Asunto(s)
Endoscopía Gastrointestinal , Hematemesis/diagnóstico , Hematemesis/epidemiología , Factores de Edad , Femenino , Hematemesis/terapia , Pruebas Hematológicas , Humanos , Recién Nacido , Masculino , Prevalencia , Pronóstico , Medición de Riesgo , Índice de Severidad de la Enfermedad , Tasa de SupervivenciaRESUMEN
The extent of tumor involvement, necrosis, reticulin, and megakaryocytosis were assessed in 25 patients with small cell lung cancer in their bone marrow at diagnosis. The pattern of marrow involvement was compared with clinical outcome and tolerance of therapy. Any marrow involvement, no matter how minor, is a poor prognostic factor. Neither more extensive involvement, nor greater marrow fibrosis significantly worsened the prognosis.
Asunto(s)
Médula Ósea/patología , Carcinoma de Células Pequeñas/patología , Neoplasias Pulmonares/patología , Carcinoma de Células Pequeñas/mortalidad , Humanos , Neoplasias Pulmonares/mortalidad , PronósticoAsunto(s)
Metotrexato/efectos adversos , Síndrome de Dificultad Respiratoria/inducido químicamente , Humanos , Inyecciones Espinales , Linfoma/tratamiento farmacológico , Masculino , Metotrexato/administración & dosificación , Persona de Mediana Edad , Neoplasias Nasofaríngeas/tratamiento farmacológicoRESUMEN
This report describes a patient who presented with a diffuse malignant central nervous system (CNS) process composed of cells with monocytic differentiation one year before the development of acute monocytic leukemia. A similar presentation has been documented for acute lymphocytic leukemia, but to the best of our knowledge, this is the first report to detail a diffuse CNS malignancy as the presenting symptom for acute monocytic leukemia.
