[Immunological response of patient with chronic salphingo-oophoritis to interference currents used in electrical sleep and balneotherapy]. / Izmenenie immunologicheskikh pokazatelei u bol'nykh khronicheskim sal'pingooforitom pod vliianiem interferentsionnykh tokov po metodu electrosna i bal'neoterapii.

The study included 105 women of a reproductive age with chronic nonspecific salpingooophoritis. The women were transcerebrally exposed to interference currents (IC). The immunological examination revealed that IC have an immunocorrecting effect on both cellular and humoral links of the immune system, correct imbalance of the immunoregulatory subpopulations confirmed by increased immunoregulatory index. Inclusion of balneotherapy potentiates analgetic, anti-inflammatory effects of transcerebral IC therapy, regulates balance of immunoregulatory T-cell subpopulations due to better differentiation of T-lymphocytes in the thymus.

[The use of cryomassage in the rehabilitative treatment of patients with duodenal peptic ulcer at the polyclinic stage]. / Primenenie kriomassazha v vosstanovitel'nom lechenii bol'nykh iazvennoi bolezn'iu dvenadtsatiperstnoi kishki na poliklinicheskom étape.

The proposed technique of cryomassage in outpatient setting promotes a complete healing of duodenal ulcer (DU) in patients with DU exacerbation. Healing of the ulcer is accompanied by improvement of blood flow in the zones of segmental innervation of the gastroduodenal system and by recovery of impaired cellular and humoral immunity in most of the patients.

[The interauricular laser therapy of rheumatoid arthritis]. / Interaurikuliarnaia lazernaia terapiia revmatoidnogo artrita.

Investigations have proved the ability of interauricular low-intensity infrared laser therapy (0.89 nm, 7.6 J/cm) to produce anti-inflammatory, immunomodulating action in patients with rheumatoid arthritis. The method has selective, pathogenetically directed immunomodulating effect the mechanism of which is similar to that of basic antirheumatic drugs and of intravenous laser radiation of blood. This laser therapy can be used as an alternative to intravenous blood radiation being superior as a noninvasive method. Interauricular laser therapy can potentiate the effects of nonsteroid anti-inflammatory drugs, cytostatics and diminish their side effects.

[The effect of carbon dioxide baths and applications of low-temperature peloids on the immune function of patients with psoriatic arthritis]. / Vliianie gazovykh uglekislykh vann i applikatsii peloidov nizkikh temperatur na immunnoe sostoianie bol'nykh psoriaticheskim artritom.

A trial of dry air effervescent baths and low-temperature peloid applications was made in 109 patients with psoriatic arthritis (PA). Marked response was achieved in patients who had received combined therapy with the above two modalities. The effect presented with lower articular index, weaker skin involvement, improvement of blood picture. These positive changes correlated with normalization of immune indices. The benefit persisted for 6-9 months.

[The combined treatment of patients with chronic nonspecific salpingo-oophoritis using a low-frequency magnetic field and iodobromine water]. / Kompleksnoe lechenie bol'nykh khronicheskimi nespetsificheskimi sal'pingooforitami nizkochastotnym magnitnym polem i iodobromnoi vodoi.

The studies of 116 females with chronic nonspecific salpingo-oophoritis demonstrate that combination of low-frequency magnetic field with iodine-bromine water effectively corrects immunological indices, i.e. improves T- and B-cell immunity, production of IgM and IgA, proportion of immunoregulatory subpopulations of T-lymphocytes.

[The effect of a low-frequency magnetic field on the clinico-immunological indices of patients with chronic inflammatory diseases of the organs of the female genital system]. / Vliianie nizkochastotnogo magnitnogo polia na kliniko-immunologicheskie pokazateli bol'nykh s khronicheskimi vospalitel'nymi zabolevaniiami organov zhenskoi polovoi sistemy.

Low-frequency magnetic field generated by the vaginal inductor used in 120 females with chronic genital inflammation promoted a decrease in leukocytosis, elevation of total population of T-lymphocytes, inhibition of high proliferative activity in PHA test. However, marked immunocorrection was not reached.

[The use of sodium chloride baths in patients with chronic bronchitis]. / Primenenie khloridnykh natrievykh vann u bol'nykh khronicheskim bronkhitom.

80 patients with chronic bronchitis took baths with sodium chloride concentration 20, 40, 60 g/l and temperature 37-38 degrees C. The baths produced a positive effect on central and regional hemodynamics, reduced inflammation and sensitization.

[The effect of the administration of different estrogens on the content of estrogen receptors in the cytosol and nuclear subfractions of liver cells and on the level of angiotensinogen in the blood plasma of rats]. / Vliianie vvedeniia razlichnykh éstrogenov na soderzhanie éstrogennykh retseptorov v tsitozol'noi i iadernoi subfraktsiiakh kletok pecheni i uroven' angiotenzinogena v plazme krovi krys.

The level of estrogen receptors (ER) in the cytosol and nuclear subfractions of female rat hepatocytes was studied 1 h and plasma angiotensinogen (AG) concentration 24 h after single and multiple administration of different doses of estradiol (E2) and synthetic estrogens. Synthetic weakly metabolized estrogens, used at doses corresponding to physiological concentrations of the natural female sex steroid, were shown to be much more effective than E2 in relation to ER redistribution between the cytosol and nuclear fractions of hepatocytes as well as in relation to the stimulation of AG production by the liver. Differences in the ER level in hepatocytic nuclei 1 h after single or multiple administration of the same estrogen were undetectable. An increase in a plasma AG level after a single injection of estrogens was noted after achieving a certain threshold (more than 3-fold as compared to the normal level) level of ER accumulation in hepatocytic nuclei. The sensitivity of AG production by the liver to a stimulating effect of low doses of estrogens was on the increase as a result of their repeated effect in prolonged administration and combined administration of E2 and glucocorticoids.

[The dynamics of the immunobiological effects in transcerebral microwave exposures]. / Dinamika immunobiologicheskikh éffektov pri transtserebral'nykh mikrovolnovykh vozdeistviiakh.

The trend in immunobiological responses to transcerebral action of decimeter microwaves was studied in intact rabbits. Transcerebral microwaves (120 mW/cm2) can alter functional activity of certain links of endocrine system due to possible activation of hypothalamus and hypophysis exposed to microwave electromagnetic field. Such exposure given in courses at early stages leads to an increase in the number of antibody-forming cells in the spleen, whereas total number of splenocytes is on the decrease.

[Effect of estradiol and other endocrine factors on the level and dynamics of estrogen receptors in the liver cells of rats]. / Vliianie éstradiola i drugikh éndokrinnykh faktorov na uroven' i dinamiku éstrogennykh retseptorov v kletkakh pecheni krys.

The authors studied the effects of different doses of estradiol (E2) on the level of estrogen receptors (ER) in female rat hepatocytes and the dynamics of ER distribution between the cytosol and nuclear cell fractions and compared the changes in the ER level in the liver in different endocrine states of the body. It was shown that the ER level in hepatocytes was far lower than in uterine cells and drastically increased during puberation and after ovariectomy. It was also found that the ER level in hepatocytes was dependent on pituitary functions. After a single injection of E2, the ER level in cytosol descended and that in the nucleus rose. The degree of ER reduction in cytosol and increase in the nucleus correlated with the dose of E2. The dynamics of intercombined changes in the levels of cytosol and nuclear ER was studied at different time intervals following the injection of different doses of the hormone. Some essential organ-specific features of E2 reception in the liver were revealed. Different mechanisms of the control of ER content in the liver and uterus are postulated.

[Comparative analysis of estrogen receptor level in the liver and angiotensinogen level in the blood plasma of rats after administration of estradiol in association with other endocrine factors]. / Sravnitel'nyi analiz dinamiki urovnia estrogennykh retseptorov v pecheni i angiotenzinogena v plazme krovi krys pod vliianiem vvedeniia éstradiola v sochetanii s vozdeistviem riada drugikh endokrinnykh faktorov.

A study was made of the level of hepatocyte estrogen receptors (ER) and of angiotensinogen [AG) in the blood plasma of rats after the administration of different doses of estradiol (E2) in combination with the exposure to some other endocrine factors. A single administration of E2 has been shown to cause two types of effects depending of the dose of a hormone administered and the time following injection: an increase in the AG level in the plasma and interrelated changes of the ER content in the cytosol and hepatocyte nuclei. These effects were most noticeable after the administration of 500 micrograms of E2. In this case the ER content decreased significantly in the cytosol and increased in the cell nucleus. An elevated ER level in the nucleus was preserved for 6-24 h and at this period AG production in the hepatocytes occurred and gradually increased within 24 h. An increase in AG production and the level and time of ER delay in the nuclei (r = +0.75, P less than 0.01) showed a high direct correlation. The expression of the effect of E2 high doses inducing AG synthesis depended on the body endocrine status which in its turn determined a certain level of E2 reception in hepatocytes. A low level of ER in the hepatocytes of hypophysectomized or immature rats corresponded to the absence or suppression of the E2 effect on AG production in the liver. An increase in the ER concentration in the cell as a result of the growth hormone administration to hypophysectomized or mature female rats was accompanied by the appearance or a rise of the sensitivity to the E2 effect.(ABSTRACT TRUNCATED AT 250 WORDS)