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Expert Rev Vaccines ; 16(4): 313-328, 2017 04.
Artículo en Inglés | MEDLINE | ID: mdl-27820969

RESUMEN

INTRODUCTION: The 2015 Global Meningococcal Initiative (GMI) meeting discussed the global importance of meningococcal disease (MD) and its continually changing epidemiology. Areas covered: Although recent vaccination programs have been successful in reducing incidence in many countries (e.g. Neisseria meningitidis serogroup [Men]C in Brazil, MenA in the African meningitis belt), new clones have emerged, causing outbreaks (e.g. MenW in South America, MenC in Nigeria and Niger). The importance of herd protection was highlighted, emphasizing the need for high vaccination uptake among those with the highest carriage rates, as was the need for boosters to maintain individual and herd protection following decline of immune response after primary immunization. Expert commentary: The GMI Global Recommendations for Meningococcal Disease were updated to include a recommendation to enable access to whole-genome sequencing as for surveillance, guidance on strain typing to guide use of subcapsular vaccines, and recognition of the importance of advocacy and awareness campaigns.


Asunto(s)
Brotes de Enfermedades/prevención & control , Infecciones Meningocócicas/epidemiología , Infecciones Meningocócicas/prevención & control , Vacunas Meningococicas/inmunología , Salud Global , Humanos , Programas de Inmunización , Incidencia , Meningitis Meningocócica/epidemiología , Meningitis Meningocócica/inmunología , Meningitis Meningocócica/prevención & control , Infecciones Meningocócicas/inmunología , Vacunas Meningococicas/uso terapéutico , Neisseria meningitidis/clasificación , Neisseria meningitidis/inmunología , Vacunas Conjugadas/inmunología , Vacunas Conjugadas/uso terapéutico
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