RESUMEN
This work deals with the systematics and taxonomy of orthobunyaviruses, little-studied dangerous and new iruses Akabane, Aino, Schmallenberg, Cache Valley diseases, Oropouche fever. The significance of the reassortment mechanism of their origin and diversification is discussed.
Asunto(s)
Infecciones por Bunyaviridae/epidemiología , Orthobunyavirus/genética , Virus Reordenados/genética , Zoonosis/epidemiología , África/epidemiología , Animales , Infecciones por Bunyaviridae/patología , Infecciones por Bunyaviridae/virología , Europa (Continente)/epidemiología , Humanos , América Latina/epidemiología , Orthobunyavirus/clasificación , Orthobunyavirus/patogenicidad , Filogenia , Virus Reordenados/clasificación , Virus Reordenados/patogenicidad , Zoonosis/patología , Zoonosis/virologíaRESUMEN
The results of experimental infection of seronegative calves with three non-cytopathogenic (NCP) isolates of BVDV isolated from cattle with different clinical manifestations of the disease belonging to genotype 1 (subgenotype 1a, 1b and 1d) are presented. All tested isolates showed the virulence for seronegative calves 4 to 6 months of age. Belonging to biotype did not correlate with the ability of the virus to infect the lymphoid tissues and to induce leukopenia. All isolates of the virus led to "transiting" leukopenia (up to 2880-3800 kl/mm3) for 8-10 days after infection. Isolate cluster 1d was more virulent and caused the development of a mild respiratory syndrome and short-term diarrhea. The virulence was "strain-dependent".
Asunto(s)
Diarrea Mucosa Bovina Viral/virología , Virus de la Diarrea Viral Bovina/patogenicidad , Virulencia/genética , Animales , Diarrea Mucosa Bovina Viral/patología , Bovinos , Virus de la Diarrea Viral Bovina/genéticaRESUMEN
Bovine viral diarrhea (BVD) is one of the greatest challenges for breeding and commercial livestock. It is characterized by lesions of the respiratory and gastrointestinal tract, abortion, infertility, immune deficiency, and persistence of the pathogen. In this work, a set of measures for the rehabilitation and prevention of BVD in cattle is described. It includes the data of the literature, guidance documents for the diagnosis and control of BVD adopted by OIE, EU countries, USA, as well as the results of this research.
