The effects of Yakson touch and gentle human touch on preterm infants: A systematic review and meta-analysis.

We aim to collect the evidence of efficacy of Gentle Guman Touch (GHT) and Yakson Touch in preterm neonates as pain relief, heart rate, oxygen saturation, and urine cortisol level. We made our search through PubMed, Web of Science, Scopus, and Cochrane by the mid of March 2023. Randomized control trials (RCTs) were included, and the Cochrane risk of bias tool was utilized to assess their quality. Using Review Manager software, a meta-analysis was conducted. We computed the mean difference (MD) with a 95% confidence interval (CI) for the continuous data. During the examination, the Neonatal Infant Pain Scale (NIPS) was significantly reduced in the touch group compared to the control group (MD = -3.40, 95% CI [-4.15 to -2.64], P-value= 0.00001). After the examination, the NIPS score was also reduced by both Yakson touch and GHT compared to the control (MD = -2.14, 95% CI [-3.42 to -0.85], P-value <0.00001). Yakson touch and GHT are non-pharmacological, easy, and safe methods that can be used for painful interventions to reduce the pain experience of preterm infants from variable interventions. Both methods improved infant sleep and behavior. Preterm infants' heart rates and oxygen saturation were unaffected by Yakson touch or GHT.

Double-balloon catheter vs dinoprostone (PGE-2) insert for labour induction: A meta-analysis of 2493 pregnancies.

Induction of labor (IOL) is the stimulation of the uterus during pregnancy to begin the onset of labour. Nearly two of five pregnancies require IOL. We compared the effectiveness of double-balloon catheter (DBC) with dinoprostone (PGE-2) insert for labour induction from previous studies. We included randomized controlled trials (RCTs) that compared the safety and efficacy of DBC to PGE-2. To evaluate the studies, we utilized the Cochrane tool for risk of bias assessment. The rates of vaginal birth and cesarean section were the primary outcomes. We included ten RCTs in this meta-analysis with a total sample of 2493 singleton pregnancies. After 24 hours, there was no significant difference in the delivery rates between DBC and PGE-2 s [R.R=1.08, 95% CI, (0.77, 1.52), P.value=0.65], and the rate of cesarean delivery [R.R=1.03, 95% CI, (0.90; 1.18), P.value=0.65]. The DBC showed a significantly higher oxytocin use rate compared to the PGE-2 group [R.R=1.77, 95% CI, (1.41; 2.32), P.value<0.0001]. In the PGE-2 group, there was a significantly higher risk of uterine hyperstimulation, tachysystole, and umbilical artery PH levels below 7. There was no significant difference in the efficacy between the PGE-2 and DBC in terms of delivery rate in 24 hours and the rate of cesarean delivery except for a slight BISHOP score improvement with DBC. However, DBC showed a higher rate of oxytocin use compared to the PGE-2, the DBC seems to be safer with a lower risk of umbilical artery PH < 7, uterine hyperstimulation, and tachysystole incidence than PGE-2.

Spontaneous cholesteatoma of the external auditory canal: the utility of CT.

Spontaneous external auditory canal (EAC) cholesteatoma is a rare disease. The symptoms are nonspecific. It is diagnosed by clinical examination and radiological investigation. The clinical examination alone is often insufficient for accurately assessing spread of the cholesteatoma into the temporal bone, meaning cross-sectional imaging modalities are required, and specifically computed tomography. We report three cases of spontaneous cholesteatoma of the external auditory canal. All of our patients underwent surgery. In two cases, the cholesteatoma was restricted to the external auditory canal, while in one case, it was complicated by a fistula with the lateral semicircular canal. Good anatomical and functional results were obtained in all three cases, with the external auditory canal patent and a good calibre on completion.

[Neonatal renal vein thrombosis in a heterozygous carrier of both factor V Leiden and the MTHFR gene mutation]. / Thrombose néonatale de la veine rénale et double hétérozygotie pour la mutation du facteur V de Leiden et du gène de la MTHFR.

Renal vein thrombosis (RVT) is a rare but potentially serious neonatal disease. Its epidemiology and its clinical and biological expression are currently well known, but its etiological exploration, like that of venous thromboembolism, is increasingly complex. Perinatal risk factors such as prematurity, dehydration, and birth asphyxia have lost their direct accountability at the expense of their interaction with constitutional disorders of hemostasis. We report a case of RVT in a newborn who was a heterozygous carrier of both factor V Leiden and the methylene tetrahydrofolate reductase (MTHFR) gene mutation. We recall the clinical and epidemiological characteristics. A search for inborn blood coagulation disorders should be systematic in the newborn infant with venous thrombosis because of the risk of recurrence, taking into account perinatal factors and maternal thrombophilia (especially if RVT is established during the prenatal period).

[Congenital cholesteatoma in children]. / Cholestéatome congéntial.

OBJECTIVES: To report on two cases of congenital cholesteatoma in patients aged 1 month. To review the clinical and radiological features of congenital cholesteatoma and to clarify the contribution of the CT scan in the diagnosis and the preoperative workup. PATIENTS AND METHODS: The authors report two observations of congenital cholesteatoma. These children were investigated using high-resolution CT. The treatment was surgical in both cases. RESULTS: The children were 1 month old, presenting with facial paralysis. In the otoscopic exam, the tympanic membrane was normal in both cases, with a whitish retrotympanic soft mass. The diagnosis of congenital cholesteatoma was made based on the CT data. CONCLUSION: Congenital cholesteatoma is rare. Otoscopic examination must be undertaken during the physical exam of a child at a young age to establish an early diagnosis. CT scan allows positive diagnosis and a precise preoperative workup.

Primary hydatid disease of the thigh. A rare location.

Primary muscle hydatidosis is very rare, accounting for less than 1% of hydatid cyst locations. Clinical symptoms are insidious and non-specific causing a frequent delay in diagnosis. Intramuscular hydatid disease can cause a variety of diagnostic problems, especially in the absence of typical radiologic findings. We report the observation of an 82-year-old man consulting for inguinal tumefaction with radiological exploration suggestive of hydatid cyst of the adductors muscles. Magnetic resonance imaging (MRI) is helpful in diagnosis, since it reveals a very suggestive aspect and demonstrates the relationship between cysts and adjacent structures. Treatment of muscle echinococcosis is based on surgery, which is curative and incurs a low risk of local relapse.

A rare cause of non discal sciatica: schwannoma of the sciatic nerve.

Schwannomas are peripheral nerve sheath tumors. Schwannomas arising in the sciatic nerve are considered a rare condition. Their symptomatology usually mimics sciatic pain due to a herniated disc, which can delay the diagnosis. We report the case of a patient with chronic sciatica in whom Magnetic Resonance Imaging (MRI) examination of the right thigh revealed a tumor of the sciatic nerve. Excision of the tumor was easily performed without neural lesioning. Histopathological examination revealed the tumor to be a schwannoma. No neurologic deficit was noted postoperatively which confirms the good prognosis of this tumor.

[Megalencephalic leukoencephalopathy with subcortical cysts: report of 4 new cases]. / La leucoencéphalopathie mégalencéphalique avec kystes sous-corticaux: description de 4 nouveaux cas.

Megalencephalic leukoencephalopathy with subcortical cysts or Van der Knapp disease is a rare entity that has recently been identified. It is characterized by the presence of macrocephaly, epilepsy and a slowly progressive spastic cerebellar syndrome. The culprit MLC1 gene is located on chromosome 22. MRI provides valuable data for diagnosis characterized by diffuse white matter lesions with subcortical cysts. We report four cases of megalencephalic leukoencephalopathy with subcortical cysts from two different families.

[Osteoid osteoma of the talus and simple bone cyst of the homolateral calcaneus. A rare association]. / Ostéome ostéoïde du talus et kyste osseux essentiel du calcanéus homolatéral. Une association rare.

Osteoid osteoma and simple bone cyst are readily observed in long bones, but are much less common in the short bones of the foot. The association of these two tumors in the same foot is exceptional. We report the case of a 15-year-old girl who presented an osteoid osteoma of the talus and a simple bone cyst of the calcaneus of the left foot. The patient complained of pain in the rear foot for four months which worsened at night and was of the inflammatory type. The physical examination was normal. Standard x-rays revealed a simple bone cyst in the calcaneus which could not explain the nighttime inflammatory pain. Scintigraphy and computed tomography of the left foot revealed an osteoid oseoma of the talus. Biopsy total resection of the osteoid osteoma with curettage and filling with cancellous bone of the simple bone cyst were performed. The patient has been free of recurrence at three years follow-up.

[Cherubism: a new case with review of literature]. / Le chérubisme: à propos d'une nouvelle observation avec revue de la littérature.

OBJECTIVES: To evaluate radiological characteristics of cherubism. MATERIAL AND METHODS: We report the case of a 7-year-old boy presented with facial deformity, bilateral mandibular swellings, right exophthalmia and dislocated teeth. Panoramic radiograph, Computed tomography scan and MR imaging were performed. RESULTS: Panoramic radiograph revealed multiloculated osteolysis involving the entire mandible and the right maxilla with dislocated teeth. Computed tomography scan showed multicystic expansive bony masses without cortical disruption occupying the mandible and right maxilla with extension to the orbital floor. On MR, these lesions demonstrated intermediate inhomogeneous signal intensity on T1 and T2 weighted images with high enhancement after gadolinium administration. MRI was useful in identifying orbital involvement. These clinical and radiological findings are in favor of the diagnosis of cherubism. CONCLUSION: Cherubism is a rare hereditary benign lesion of the mandible that appears in childhood as bilateral painless swellings which progress until puberty, then spontaneously regress. Plain radiographs and computed tomography scan are sufficient for diagnosis. MR imaging is useful to study the expansion to soft tissues, in particular in the aggressive forms, and establish preoperative vascular assessment. The treatment is plastic and aims to correct the facial deformities.