A prospective examination of the role of psychological (in)flexibility in posttraumatic stress: A cross-lagged panel design.

Functional contextualist models of psychopathology suggest that psychological inflexibility and psychological flexibility are of central importance for understanding the development and maintenance of posttraumatic stress (PTS) symptomatology. To our knowledge, these two constructs and their domain-specific factors (e.g., cognitive fusion, experiential avoidance) have not been assessed in their entirety and examined in relation to PTS symptoms using a longitudinal study design. As such, the primary aim of the present study was to use cross-lagged panel analysis, an analytic approach that allows stronger causal inferences to be made regarding the nature of temporal relations among study variables, to determine the directional relations among PTS symptoms and psychological flexibility and inflexibility over an eight-month time period. Trauma-exposed adults (N = 810), recruited online via Amazon's Mechanical Turk (MTurk), completed a battery of self-report measures via a secure online platform at three time points, spanning eight months. Results suggest that the relationship between psychological inflexibility and PTS symptoms is bidirectional and mutually reinforcing. In contrast, significant prospective relations were not observed between psychological flexibility and PTS symptoms. Results of a follow-up exploratory path analysis showed that cognitive fusion was the only psychological inflexibility subfactor that partially mediated the relationship between PTS symptoms from baseline to the eight-month follow-up assessment. Taken together, these results suggest that psychological inflexibility, and primarily the domain of cognitive fusion, maintains PTS symptoms following trauma exposure. As such, it may important to integrate cognitive defusion techniques into evidence-based treatments for Posttraumatic Stress Disorder (PTSD).

Investigating the specific domains of the cognitive attentional syndrome that predict posttraumatic stress symptoms: The moderating effect of attentional control.

The metacognitive model of posttraumatic stress disorder (PTSD) suggests that persistent use of the maladaptive self-regulation strategies that comprise the cognitive attentional syndrome (CAS) increases the likelihood of developing PTSD symptoms following trauma exposure. The metacognitive model also suggests that flexible regulation of attention might be protective against developing maladaptive outcomes that are associated with the CAS. The aims of this study were to (1) examine associations between all seven domains of the CAS and PTSD symptoms using a recently developed, multidimensional measure of the CAS, and (2) examine the moderating effect of self-reported attentional control on associations between the CAS and PTSD symptoms. Participants were trauma-exposed community adults (N = 237) who completed a battery of self-report measures. Results from linear regression analyses showed that worry, substance use, and internal threat monitoring accounted for unique variance in PTSD symptoms when all seven CAS domains were entered into the same model. Moderation analyses showed that attentional control dampened the effect of the CAS, specifically external threat monitoring, on PTSD symptoms. Study results support attentional control as a protective factor against the maladaptive effects of the CAS on PTSD symptoms.

Examining the Factor Structure and Incremental Utility of the Contrast Avoidance Questionnaires via Bifactor Analysis.

The negative emotional contrast avoidance model posits that pathological worry is maintained by the avoidance of negative emotional shifts. The Contrast Avoidance Questionnaires (CAQ-Worry and CAQ-General Emotion) aim to assess contrast avoidance beliefs and behaviors. Questions remain around the factor structures of the CAQs, whether such structures replicate in nonundergraduate samples, and whether their domain-specific factors are valid for independent use. This study used bifactor analysis in a large community sample (N = 827) to address these gaps in the literature. Results supported bifactor models of both measures. Complementary analyses supported the multidimensionality of the CAQ-Worry, including its strong general factor and independent use of two domain-specific factors, rather than the original three domain-specific factors. The CAQ-General Emotion's general factor was strong, but the merits of the Discomfort domain-specific factor require more exploration, and use of the Avoidance domain-specific factor is discouraged.

Executive functioning deficits exacerbate posttraumatic stress symptoms: A longitudinal mediation model.

Executive functioning (EF) consists of a set of related, but distinct, higher-level cognitive abilities that are used to organize and integrate lower-level processes in the service of engaging in goal-direct behavior. Evidence suggests that deficits in EF are a vulnerability factor for the development of posttraumatic stress (PTS) symptoms. Less understood, however, is the role that EF plays in symptom maintenance and exacerbation following trauma exposure. As such, the primary purpose of the present study was to determine whether EF deficits exacerbate PTS symptoms over the course of one year. A secondary aim of this study was to use a cross-lagged design to determine the directional relations among EF deficits and PTS. Trauma-exposed adults (N = 98) completed a clinical interview and self-report measures at an initial assessment session (Time 1 [T1]). Participants also completed self-report measures at 6- (Time 2 [T2]; n = 92) and 12-month (Time 3 [T3]; n = 91) follow-up sessions. As predicted, EF deficits at T2 mediated the relationship between PTS symptoms from T1 to T3, thus suggesting that EF deficits exacerbate PTS symptoms following trauma exposure. Results from a cross-lagged path analysis from T2 to T3 suggest that deficits in EF exert a stronger influence on the maintenance of PTS symptoms than vice versa. These results have implications for (a) identifying individuals that are at elevated risk for developing PTS symptoms, (b) developing precision medicine-based approaches for alleviating PTS symptoms, and (c) improving well-established PTSD treatments for those with relative deficits in EF.

Eye tracking evidence of threat-related attentional bias in anxiety- and fear-related disorders: A systematic review and meta-analysis.

CONTEXT: Cognitive theories of anxiety- and fear-related pathology suggest that individuals with these forms of pathology (versus those without) exhibit greater threat-related attentional bias (AB). However, there are a multitude of mixed and null findings in this area of research. Unlike other commonly used measures of AB, eye-tracking indices of AB exhibit acceptable reliability, and thus, may help clarify the relationship between AB and anxiety- and fear-related symptoms. OBJECTIVE: The purpose of this study was to conduct a meta-analysis, to determine whether there is evidence of a relationship between anxiety and fear-related symptoms and expressions of threat-related AB (i.e., reflexive orienting and maintenance) measured via free-viewing eye- tracking tasks. DATA SYNTHESIS: A total of 40 articles were retained for this meta-analysis. Significant relations were observed between anxiety and fear-related symptoms and both reflexive orienting toward threat (r = 0.13, 95% CI: 0.03, 0.22) and maintenance of attention on threat (r = 0.15, 95% CI: 0.05, 0.25). CONCLUSIONS: Results from the present study suggests that it may be important to develop attention bias modification interventions that target AB at both early (bottom-up) and later (top-down) stages of information processing to reduce anxiety- and fear-related pathology.

The Interactive Effect of Anxiety Sensitivity and Metacognitive Beliefs on Anxiety.

Anxiety sensitivity (AS) has been identified as a contributing factor to the development and maintenance of anxiety. Individuals with high AS are sensitive to bodily cues and anxiety-related thoughts and often misinterpret these stimuli as catastrophic or dangerous. Similarly, negative and positive metacognitive beliefs (i.e., beliefs about thinking) are believed to increase internal threat monitoring and the use of maladaptive coping strategies, which may increase the impact of AS on anxiety. As such, the purpose of the present study was to examine the moderating role of metacognitive beliefs on the relationship between anxiety sensitivity and anxiety. Adult participants (N = 417), recruited through an online crowdsourcing website, completed a battery of measures assessing the constructs of interest. Results from multiple linear regression indicated that the relationship between AS and anxiety became significantly stronger as negative and positive metacognitive beliefs increased, thus suggesting that negative and positive metacognitive beliefs may exacerbate the effect of AS on anxiety. The development of risk profiles that incorporate AS and negative and positive metacognitive beliefs may be beneficial for early identification of individuals at high risk for the development of anxiety.

Problematic Smartphone Use Influences the Relationship Between Experiential Avoidance and Anxiety.

Experiential avoidance (EA), an unwillingness to stay in contact with unwanted inner experiences (e.g., emotions, thoughts, and bodily sensations), has been implicated in the development and maintenance of anxiety. Individuals with high levels of EA are more likely to employ maladaptive coping strategies (i.e., avoidance behaviors), which exacerbates emotional distress and anxious arousal. As smartphone ownership has become increasingly common in recent years, problematic smartphone use (PSU) has been suggested to serve as a "safety behavior" in situations in which individuals believe that they might experience emotional discomfort. That is, individuals experiencing emotional distress and/or anxious arousal may overengage in the use of technology to relieve emotional distress. As such, the purpose of this study was to examine PSU as a moderator of the relationship between EA and anxiety. Adult participants (N = 294) recruited through Amazon's Mechanical Turk (MTurk), an online labor market, completed an online battery of self-reported measures. Results indicated that the relationship between EA and anxiety became significantly stronger as PSU increased, thereby suggesting that PSU may exacerbate the effect of EA on anxiety. These findings are a first step toward the development of risk profiles that incorporate EA and PSU. Such risk profiles may be beneficial for early identification and intervention for individuals at high risk for the development of anxiety.

The Moderating Effect of Attentional Control on the Relationship Between COVID Stress and Generalized Anxiety Symptoms.

The recent global pandemic (i.e., COVID-19) has had a serious impact on psychological health, as the stress associated with the pandemic increases the likelihood of developing clinically significant anxiety. Evidence suggests that attentional control may protect those individuals with outcome-specific vulnerabilities from developing maladaptive psychological outcomes. In the present study, attentional control was examined as a moderator of the relation between COVID-19 stress and generalized anxiety symptoms in a community sample (N = 359 adults). As predicted, the relationship between COVID-19 stress and anxiety was moderated by attentional control. Specifically, as attentional control decreased, the strength of the association between COVID-19 stress and anxiety increased. The results suggest that, among those with higher levels of COVID-19 stress, attentional control may act as a protective factor against developing anxiety. It may be beneficial as a matter of standard public health guidance to recommend that the general public engages in activities that are known to improve attentional control and alleviate emotional distress (e.g., mindfulness-based techniques) at the outset of a pandemic or other global catastrophe to reduce the likelihood that prolonged event-related stress will lead to impairing anxiety.

Are all pain tolerance tasks the same? Convergent validity of four behavioral pain tolerance tasks, self-reported capability for suicide, and lifetime self-injurious behaviors.

OBJECTIVES: Discrepancies persist regarding the extent to which different pain measures provide similar information and relate to capability for suicide and self-injurious behaviors. This study examined pain threshold, tolerance, and persistence across four modalities (cold, heat, pressure, shock) and assessed associations with self-reported capability for suicide, non-suicidal self-injury (NSSI), and suicide attempts. METHODS: A sample of 211 students who reported lifetime suicidal ideation completed four behavioral pain tasks and self-reported on capability for suicide, NSSI, and self-injurious behaviors. RESULTS: All pain thresholds, tolerances, and persistences were positively correlated across the four tasks. Pain facets were related to self-reported capability for suicide with small effect sizes but generally did not differ across suicide attempt or NSSI histories. CONCLUSIONS: Pain thresholds, tolerances, and persistences demonstrated convergent validity across the four modalities, suggesting that these tasks provide similar information. Although the relation between pain and self-injurious behaviors remains unclear, these tasks can generally be used interchangeably.

A longitudinal investigation of trauma-specific rumination and PTSD symptoms: The moderating role of interpersonal trauma experience.

BACKGROUND: Interpersonal trauma (IPT) is one of the most commonly reported types of traumatic experiences and has the greatest likelihood of resulting in a diagnosis of posttraumatic stress disorder (PTSD). Relative to other types of trauma, victims of IPT report greater trauma-specific rumination, whereby they focus on negative consequences of the trauma on their life. Theoretical and empirical work suggest trauma-specific rumination leads to elevated posttraumatic stress symptoms (PTSS); however, there has been a dearth of research examining how trauma type may impact this association. Therefore, the current longitudinal study examined how the experience of IPT moderates the relationship between trauma-specific rumination and later PTSS. METHOD: Participants (N = 204) enrolled in a clinical trial completed self-report measures of trauma experience, trauma-specific rumination, and PTSS at baseline and 1-month follow-up appointments. RESULTS: Results revealed that IPT moderated the relationship between baseline rumination and 1-month trauma symptoms, even after covarying for participant age and sex, treatment condition, negative affect, and number of previously experienced traumas. Further, this moderation effect was specific to the PTSD numbing cluster. LIMITATIONS: Major limitations include measurement of PTSS via PCL-C rather than the PCL-5, as well as a limited sample size, precluding moderation analyses of other trauma types. CONCLUSIONS: The current study provides novel findings demonstrating specificity of index trauma type in the longitudinal relationship between rumination and PTSS. Future work is needed to examine how IPT impacts the development of pathways between rumination and PTSS.

Examination of characteristics of ruminative thinking as unique predictors of suicide-related outcomes.

Rumination, a passive, repetitive perseveration on the causes, meaning, and consequences of one's distress, has been linked to suicidal ideation and behavior. Less is known, however, about which specific characteristics of rumination confer risk for suicide-related outcomes. This study examined associations between four features of rumination-frequency, duration, perceived controllability, and content-and current suicidal ideation, lifetime suicide plans, and lifetime suicide attempts. A sample of 548 adults (53.6% female, Mage = 36.54 years, 80.8% White/European American) recruited via Amazon's MTurk completed a battery of self-report measures online. The perceived controllability of rumination was uniquely associated with suicidal ideation, plans, and attempts, controlling for other characteristics of rumination, generalized worry, and demographic characteristics. Perceived controllability was also related to lifetime suicide plans and attempts above and beyond current suicidal ideation. Interpersonal and health-related content areas were also related to suicide-related outcomes, though these effects were inconsistent across outcome. Overall, perceived controllability over one's thoughts may be a key factor that confers risk along the suicidality continuum. Future research should replicate and extend these findings in diverse populations, using longitudinal designs, and with a variety of methodologies.

Examining characteristics of worry in relation to depression, anxiety, and suicidal ideation and attempts.

BACKGROUND: Pathological worry is defined as worry that is excessive, pervasive, and uncontrollable. Although pathological worry is related to depression, anxiety, and suicidal ideation, less is understood about what specific features of worry confer risk for these mental health conditions. The current study examined associations between four characteristics of worry-frequency, duration, controllability, and content-and self-reported symptoms of depression, anxiety, suicidal ideation, and lifetime suicide attempts. METHODS: A sample of 548 community participants (53.6% female, 45.4% male, 0.5% transgender male, 0.2% transgender female, and 0.2% gender non-binary), aged 19-98 years (M = 36.54, SD = 12.33), was recruited via Amazon's MTurk and completed a battery of self-report questionnaires online. RESULTS: Results indicated that controllability of worry was uniquely associated with depression, anxiety, and suicidal ideation above and beyond other characteristics of worry, demographic variables, negative affect, and future-oriented repetitive thinking. Lifetime suicide attempts were found non-significant to these mental health outcomes. Frequency of worry was also positively related to depression. LIMITATIONS: This study utilized a cross-sectional design with exclusive self-report measures. CONCLUSIONS: Overall, these findings suggest that controllability of one's thoughts may be a key transdiagnostic factor that confers risk for a variety of psychopathology-related concerns. Clinical relevance includes identifying potential risk factors for varying psychopathology. Future research should examine relationships between worry controllability and anxiety, depression, suicidal ideation, and attempts, within clinical samples and utilizing a variety of methodologies.

Evaluation of two web-based interventions in reducing the stigma of suicide.

Suicide is more highly stigmatized than most mental health conditions; however, no interventions have aimed to modify the stigma of suicide in the general population. This study tested the efficacy of two brief web-based interventions-psychoeducation and interpersonal exposure-in reducing suicide-related stigma in a student/community sample. A sample of 266 adults completed baseline measures of suicide-related stigma, were randomized into one of three conditions (psychoeducation, interpersonal exposure, control), in which they browsed an assigned website for twenty minutes, and completed post-intervention and one-month follow-up stigma measures. Results indicated that the two interventions were more efficacious than the control in reducing suicide-related stigma; this effect was accentuated for individuals without prior exposure to suicide. Although future research is needed to understand the mechanisms of change and the generalizability of these findings, it is possible that web-based interventions could be a cost- and time-effective avenue of targeting the widespread stigma of suicide.

Linking puberty and error-monitoring: Relationships between self-reported pubertal stages, pubertal hormones, and the error-related negativity in a large sample of children and adolescents.

The error-related negativity (ERN) is a negative deflection in the event-related potential occurring when individuals make mistakes. The ERN has been proposed as a biomarker for anxiety and a substantial amount of research suggests the ERN increases across development. Further, the ERN may relate to individual differences and the development of cognitive control. Despite the large quantity of research on this topic, there have been no studies focusing on the relationship between pubertal hormones and the ERN. Previous work suggests developmental increases may begin sooner for girls than for boys, suggesting that puberty may impact the ERN. The current study examined the relationship between pubertal hormones and the ERN amplitude in a sample of 99 females between 8 and 14 years old. Each participant and the parent who accompanied them completed the Pubertal Developmental Scale (PDS) to assess the degree to which pubertal indicators are present. Participants also completed a Go/NoGo Task while EEG was recorded and participants provided saliva samples for hormone assays. Results indicated that ERN was significantly related to both the dehydroepiandrosterone (DHEA) hormone and PDS scores. A simultaneous multivariate regression suggested that DHEA levels significantly predict the ERN, even when controlling for age, behavioral variables, and PDS. These findings suggest that ERN amplitude is related to DHEA levels, further linking puberty to developmental increases in the ERN. Future research should examine this relationship in the context of developmental increases in anxiety symptoms.

The Parent Sensitivity to Child Anxiety Index.

Anxiety sensitivity (AS) is the perception that anxiety symptoms and experiences have negative consequences, and has been identified as a risk factor for the development of anxiety disorders. AS has been measured in adults and in children, but to date, the construct of parent's sensitivity to their children's anxiety symptoms has not been identified, measured, or evaluated. The current study presents a novel measure of this construct, the Parent Sensitivity to Child Anxiety Index (PSCAI), and an initial evaluation of its psychometric properties. Factor analysis revealed a three-factor structure consisting of parents' concern for physical symptoms, concern of social evaluation, and fear of anxiety symptoms. The PSCAI demonstrated good internal consistency, and was positively correlated with relevant parental constructs such as parental accommodation, anxiety sensitivity, and trait anxiety. This new measurement system opens new avenues for researching the early development of anxiety disorders and the possibility for novel targeted interventions.