The role of leadership level in college students' facial emotion recognition: evidence from event-related potential analysis.

While the role of emotion in leadership practice is well-acknowledged, there is still a lack of clarity regarding the behavioral distinctions between individuals with varying levels of leadership and the underlying neurocognitive mechanisms at play. This study utilizes facial emotion recognition in conjunction with electroencephalograms to explore the temporal dynamics of facial emotion recognition processes among college students with high and low levels of leadership. The results showed no significant differences in the amplitude of P1 during the early stage of facial emotion recognition between the two groups. In the middle stage of facial emotion recognition, the main effect of group was significant on the N170 component, with higher N170 amplitude evoked in high-leadership students than low-leadership students. In the late stage of facial emotion recognition, low-leadership students evoked greater LPP amplitude in the temporal-parietal lobe when recognizing happy facial emotions compared to high-leadership students. In addition, time-frequency results revealed a difference in the alpha frequency band, with high-leadership students exhibiting lower alpha power than low-leadership students. The results suggest differences in the brain temporal courses of facial emotion recognition between students with different leadership levels, which are mainly manifested in the middle stage of structural encoding and the late stage of delicate emotional processing during facial emotion recognition.

Impact of Long-Term Shaolin Zen Meditation on Emotional Processing in Aging: A Visual ERP Study.

The aging process is always accompanied by a decline in cognitive and emotional functions. Although previous studies have identified the positive effects of different meditative practices on emotional and cognitive functions, few studies have investigated the most primitive Chinese meditation-Shaolin Zen meditation. In particular, data are extremely limited regarding the brain mechanism of the effects of Shaolin Zen meditation on cognitive and emotional functions during aging. The current study aimed to explore the effects of long-term Shaolin Zen meditation practice on event-related potentials (ERPs) during facial emotion recognition in aging. ERPs were recorded from 16 monks with long-term meditation experience and 20 controls without meditation experience. The significant age-related degenerative changes in the early ERP components did not present in the meditators but only in the controls without meditation experience. Additionally, we found no group differences in the late P3 component. These findings suggest that long-term Shaolin Zen meditation practice can counteract the age-related cognitive decline in the "down-top" automatic processing of emotional stimuli.

Working memory impairment in children orphaned by parental HIV/AIDS: An event-related potentials study.

A large body of literature has established that children orphaned by HIV/AIDS ('AIDS orphans') face numerous challenges, such as parental death, poverty, disrupted school attendance and stigma. All of these early life adversities can have long-lasting effects on brain function, especially the executive functions. Working memory, as one of the most studied aspects of executive functions, is also reported to be impaired in children with early adversity. However, limited data are available regarding how early life adverse events affect the neural dynamic associated with working memory processing in AIDS orphans. This study applied the electroencephalogram (EEG) technique to investigate the working memory process in 81 AIDS orphans and 62 non-orphan controls with n-back tasks. Results from EEG analysis and time-frequency analysis showed that AIDS orphans displayed smaller N2 and larger P2, P3 activation as well as enhanced theta and attenuated alpha band oscillations compared to the controls. The present findings indicated a deficit in working memory process in AIDS orphans and suggested that this deficit might be due to the impairments in attention allocation, detection and classification of stimuli and updating process in working memory.

The Impact of Gross Motor Skills on the Development of Emotion Understanding in Children Aged 3-6 Years: The Mediation Role of Executive Functions.

This study investigates the impact of gross motor skills on the development of emotion understanding and the role of executive function in the relation between gross motor skills and emotion understanding. A total of 662 children were tested for gross motor skills, emotion understanding, and executive function. Regression analysis showed that gross motor skills were significantly related to executive function. Multiple regression analyses showed that gross motor skills and executive function were significant predictors for emotion understanding. Furthermore, mediation analysis showed that executive function mediated the impact of gross motor skills on emotion understanding. Gross motor skills contributed to emotion understanding by improving children's executive function. The findings imply that a pathway from gross motor skills to emotion understanding is mediated by executive function, which offers a novel perspective on the developmental mechanisms of children's emotion understanding.

Inhibitory Control of Emotional Interference in Deaf Children: Evidence From Event-Related Potentials and Event-Related Spectral Perturbation Analysis.

Background: Impairment of interference control ability may reflect a more general deficit in executive functioning, and lead to an increase in internal-externalized problems such as impulsivity, which has been reported in deaf children. However, few researches have examined the neural mechanism of this impairment. Methods: This study applied the electroencephalogram (EEG) technique to investigate the interference control ability in 31 deaf children and 28 hearing controls with emotional face-word stroop task. Results: Results from behavioral task showed that deaf children exhibited lower accuracy compared to hearing controls. As for EEG analysis, reduced activation of ERP components in N1 and enhanced activation of ERP components in N450 have been found in deaf children. Besides, incongruent condition elicited larger N450 than congruent condition. Furthermore, for brain oscillation, alpha band (600-800 ms) revealed a reduced desynchronization in deaf children, while theta band (200-400 ms) revealed an enhanced synchronization in deaf children and incongruent condition, which were in line with ERP components. Conclusion: The present findings seem to indicate that the deficit during emotional interference control ability among deaf children might be due to the impaired attention allocation ability and emotional cognitive monitoring function during emotional conflict detection process. Consequently, reduced N1 and enhanced N450 might be due to early attention impairment causing more effort of deaf children later in emotional cognitive monitoring.

Metal-organic frameworks as a therapeutic strategy for lung diseases.

Lung diseases remain a global burden today. Lower respiratory tract infections alone cause more than 3 million deaths worldwide each year and are on the rise every year. In particular, with coronavirus disease raging worldwide since 2019, we urgently require a treatment for lung disease. Metal organic frameworks (MOFs) have a broad application prospect in the biomedical field due to their remarkable properties. The unique properties of MOFs allow them to be applied as delivery materials for different drugs; diversified structural design endows MOFs with diverse functions; and they can be designed as various MOF-drug synergistic systems. This review concentrates on the synthesis design and applications of MOF based drugs against lung diseases, and discusses the possibility of preparing MOF-based inhalable formulations. Finally, we discuss the chances and challenges of using MOFs for targeting lung diseases in clinical practice.

EEG Evidence of Altered Functional Connectivity and Microstate in Children Orphaned by HIV/AIDS.

Children orphaned by HIV/AIDS ("AIDS orphans") suffer numerous early-life adverse events which have a long-lasting effect on brain function. Although previous studies found altered electroencephalography (EEG) oscillation during resting state in children orphaned by HIV/AIDS, data are limited regarding the alterations in connectivity and microstate. The current study aimed to investigate the functional connectivity (FC) and microstate in children orphaned by HIV/AIDS with resting-state EEG data. Data were recorded from 63 children orphaned by HIV/AIDS and 65 non-orphan controls during a close-eyes resting state. The differences in phase-locking value (PLV) of global average FC and temporal dynamics of microstate were compared between groups. For functional connectivity, children orphaned by HIV/AIDS showed decreased connectivity in alpha, beta, theta, and delta band compared with non-orphan controls. For microstate, EEG results demonstrated that children orphaned by HIV/AIDS show increased duration and coverage of microstate C, decreased occurrence and coverage of microstate B, and decreased occurrence of microstate D than non-orphan controls. These findings suggest that the microstate and functional connectivity has altered in children orphaned by HIV/AIDS compared with non-orphan controls and provide additional evidence that early life stress (ELS) would alter the structure and function of the brain and increase the risk of psychiatric disorders.

The Role of Leadership Level in College Students' Decision-Making: Evidence From Event-Related Potential Analysis.

Although risk decision-making plays an important role in leadership practice, the distinction in behavior between humans with differing levels of leadership, as well as the underlying neurocognitive mechanisms involved, remain unclear. In this study, the Ultimatum Game (UG) was utilized in concert with electroencephalograms (EEG) to investigate the temporal course of cognitive and emotional processes involved in economic decision-making between high and low leadership level college students. Behavioral results from this study found that the acceptance rates in an economic transaction, when the partner was a computer under unfair/sub unfair condition, were significantly higher than in transactions with real human partners for the low leadership group, while there was no significant difference in acceptance rates for the high leadership group. Results from Event-Related Potentials (ERP) analysis further indicated that there was a larger P3 amplitude in the low leadership group than in the high leadership group. We concluded that the difference between high and low leadership groups was at least partly due to their different emotional management abilities.

Facial Expression Processing of Children Orphaned by Parental HIV/AIDS: A Cross-Sectional ERP Study with Rapid Serial Visual Presentation.

Existing behavioral studies have suggested that individuals with early life stress usually show abnormal emotional processing. However, limited event-related brain potentials (ERPs) evidence was available to explore the emotional processes in children orphaned by parental HIV/AIDS ("AIDS orphans"). The current study aims to investigate whether there are behavioral and neurological obstacles in the recognition of emotional faces in AIDS orphans and also to further explore the processing stage at which the difference in facial emotion recognition exists. A total of 81 AIDS orphans and 60 non-orphan children were recruited through the local communities and school systems in Henan, China. Participants completed a computer version of the rapid serial visual presentation (RSVP) task while recording ERPs. Behavioral results showed that orphans displayed higher response accuracy and shorter reaction time than the control (ps < 0.05). As for the ERPs analysis, the attenuated amplitude of N170 (i.e., an early component sensitive to facial configuration) was observed in AIDS orphans compared to the non-orphan control with happy and neutral faces; P300 (i.e., an endogenous component for affective valence evaluation in emotional processing) also showed significant differences in parietal lobe between groups, the non-orphan control group produced larger P300 amplitudes than orphans (p < 0.05). The results suggested that compared to the control group, AIDS orphans showed impaired facial emotion recognition ability with reduced brain activation.

Effect of Executive Function on Event-Based Prospective Memory for Different Forms of Learning Disabilities.

Students with learning disabilities (LDs) suffer from executive function deficits and impaired prospective memory (PM). Yet the specificity of deficits associated with different types of LDs is still unclear. The object of the present research was to compare subgroups of students with different forms of LDs (<25th percentile) on executive function and PM. Students with a mathematics disability (MD, n = 30), reading disability (RD, n = 27), both (RDMD, n = 27), or neither (typically developing, TD, n = 30) were evaluated on a set of executive functioning tasks (e.g., updating, inhibition, and shifting) and on PM. The results showed that students with MDs and RDMDs suffered from PM deficits. Among the subtypes of LDs, the deficit is different. The students with RDMDs showed a wide range of defects in PM, shifting, inhibition, and updating. In comparison, students with MDs experienced deficits in PM and shifting, while students with RDs experienced a deficit only in updating. For the RD group, the RDMD group and the TD group, updating, and shifting significantly predicted PM. For the MD group, only shifting significantly predicted PM performance, but PM deficits were not completely confined to shifting deficits.

The effect of time management training on time management and anxiety among nursing undergraduates.

Time management is an essential tool to enhance quality care and reduce stress in nursing professionals, who face a uniquely high-paced work environment with wide-ranging job demands. We evaluated the effect of a time-management training program on time management and anxiety in nursing undergraduate students. Study results showed that the training program significantly improved nursing undergraduates' time management and significantly decreased self-reported anxiety among the students post-intervention. This study is the first to examine the effect of a time-management training program based on time management disposition theory in China among Chinese nursing undergraduate students.

Effects of parental HIV on telomere length among children in rural China.

OBJECTIVE: Cumulative evidence has shown the adverse effects of HIV-related death and illness on children's psychosocial well-being. However, few studies have examined whether these factors can "get under the skin" to affect children's health. This study, therefore, examined the effects of HIV-related parental death on telomere length, a biomarker of cellular aging. This study further explored whether the results on telomere length were consistent with results based on self-report health outcomes, namely depressive symptoms. METHOD: A total of 117 children (10-17 years of age) affected by parental HIV (27 children living with HIV-positive parents and 90 AIDS orphans) from Henan China provided blood samples for telomere length assay and completed a survey for depressive symptoms and demographic information. RESULTS: Results showed that AIDS orphans had a shorter telomere length than children living with HIV-positive parents and that such differences in telomere length were more evident than were differences in depressive symptoms. There were no significant differences in telomere length or depressive symptoms between children who lost one parent and those who lost both. CONCLUSIONS: The results suggest that HIV-related parental death may contribute to accelerated telomere shortening and highlight that telomere length may be a novel and useful biomarker for health needs assessment in pediatric AIDS care. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

EEG oscillation evidences of altered resting-state brain activity in children orphaned by parental HIV/AIDS.

Early life adverse events in children orphaned by parental HIV/AIDS can have long-lasting effects on brain function. However, data are limited regarding the brain activation during resting state in these children. The current study aims to investigate the brain oscillation at rest in children orphaned by HIV/AIDS using resting-state EEG data. Data were derived from a larger neurodevelopmental study in which 90 children aged 9-17 years orphaned by AIDS and 66 matched controls were recruited through the local communities and school system. Children (63 orphans and 65 controls) who had resting-state EEG data and completed the Teacher-Child Rating Scale (T-CRS) were included in the current analysis. EEG results showed that children orphaned by HIV/AIDS had increased theta activity in the midline region, decreased beta activity in left hemisphere and overall increased theta/beta power ratio. Furthermore, the theta/beta ratio is positively correlated with learning problem and acting out scores, and negatively correlated with task orientation and peer social skill activities. Findings support that children orphaned by HIV/AIDS demonstrate different brain activity compared to non-orphan controls and also suggest that the EEG activities in resting state may serve as useful indicators of children's behavioral problems.

How Social Power Affects the Processing of Angry Expressions: Evidence From Behavioral and Electrophysiological Data.

With the help of event-related potentials (ERPs), the present study used an oddball paradigm to investigate how both individual and target power modulate neural responses to angry expressions. Specifically, participants were assigned into a high-power or low-power condition. Then, they were asked to detect a deviant angry expression from a high-power or low-power target among a series of neutral expressions, while behavioral responses and electroencephalogram (EEG) were recorded. The behavioral results showed that high-power individuals responded faster to detect angry expressions than low-power individuals. The ERP analysis showed that high-power individuals showed larger P3 amplitudes in response to angry expressions than low-power individuals did. Target power increased the amplitudes of the P1, VPP, N3, and P3 in response to angry expressions did, but decreased the amplitudes of the N1 and N170 in response to angry expressions. The present study extended previous studies by showing that having more power could enhance individuals' neural responses to angry expressions in the late-stage processes, and individuals could show stronger neural responses to angry expressions from high-power persons in both the early- and late-stage processes.

Inhibitory control of emotional interference in children with learning disorders: Evidence from event-related potentials and event-related spectral perturbation analysis.

An impairment in interference inhibitory control ability has been reported in children with learning disorders (LD), but few studies have examined the neural mechanism of this impairment. This study applied electroencephalogram (EEG) technique to investigate the emotional interference inhibitory control ability in 25 LD children and 22 non-LD controls with face-word emotional Stroop task. Results from behavioral tasks showed that LD children exhibited lower accuracy and longer reaction times. The EEG analysis showed that the non-LD children displayed significant interference effects both in the ERP components, with N2, N450 and SP exhibiting a larger activation in incongruent condition than the congruent condition, and brain oscillation, with early and late alpha demonstrating a larger desynchronization in the incongruent condition compared to the congruent condition. However, all these interference effects were absent in the LD children except the SP component. The present findings seem to indicate that the deficit during emotional interference control ability among children with LD might be due to the impaired attention allocation ability during emotional conflict detection process. Future research is needed to replicate these results and to explore the biochemical mechanisms between the impaired emotional interference inhibitory control ability and impaired attentional control ability.

Facial emotion recognition in deaf children: Evidence from event-related potentials and event-related spectral perturbation analysis.

Impairment of facial emotion recognition ability has been reported in deaf children, but few researches have examined the neural mechanism of this impairment. This study applied the electroencephalogram (EEG) technique to investigate the emotion recognition ability in 31 deaf children and 30 hearing controls with facial emotion recognition task. Results from behavioral task showed that deaf children exhibited lower accuracy compared to hearing controls. As for EEG analysis, results showed that deaf children showed diminished activation in the early (N1、P1), middle (N170) and late stages (late positive potential, LPP) compared to hearing controls. In addition, for brain oscillation, alpha band (400-800 ms) also revealed a reduced desynchronization in deaf children. The present findings seem to indicate that the deficit during facial emotion recognition ability among deaf children might be due to the impairments in visual processing, attention and emotional semantic distribution ability during facial emotion recognition processing.

The ANK3 gene and facial affect processing: An ERP study.

ANK3 is one of the most promising candidate genes for bipolar disorder (BD). A polymorphism (rs10994336) within the ANK3 gene has been associated with BD in at least three genome-wide association studies of BD [McGuffin et al., 2003; Kieseppä, 2004; Edvardsen et al., 2008]. Because facial affect processing is disrupted in patients with BD, the current study aimed to explore whether the BD risk alleles are associated with the N170, an early event-related potential (ERP) component related to facial affect processing. We collected data from two independent samples of healthy individuals (Ns = 83 and 82, respectively) to test the association between rs10994336 and an early event-related potential (ERP) component (N170) that is sensitive to facial affect processing. Repeated-measures analysis of covariance in both samples consistently revealed significant main effects of rs10994336 genotype (Sample I: F (1, 72) = 7.24, P = 0.009; Sample II: F (1, 69) = 11.81, P = 0.001), but no significant interaction of genotype × electrodes (Ps > 0.05) or genotype × emotional conditions (Ps > 0.05). These results suggested that rs10994336 was linked to early ERP component reflecting facial structural encoding during facial affect processing. These results shed new light on the brain mechanism of this risk SNP and associated disorders such as BD. © 2016 Wiley Periodicals, Inc.

Effect of rs1344706 in the ZNF804A gene on the connectivity between the hippocampal formation and posterior cingulate cortex.

ZNF804A is one of the most promising candidate genes for schizophrenia. Previous fMRI studies have repeatedly shown an association between SNP rs1344706 in this gene and the functional connectivity from the right dorsolateral prefrontal cortex (rDLPFC) to the left hippocampal formation (lHF) during the N-back task. However, the rDLPFC-lHF functional connectivity included several subconnections and it is not known whether rs1344706 plays the same role in these subconnections. This study addressed that question using both fMRI and DTI data of 87 subjects. First, we replicated the association between rs1344706 and the rDLPFC-lHF functional connectivity using our fMRI data from the N-back task. Second, we reconstructed fiber connections between rDLPFC and lHF using our DTI data, which included three subconnections: from lHF to posterior cingulate cortex (PCC), from PCC to anterior cingulated cortex (ACC), and from ACC to rDLPFC. We found that only the lHF-PCC tract showed significantly lower fractional anisotropy (FA) in risk allele homozygotes. Finally, we analyzed the fMRI data (from the N-back task and the resting state). Both consistently showed relatively lower lHF-PCC functional connectivity in risk allele homozygotes. Taken together, the disconnectivity of the lHF-PCC tract seems to be a plausible intermediate phenotype that links rs1344706 and schizophrenia.