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1.
Nanotechnology ; 23(25): 255101, 2012 Jun 29.
Artículo en Inglés | MEDLINE | ID: mdl-22652407

RESUMEN

Recent experiments have shown unambiguously that living cells respond to the nano-topography of surfaces they grow on-specifically, the fate of stem cells grown on nano-porous titania or alumina have been shown to be decided by the pore size. However, most experiments have focused on pore size or pitch. Here we show that in addition to pore size and pitch, the depth of the pores has a profound effect on cell morphology and the arrangement of the actin cytoskeleton.


Asunto(s)
Óxido de Aluminio/química , Técnicas de Cultivo de Célula/instrumentación , Fenómenos Fisiológicos Celulares/fisiología , Nanoporos/ultraestructura , Nanotecnología/instrumentación , Citoesqueleto de Actina/química , Línea Celular , Humanos , Microscopía Fluorescente , Porosidad , Propiedades de Superficie
2.
Anal Bioanal Chem ; 374(4): 688-94, 2002 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-12397494

RESUMEN

An overview is given on the use of scanning tunneling microscopy (STM) for investigation of the adsorption of hydrogen on Si(111)7 x 7 both at room temperature and at elevated temperature to finally obtain a hydrogen-saturated surface of Si(111). The initial stages are characterized by high reactivity of Si adatoms of the 7 x 7 structure. After adsorption of hydrogen on the more reactive sites in the beginning of the adsorption experiments a regular pattern, which is different for room and elevated temperature, is observed for the less reactive sites. In agreement with previous work, local 1 x 1 periodicity of the rest atom layer and the presence of di- and trihydride clusters is observed for hydrogen-saturated surface. STM has also been used to characterize surfaces from which the hydrogen atoms have been removed by thermal desorption. Finally, tip-induced desorption by large positive sample-bias voltages and by increasing the tunneling current will be described.

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