphate (NaP) on the pH value around degrading poly(D,L)lactide (PDLLA) and the possible improvement of PDLLA biocompatibility by coating its surface with heparin. PDLLA +/- NaP was injection-molded to form rods (20 x 3 x 2 (mm)) and cubes (3 x 2 x 2 (mm)). Half of the pure PDLLA samples were surface-coated using heparin. One rod and cube each of PDLLA, PDLLA + NaP and PDLLA/Hep were implanted into the dorsal muscles of 42 rats. From the 2nd to 52nd week after operation, pH measurements were performed in the environment around the implants. The samples were then harvested for histological and mechanical analyses. No significant decrease in pH-values was observed in the tissue around the implants. Pure PDLLA and PDLLA/Hep samples were macroscopically resorbed after 52 weeks, while the degradation of PDLLA + NaP was still in progress. Approximately 80% of the initial bending strength of PDLLA or PDLLA/Hep rods was present after six weeks, while the bending strength of PDLLA + Nap was reduced to 50% after 4 weeks. Heparin-coating of PDLLA did not improve its biocompatibility but did increase its resorption. While no significant effect of NaP on pH value was found, its admixture did reduce the mechanical characteristics of the implants.
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Materiales Biocompatibles Revestidos/química , Materiales Biocompatibles Revestidos/farmacología , Reacción a Cuerpo Extraño/patología , Heparina/química , Heparina/farmacología , Músculo Esquelético/patología , Fosfatos/química , Poliésteres/química , Animales , Materiales Biocompatibles Revestidos/síntesis química , Mezclas Complejas/síntesis química , Mezclas Complejas/química , Mezclas Complejas/farmacología , Masculino , Ensayo de Materiales , Músculo Esquelético/cirugía , Prótesis e Implantes , Ratas , Ratas WistarRESUMEN
PURPOSE: Up to now in maxillofacial surgery almost all inpatient treatments were reimbursed at the hospital's per diem rate. The real treatment cost is unknown and there is a lack of publications in this sphere. This study calculates the cost of surgical treatment of mandibular fractures. METHOD: The prospective study includes 104 patients whose mandibular fractures were treated using miniplate osteosynthesis. For each patient we took into account the time input by physicians and specialised nurses and calculated labour cost using the relevant wage rates. We added the cost for materials and drugs as well as for laboratory and radiographic examinations. Finally, we incorporated charges for the hotel and nursing components of inpatient treatment. RESULTS: The cost for the surgical treatment of mandibular fractures varied between 642 euro; for single and 1,070 euro; for triple fractures. The share of labour cost is about 1/3. Treatment cost varies with the length of hospital stay: 1,132 euro; for four days and 1,628 euro; for seven days on average. CONCLUSION: This prospective study can be compared with the recently published corresponding G-DRG rates. Moreover, the reported cost figures allow comparison with corresponding cost studies from other public health systems.
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Placas Óseas/economía , Fijación Interna de Fracturas/economía , Fracturas Mandibulares/economía , Programas Nacionales de Salud/economía , Adulto , Costos y Análisis de Costo , Grupos Diagnósticos Relacionados/economía , Femenino , Alemania , Precios de Hospital/estadística & datos numéricos , Humanos , Masculino , Fracturas Mandibulares/cirugía , Grupo de Atención al Paciente/economíaRESUMEN
AIMS: Comparison of the degradation of poly(D,L)lactide (Resorb X) or poly(lactide-co-glycolide) (LactoSorb) in vivo. MATERIAL AND METHODS: LactoSorb and Resorb X osteosynthesis plates were fixed at the lateral aspect of the femora of 26 Chinchilla rabbits using the respective osteosynthesis screws. After intraperitoneal injection of fluorochromes the screw plate bone blocks were resected after 1, 6, 12, 14, 16, 21, 26 months and radiologic, histologic as well as fluorescence microscopic examinations were carried out. RESULTS: Newly formed bone was detectable above and beneath the polymers 1 month after the implantation. The implants were totally covered by newly formed bone after 6 months. While the LactoSorb screws were found to be as birefringent as after 1 month, in the Resorb X screws a continuous resorption by phagocytizing marrow cells starting from the periphery was detectable. Resorb X was totally resorbed in histologic slides 12 months after implantation, while total resorption of LactoSorb lasted 14 months; both polymers were replaced by marrow cells. Bone remodeling was not finished 26 months after implantation in both polymers. CONCLUSION: Resorption of Resorb X was finished earlier than the resorption of LactoSorb. Both materials were found by fluorescence microscope to be completely resorbed after 12 or 14 months, but bone remodeling of the screw holes was not yet finished 26 months after implantation.
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Implantes Absorbibles , Placas Óseas , Fijación Interna de Fracturas/instrumentación , Ácido Láctico/farmacocinética , Ensayo de Materiales , Poliésteres/farmacocinética , Ácido Poliglicólico/farmacocinética , Polímeros/farmacocinética , Animales , Biodegradación Ambiental , Tornillos Óseos , Femenino , Fémur/patología , Fémur/cirugía , Microscopía Fluorescente , Oseointegración/fisiología , Copolímero de Ácido Poliláctico-Ácido Poliglicólico , ConejosRESUMEN
AIMS: The aim of this study was to evaluate the load resistance of mandibular angle fractures treated with a miniplate osteosynthesis according to Champy. MATERIAL AND METHODS: We evaluated 22 completely dentate patients with fractures of the angle in addition to 15 controls. An electric test procedure for the determination of the load resistance between the incisors, canines and molars was carried out 1-6 weeks after treatment. RESULTS: At 1 week postoperatively 90 N was registered between the molars while after 6 weeks this was 148 N. This revealed only 31% and 58% of the maximal vertical load found in the controls, respectively. CONCLUSION: The minipate osteosynthesis according to Champy offers a secure method in the treatment of mandibular angle fractures with sufficient stability. Maximum voluntary bite forces were not registered during the time of healing.
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Fuerza de la Mordida , Placas Óseas , Fijación Interna de Fracturas/instrumentación , Fracturas Mandibulares/cirugía , Soporte de Peso/fisiología , Adolescente , Adulto , Fenómenos Biomecánicos , Femenino , Humanos , Masculino , Fracturas Mandibulares/fisiopatología , Complicaciones Posoperatorias/fisiopatologíaRESUMEN
BACKGROUND: A method is introduced using a newly developed palatal distractor, which allows rapid transversal widening in cases of maxillary compression. METHODS: After osteotomy of the palate parallel to the sutura palatina mediana as well as to the lateral walls of the maxillary sinuses, the applied distractor permitted a transversal widening of 7.5 mm within 3 weeks. During the 3-month period of retention, multibanded orthodontic therapy could be performed. DISCUSSION: Because of the short treatment period, absence of recurrence, and easy handling for the patient this method is recommended for clinical use.
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Osteogénesis por Distracción/instrumentación , Técnica de Expansión Palatina/instrumentación , Placas Óseas , Tornillos Óseos , Diseño de Equipo , HumanosRESUMEN
OBJECTIVE: If the absorption kinetics of orally administered drugs in preoperative patients are influenced by high anxiety levels as maintained by Simpson and Stakes [1987], then this aspect would have to be taken into consideration in the preparation for surgery and would make dose adjustments necessary in such patients. METHODS: We differentiated and quantified the anxiety level in 40 patients, 4 - 5 hours prior to an operation, using the State-Trait Anxiety Inventory (STAI). Subsequently, all patients were given 1000 mg of paracetamol and serum levels were analyzed by means of HPLC. RESULTS: Over the first 3 hours after application there were no significant differences in the parameters C(max) and t(max) between patients with high levels of anxiety and patients with low levels of anxiety. However, AUC (area under curve) values were slightly higher in patients with high levels of anxiety. CONCLUSIONS: No clinically relevant differences in absorption parameters were observed in patients with high and low levels of anxiety.
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Acetaminofén/uso terapéutico , Ansiedad/tratamiento farmacológico , Acetaminofén/sangre , Acetaminofén/farmacocinética , Adolescente , Adulto , Anciano , Ansiedad/sangre , Área Bajo la Curva , Femenino , Humanos , Absorción Intestinal , Masculino , Persona de Mediana Edad , Cuidados PreoperatoriosRESUMEN
Maximal biting forces were evaluated in 22 patients with mandibular angle fractures treated with miniplate osteosynthesis according to Champy. An electric test procedure for evaluating the load resistance between the incisors, canines and molars was carried out 1 to 6 weeks following the treatment and additionally in 15 controls, too. This revealed that after surgical fracture treatment 1 week postoperatively only 31%, of the maximal vertical loading found in controls was registered. These values increased to 58% at the 6th week postoperatively.
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Fuerza de la Mordida , Análisis del Estrés Dental/métodos , Fijación de Fractura/instrumentación , Técnicas de Fijación de Maxilares/instrumentación , Fracturas Mandibulares/fisiopatología , Fracturas Mandibulares/cirugía , Adolescente , Adulto , Placas Óseas , Femenino , Curación de Fractura , Humanos , Masculino , Análisis por Apareamiento , Modelos Biológicos , Periodo Posoperatorio , Procesamiento de Señales Asistido por Computador , Estadísticas no Paramétricas , TransductoresRESUMEN
OBJECTIVE: Biodegradable osteosynthesis materials are not radio-opaque and therefore not visible on conventional X-rays. The aim of this study is to investigate the use of ultrasound for imaging biodegradable materials to detect and monitor the degradation process. METHODS: Forty-six patients had two different polylactide osteosynthesis fracture plate materials used for the fixation of midfacial fractures. A 7.5 MHz ultrasound transducer with a 4.2 x 0.9 cm footprint was used by two examiners at approximately 4-month intervals over 36 months to monitor changes of the latero-orbital and infra-orbital rims. RESULTS: Intrinsically amorphous 50 : 50 poly(D,L)lactide reached the maximum of thickness (about 300% of the initial thickness) between 14 and 18 months post-implantation and was totally resorbed in clinical and ultrasound examinations 30 months post-implantation. In 85 : 15 poly(L,D)lactide plates, the maximum of thickness (about 300% of the initial thickness) was reached between 22 and 26 months post-implantation and resorption was still in progress 36 months post-implantation. CONCLUSION: Ultrasound examinations are suitable for detecting and monitoring the degradation process of biodegradable osteosynthesis plates in the peri-orbital region.
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Implantes Absorbibles , Materiales Biocompatibles/química , Placas Óseas , Tornillos Óseos , Poliésteres/química , Ultrasonografía , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Estudios de Seguimiento , Fijación Interna de Fracturas/instrumentación , Curación de Fractura , Humanos , Masculino , Persona de Mediana Edad , Órbita/diagnóstico por imagen , Fracturas Orbitales/diagnóstico por imagen , Fracturas Orbitales/cirugía , Diseño de Prótesis , Propiedades de SuperficieRESUMEN
Aim of the study was to examine the influence of sodium hydrogenphosphate (NaP) on the pH value and the mechanical characteristics of degrading poly(D,L)lactide (PDLLA). Test rods of PDLLA with or without NaP amounting to 1, 10, 25 or 50 mol per 100 mol lactate, the degradation product of PDLLA, were produced by injection molding. Molecular weight and bending strength of the rods were measured before and after an accelerated in vitro-test (55 degrees C, Ringer's solution (RS)). For a long-time degradation test PDLLA-rods with or without 1 mol% NaP were placed in RS or Soerensen buffer solution (SB, pH 7.4) at 37 +/- 1 degrees C. Measurements of pH and determination of length, volume and weight of the samples were done in 2-4 week intervals up to the 52nd week after incubation. A pH-drop was measured in RS or SB containing pure PDLLA after 28 or 36 weeks respectively. Stabilization of the pH value due to admixed NaP delayed the degradation related pH drop for 8 weeks in RS or SB. A strong increase of length, volume and weight was measured in PDLLA + NaP-rods. In conclusion minimal stabilization of pH but also an increase of outer dimensions of the samples was found due to the admixture of NaP to PDLLA. Thus, an addition of substantially higher amounts than 1 mol% NaP in PDLLA can not be recommended, regardless of the positive effects on pH stabilization.
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Implantes Absorbibles , Fosfatos , Poliésteres , Polímeros , Humanos , Concentración de Iones de HidrógenoRESUMEN
The study was aimed at examining the in vivo degradation of pure poly(D,L)lactide (PDLLA) or PDLLA with an admixture of calciumphosphates. One rod (20 x 3 x 2 mm) and one cube (3 x 2 x 2 mm) of pure PDLLA, PDLLA with tricalciumphosphate (PDLLA + TCP) or PDLLA with calciumhydrogenphosphate (PDLLA + CHP), respectively, were implanted into the dorsal muscles of 50 male Wistar Albino rats. After definite intervals (from 2nd to 72nd week), pH measurements were performed in the environment of the implants. Afterwards, the cubes with their surrounding tissues were excised for histological examinations, measurements of the outer dimensions and mechanical analyses of the explanted rods were performed. No drop of more than 0.1 pH units was detectable in the tissue surrounding any type of implants. No advantageous effect of the calciumphosphates could be proved. A mild foreign body reaction could be observed around PDLLA implants. After 72 weeks, pure PDLLA had been totally resorbed from the extracellular space, the degradation of calciumphosphate-enriched PDLLA was still in progress. A large amount of inflammations occurred in the tissues surrounding PDLLA with an admixture of slowly degrading TCP or CHP, leading to two abscesses and four fistulas at PDLLA + TCP, and two abscesses and three fistulas at PDLLA + CHP implantation site. Bending strength of pure PDLLA was constant up to the 4th week post-implantation and reduced to 60% of the initial value up to the 12th week. No traces of crystallinity could be observed during the degradation of PDLLA. As a conclusion of the study, complete resorption from the extracellular space and tissue tolerance of pure PDLLA is proved. An admixture of small calciumphosphate particles is not suitable to improve the biocompatibility of PDLLA but leads to a decrease in the mechanical characteristics.
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Materiales Biocompatibles/metabolismo , Fosfatos de Calcio/metabolismo , Poliésteres/metabolismo , Animales , Materiales Biocompatibles/química , Biodegradación Ambiental , Fosfatos de Calcio/química , Elasticidad , Fijación Interna de Fracturas , Masculino , Ensayo de Materiales , Microscopía Electrónica de Rastreo , Peso Molecular , Poliésteres/química , Prótesis e Implantes , Ratas , Ratas Wistar , Estrés MecánicoRESUMEN
In a prospective study 1,106 impacted mandibular third molars were removed from 687 patients. Clinical, radiographic, and surgical factors were recorded. Postoperatively, we examined the modalities of common sensation in order to assess sensory deficit. The patients were followed up, until complete restitution occurred, or, if the sensibility failed to recover, for at least 6 months. A total of 3.6% of the operated sides demonstrated impairment of labial sensation, and 2.1% of lingual sensation. The vast majority of these disturbances subsided completely during the follow-up period. The incidence of persisting sensory diminution after 6 months was 0.91% for the inferior alveolar, and 0.37% for the lingual nerve. However, the degree of the persisting deficit was slight in most instances. The relationship between the recorded factors and the alteration of sensation was analysed by using the chi2 test. For the inferior alveolar nerve we found the patient's age, the development of the roots, the degree of impaction, and the radiographic position of the nerve canal to be significantly correlated to sensory deficit, as well as the surgical procedures in the depth of the socket and the intraoperative opening of the mandibular canal. As far as the lingual nerve is concerned, general anaesthesia and the individual operator were the main factors predictive of nerve damage.
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Traumatismos del Nervio Lingual , Tercer Molar/cirugía , Trastornos Somatosensoriales/etiología , Extracción Dental/efectos adversos , Diente Impactado/cirugía , Traumatismos del Nervio Trigémino , Adolescente , Adulto , Factores de Edad , Anciano , Anciano de 80 o más Años , Anestesia Dental , Distribución de Chi-Cuadrado , Niño , Competencia Clínica , Femenino , Humanos , Masculino , Mandíbula , Persona de Mediana Edad , Estudios Prospectivos , Radiografía , Factores de Riesgo , Raíz del Diente/anatomía & histología , Diente Impactado/diagnóstico por imagen , Diente Impactado/patologíaRESUMEN
AIM: A comparison of metal/osseous interface and bone remodelling after insertion of different types of titanium bone screws in vivo. MATERIAL: Samples of five of each of the following bone screw types were inserted into the anterior wall of the frontal sinus of five Göttingen minipigs: self-tapping micro- (1.5mm) and miniscrews (2.0 mm) or drill free micro- (1.5 mm) and miniscrews (2.0 mm) (Martin Medizintechnik, Tuttlingen, Germany). Screw length was 7mm. METHODS: Sequential intraperitoneal injections of fluorochromes were performed between the second and ninth postoperative week. After 6 months the pigs were sacrificed, the screw-bone-blocks resected, and microradiographic, histological and fluorescence microscopical examinations were carried out. RESULTS: Using drill free screws, mean screw/bone contact was 88.4% (miniscrews), or 93.8% (microscrews). With self-tapping miniscrews it was 54.9%, but in microscrews 81%; the differences were statistically significant (t-test: p<0.05). By fluorescence microscopy, the amount of bone remodelling (ratio of residual vs. newly formed bone) was measured. Significantly more of the residual bone was found in the region of the screw threads using drill free screws (miniscrews: mean 71.8%, microscrews: mean 67.9%) than in the region of screw threads with self-tapping screws (miniscrews: mean 33.1%, microscrews: mean 42.4%). CONCLUSION: The present data support the view that screw/bone contact with drill free screws was superior to that of self-tapping screws; the greater amount of original bone in the threads of drill free screws demonstrated that the insertion of drill free screws did not cause harm to the surrounding bone. Both results are important for osteosynthesis in regions where thin cortical bone is present, such as the central midface.
Asunto(s)
Remodelación Ósea/fisiología , Tornillos Óseos , Hueso Frontal/patología , Seno Frontal/patología , Titanio/química , Animales , Diseño de Equipo , Femenino , Colorantes Fluorescentes/administración & dosificación , Hueso Frontal/cirugía , Seno Frontal/cirugía , Osteón/ultraestructura , Procesamiento de Imagen Asistido por Computador , Inyecciones Intraperitoneales , Microrradiografía , Microscopía Fluorescente , Microcirugia/instrumentación , Oseointegración/fisiología , Estadística como Asunto , Propiedades de Superficie , Porcinos , Porcinos EnanosRESUMEN
Screw-bone contact (SBC) and bone remodeling of titanium drill-free screws or self-tapping screws should be compared. Each 10 titanium self-tapping miniscrews or microscrews, and each 10 titanium drill-free miniscrews or microscrews were inserted into the anterior wall of the frontal sinus of 5 Göttingen minipigs. Intraperitoneal injections of fluochromes (Xylenol, Calcein, Alizarincomplexon and Tetrazyklin) were performed between the 2nd and 9th postoperative week. The pigs were sacrificed after 6 months, the screw-bone blocks were resected and microradiographic, histologic and fluorescence microscopic examinations were carried out. In drill-free screws mean SBC was 88.4 (miniscrews) or 93.8% (microscrews). In self-tapping miniscrews mean SBC was 54.9, in microscrews 81%; the differences were significant in statistical analysis (t-test: p < 0.05). In fluorescence microscopy the amount of bone remodeling (ratio of residual versus newly formed bone) was measured. Significantly more of the residual bone was found in the region of the screw threads of drill-free screws (miniscrews: mean 71.8, microscrews: mean 67.9%) than in the region of screw threads of self-tapping screws (miniscrews: mean 33.1, microscrews: mean 42.4%; t-test: p < 0.05). The superior SBC of drill free screws in comparison to SBC of self-tapping screws and the higher amount of original bone in the threads of drill free screws explain the sufficient holding strength of drill free screws in clinical tests. Both results are important for osteosynthesis in regions where thin cortical bone is present, as in the central midface.