1.
Chem Commun (Camb)
; 59(90): 13510-13513, 2023 Nov 09.
Artículo
en Inglés
| MEDLINE
| ID: mdl-37885305
RESUMEN
Sequential peptide coupling plays a central role in chemical protein synthesis. This paper describes a new peptide derivative, peptide-aminothiazoline (At), whereof the C-terminus is functionalized with 2-aminothiazoline. Peptide-At streamlined the sequential peptide ligation in a one-pot manner and demonstrated the convergent synthesis of a circular protein and homogeneous glycoproteins.