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1.
J Prosthet Dent ; 128(4): 814.e1-814.e10, 2022 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-36089544

RESUMEN

STATEMENT OF PROBLEM: The ceramic 5-mol% yttria-stabilized zirconia (5Y-ZP) has been developed for dental use in the esthetic zone with greater translucency than 3-mol% yttria-stabilized zirconia (3Y-ZP). However, studies on the wear behavior of 5Y-ZP zirconia against clinically relevant antagonist materials are lacking. PURPOSE: The purpose of this in vitro study was to investigate the wear behavior of 5Y-ZP zirconia against the antagonists 5Y-ZP zirconia, lithium disilicate, palladium alloy, and human enamel. MATERIALS AND METHODS: Flat specimens (n=8) were fabricated from 5Y-ZP zirconia, lithium disilicate, palladium alloy, and human central incisor enamel. A custom wear-simulating device with a sliding pin-on-plate configuration was used for a total of 120 000 wear cycles at 1.6-Hz frequency under a 49-N vertical load while submerged in distilled water at room temperature. The wear volume and maximum wear depth of flat specimens were evaluated with a 3D profilometer. Scanning electron microscopy was used to analyze the characteristics of the worn surfaces. RESULTS: After wear simulation, the 5Y-ZP zirconia and palladium-silver alloy specimens exhibited the least amount of material loss, both in terms of maximum wear depth and wear volume (0.079 ±0.042 µm, 0.001 ±0.001 mm3 and 0.637 ±0.307 µm, 0.001 ±0.000 mm3, respectively). This was followed by human enamel (6.034 ±1.086 µm, 0.009 ±0.001 mm3) and by lithium disilicate, which showed excessive material loss (38.342 ±2.569 µm, 0.213 ±0.024 mm3). Scanning electron microscopy revealed variations in wear mechanisms among the materials. CONCLUSIONS: The 5Y-ZP zirconia and palladium-silver alloy exhibited the lowest wear, followed by human enamel and lithium disilicate. Slight grain dislodgement was displayed on worn 5Y-ZP surfaces, while more apparent grain dislodgement and wear grooves were found on lithium disilicate. Plastic deformation of worn palladium-silver alloy accumulated at the end of wear track. Cracks were detected in the human enamel specimens.


Asunto(s)
Paladio , Plata , Humanos , Ensayo de Materiales , Estética Dental , Circonio , Materiales Dentales , Porcelana Dental , Cerámica , Aleaciones , Propiedades de Superficie
2.
Int J Dent ; 2022: 9341616, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35295406

RESUMEN

Objective: The wear behavior of the novel zirconia generation is less well understood and may be affected by compositional modifications compared to the conventional zirconia. Materials and Methods: Combinations of keywords such as "zirconia," "high translucent," and "wear" were searched in PubMed and Google Scholar databases up to May 2021. The total of 23 relevant articles was selected according to inclusion criteria. Results: Reports show comparable wear resistance of translucent zirconia to the conventional zirconia despite an increased cubic phase content and lower mean flexural strength. A meticulously polished surface creates the lowest surface roughness, producing favorable zirconia wear resistance and antagonist wear compared to a glazed surface. In comparison to other ceramic materials, zirconia produces the least wear on an enamel antagonist and almost undetectable wear when opposed by zirconia. Wear when paired against resin materials yields a favorable outcome, whereas wear behavior against a metal antagonist varies with the surface hardness of the metal. Conclusions: All zirconia generations are considered wear-friendly to all types of antagonists. Nonetheless, comparative studies on antagonist wear opposing zirconia of different compositions are still limited and further investigation is required.

3.
J Biomed Mater Res B Appl Biomater ; 110(2): 422-430, 2022 02.
Artículo en Inglés | MEDLINE | ID: mdl-34288380

RESUMEN

Fast acting topical hemostatic agents play a key role in hemorrhage control. Retarding fibrinolysis is also critical in improving coagulation, thereby expanding chances of survival. The purpose of the present work was to investigate the physical properties, loading capacity and hemostatic efficacy of newly developed nanoclay microsphere frameworks (NMFs) loaded with tranexamic acid (TA), as antifibrinolytic agent. Nanoclay compositions were prepared with increasing levels of TA. Results showed that TA was successfully incorporated into the nanoclay structure and released when solvated with ethanol. Both doped and undoped NMFs significantly decreased activated partial thromboplastin time and increased clot stiffness, which was attributed to significantly thinner fibrin fibers and a denser clot structure.


Asunto(s)
Hemostáticos , Ácido Tranexámico , Fibrinólisis , Hemostasis , Hemostáticos/farmacología , Microesferas , Ácido Tranexámico/farmacología
4.
J Dent Educ ; 85(5): 699-703, 2021 May.
Artículo en Inglés | MEDLINE | ID: mdl-33476060

RESUMEN

PURPOSE: Critical thinking is an essential skill for the dentist, yet little has surfaced to define the outcome, guide learning, and assess performance. On June 16, 2020, the American Dental Education Association (ADEA) sponsored a 1-hour webinar on Critical thinking with 600 attendees. To report input from a national cohort of dental educators responding to a model for critical thinking guidance. METHODS: Critical thinking concepts with explicit skillsets were presented. Attendees gave Likert responses on importance and confidence defining outcome. At the end of the webinar, attendees were asked in an open-ended format what their "take away" was. RESULTS: One hundred and five responded to a Likert scale question on how important critical thinking is, with 93% giving a 5. To the question on how well have you figured out how to define the outcome, guide learning, and assess performance, 53% gave a 3 and 21% gave a 2 (χ2  = 151; P < 0.01) From 121 "take away" responses, 79 reiterated the session's central theme with comments on emulating the thought process of the expert or articulating a skillset. In a separate classification of the same "take away," responses oriented to common domains of education nomenclature. No alternative critical thinking model for articulating the outcome, guiding learning, and assessing performance was evident in any of the 121 take away responses. CONCLUSIONS: Results are interpreted as an opportunity moment for dental education to collectively develop additional critical thinking models.


Asunto(s)
Educación en Odontología , Pensamiento , Humanos , Aprendizaje
5.
J Prosthet Dent ; 126(2): 238-247, 2021 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-32807403

RESUMEN

STATEMENT OF PROBLEM: Strengthening mechanisms of zirconia ceramics stabilized with 3 mol% yttria (3Y-TZP) are complex and dictated by the crystalline phase assemblage. Although their clinical performance for dental restorations has been excellent, there is evidence that framework fractures do occur and have been underreported. Meanwhile, the relationship between phase assemblage and reliability of 3Y-TZP is not properly understood. PURPOSE: The purpose of this in vitro study was to elucidate the relationship between crystalline phase assemblage and the reliability of 3Y-TZP and to calculate the associated probabilities of survival. MATERIAL AND METHODS: Disks of 3Y-TZP were prepared from cylindrical blanks and randomly assigned to 12 experimental groups (n=20 per group). Different crystalline phase assemblages were produced by either varying the sintering temperature from 1350 °C to 1600 °C and/or treating the surface by airborne-particle abrasion with 50-mm alumina particles at a pressure of 0.2 MPa for 1 minute with or without subsequent heat treatment. Crystalline phases were analyzed by standard and grazing incidence X-ray diffraction (GIXRD). The relationship between phase assemblage and reliability was determined by measuring the biaxial flexural strength (BFS) according to ISO standard 6872 and by using Weibull statistics to calculate the Weibull modulus (m), probability of survival, and maximum allowable stresses. XRD results were analyzed by ANOVA to detect statistically significant differences between groups. Adjustment for all pairwise group comparisons was made using the Tukey method (α=.05). RESULTS: Standard incidence XRD confirmed the presence of a small amount of cubic phase after sintering at 1350 °C. A cubic-derived nontransformable tetragonal t'-phase was observed at sintering temperatures of 1450 °C and above, the amount of which increased linearly. GIXRD revealed that airborne-particle abraded groups sintered at 1350 °C and 1600 °C had the highest variability in monoclinic phase fraction as a function of depth. These groups were also associated with the lowest reliability. Groups as-sintered at 1350 °C and 1600 °C had the lowest modulus (m=8.1 [0.5] and 7.0 [0.8], respectively) and probability of survival (Ps) for a maximum allowable stress of 700 MPa, while treated groups sintered at 1450 °C and 1550 °C were associated with the highest modulus (from 15.0 [1.4] to 20.9 [1.4]) and Ps (≥0.9999). The lower strength and reliability of groups sintered at 1600 °C was consistent with the presence of a significant amount of nontransformable t'-phase. The pattern of BFS results indicated that ferro-elastic domain switching was a dominant strengthening mechanism in 3Y-TZP. CONCLUSIONS: The present study first reported on the detrimental effect of the cubic-derived nontransformable t'-phase on the mechanical properties of 3Y-TZP. It was demonstrated that phase assemblage determined reliability and was directly linked to the probability of survival.


Asunto(s)
Materiales Dentales , Itrio , Cerámica , Ensayo de Materiales , Reproducibilidad de los Resultados , Propiedades de Superficie , Circonio
6.
J Dent Educ ; 85(3): 379-382, 2021 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-32991740

RESUMEN

A comparison of student learning in a critical thinking exercise for technology decision-making occurred with the onset of coronavirus and the switch from face-to-face to distance with Zoom. Literature on explicit critical thinking skill sets is scant in any format, including distance learning. While face-to-face and Zoom have similarities, seizing this opportunity for comparison can set the stage to determine soundness of distance learning in critical thinking on a preliminary basis. The learning outcome, learning guide and assessment instrument remained the same for the exercise in both formats; student teams presented analyses of different technologies with assessment by 2 faculty as before. Forty students had not completed the exercise when the coronavirus shut down occurred. Students performed at as high a level using virtual/Zoom as with face-to-face.


Asunto(s)
Educación a Distancia , Pensamiento , Humanos , Aprendizaje , Estudiantes , Tecnología
7.
J Biomed Mater Res B Appl Biomater ; 109(3): 328-337, 2021 03.
Artículo en Inglés | MEDLINE | ID: mdl-32815316

RESUMEN

The purpose of the present work was to investigate the effect doping with lanthanum aluminate on the phase assemblage and thermal behavior of zirconia ceramics for biomedical applications. Four compositions were prepared by a surface modification route of either conventional tetragonal zirconia (3Y-TZP) or high translucency cubic-based zirconia (5Y-PSZ) to reach a nominal composition of either 0.5 wt. % (3Y-0.5LAO and 5Y-0.5LAO) or 5 wt. % of lanthanum monoaluminate (3Y-5LAO and 5Y-5LAO). Undoped powders were used as controls. DTA and XRD analyses revealed that lanthanum dizirconate crystallized in the 934°C-936°C range, while lanthanum aluminate crystallized in the 1,056°C-1,063°C range in both types of zirconias doped at the 5% level. No second phase was found in compositions doped at the 0.5% level. The a lattice parameter and the amount of the cubic phase increased in both 3Y-5LAO and 5Y-5LAO. The microstructure of the compositions doped with 5% LAO was characterized by well distributed LAO twinned crystals and sparse needle-shaped lanthanum hexaaluminate crystals. A bimodal grain size distribution was observed in 5Y-doped compositions. This was attributed to abnormal grain growth of the cubic phase, and in line with aluminum segregation at grain boundaries and the presence of second-phase LAO crystals.


Asunto(s)
Aluminio/química , Cerámica/química , Calor , Lantano/química , Circonio/química
8.
J Biomed Mater Res B Appl Biomater ; 108(8): 3393-3401, 2020 11.
Artículo en Inglés | MEDLINE | ID: mdl-32618123

RESUMEN

Silver nanoparticles (AgNPs) have been proposed to combat oral infection due to their efficient ionic silver (Ag+ ) release. However, concentrations required for antimicrobial efficacy may not be therapeutically viable. In this work, platinum-doped silver nanoparticles (Pt-AgNPs) were explored to evaluate their potential for enhanced Ag+ release, which could lead to enhanced antimicrobial efficacy against S. aureus, P. aeruginosa, and E. coli. AgNPs doped with 0.5, 1, and 2 mol% platinum (Pt0.5 -AgNPs, Pt1 -AgNPs, and Pt2 -AgNPs) were synthesized by a chemical reduction method. Transmission electron microscopy revealed mixed morphologies of spherical, oval, and ribbon-like nanostructures. Surface-enhanced Raman scattering revealed that the surface of Pt-AgNPs was covered with up to 93% Pt. The amount of Ag+ released increased 16.3-fold for Pt2 -AgNPs, compared to AgNPs. The initial lag phase in bacterial growth curve was prolonged for Pt-AgNPs. This is consistent with a Ag+ release profile that exhibited an initial burst followed by sustained release. Doping AgNPs with platinum significantly increased the antimicrobial efficacy against all species. Pt2 -AgNPs exhibited the lowest minimum inhibitory concentrations, followed by Pt1 -AgNPs, Pt0.5 -AgNPs, and AgNPs, respectively. Doping AgNPs with a small amount of platinum promoted the release of Ag+ , based on the sacrificial anodic effect, and subsequently enhanced their antimicrobial efficacy.


Asunto(s)
Antibacterianos/farmacología , Nanopartículas del Metal , Platino (Metal)/farmacología , Plata/farmacología , Antibacterianos/química , Escherichia coli/efectos de los fármacos , Pruebas de Sensibilidad Microbiana , Nanoestructuras , Platino (Metal)/química , Pseudomonas aeruginosa/efectos de los fármacos , Plata/química , Espectrometría Raman , Staphylococcus aureus/efectos de los fármacos
9.
J Dent Educ ; 84(7): 733-741, 2020 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-32421870

RESUMEN

Critical thinking is ubiquitous in patient care. One track for critical thinking develops skillsets emulating the thought process of the master clinician using probing questions and has been offered in treatment planning, literature search, and critique, risk assessment in caries and geriatrics, technology decision-making, EBD, and IPP. This paper offers 2 additional critical thinking skillsets following this emulation model in social work and ethics. Conceptualization, another form of critical thinking, is also ubiquitous in health care, yet almost no literature exists to guide learning and assess performance on conceptualization. This paper introduces for discussion 2 examples of conceptualization-"How and how much does this situation differ from the ideal?" and "How does the student/practitioner conceptualize the outcome prior to the imminent procedure?" -used continually by the practitioner in patient care situations. The result is 4 additional critical thinking skillsets at different stages of development in the armamentarium for the teacher.


Asunto(s)
Aprendizaje , Pensamiento , Formación de Concepto , Humanos
10.
J Prosthodont ; 29(6): 534-541, 2020 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-32147893

RESUMEN

PURPOSE: To evaluate the accuracy of implant position using surgical guides fabricated by additive and subtractive techniques. MATERIALS AND METHODS: A partially edentulous standardized mandibular implant model with different bone densities and soft tissue was duplicated and a diagnostic wax-up was performed for the #30 area. A reference radiographic guide was fabricated and cone beam computed tomography (CBCT) was made with the reference radiographic guide in place. A surgical guide was designed using BlueSky Plan 4 software and a reference implant was placed in the #30 region. The STL file of the surgical guide was exported and specimens (n = 15) were fabricated by two different techniques: additive (3D printing) and subtractive (milling). The standardized mandibular model was surface-scanned and duplicated with printed dental model resin (n = 30). Each surgical guide was used to place an implant in thirty duplicate printed models. Differences in implant position as compared to the reference were measured from digital scans with scan bodies in place. The angular deviations, differences in depth, coronal and apical deviations were measured using GeoMagic Control X software. Results were analyzed by Wilcoxon-Mann-Whitney test and PERMANOVA (Permutational Multivariate Analysis of Variance). Intraclass correlation was used to assess measurement reproducibility with Bonferroni adjustment for multiple testing as needed (α = 0.05). RESULTS: There were no significant differences in accuracy of implant placement using guides fabricated using additive vs subtractive techniques. The mean angular deviations between the reference and actual position of implant in mesio-distal cross-section were 0.780 ± 0.80° for printed group and 0.77 ± 0.72° for the milled group. The differences in bucco-lingual cross-section were 1.60 ± 1.22° in in printed group and 1.77 ± 0.76° in the milled group. The differences in depth (mm) were measured at the top of the scan body at four locations: mesial, distal, buccal and lingual. The mean differences in depth for the group that used printed surgical guides were (mesial) 0.37 ± 0.29 mm, (distal) 0.32 ± 0.23 mm, (buccal) 0.24 ± 0.23 mm, and (lingual) 0.25 ± 0.17 mm. The mean differences in depth for the group that used milled surgical guides were (mesial) 0.51 ± 0.33 mm, (distal) 0.40 ± 0.32 mm, (buccal) 0.22 ± 0.23 mm, and (lingual) 0.23 ± 0.12 mm in those four aspects, respectively. The mean coronal deviation showed 0.32 mm in the printed group and 0.27 mm in the milled group. For the apical deviation, the results of this study showed mean apical deviation 0.84 mm in the printed group and 0.80 mm in the milled group. CONCLUSIONS: Results indicate that 3D-printed surgical guides are statistically as accurate as milled guides for guided-implant surgery with the benefits of high accuracy, ease of fabrication, less waste compared to subtractive techniques, and reduction of laboratory time thereby increasing cost-effectiveness.


Asunto(s)
Implantes Dentales , Cirugía Asistida por Computador , Diseño Asistido por Computadora , Tomografía Computarizada de Haz Cónico , Implantación Dental Endoósea , Imagenología Tridimensional , Reproducibilidad de los Resultados
11.
J Prosthodont ; 28(8): 927-933, 2019 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-31343801

RESUMEN

PURPOSE: To compare the use of virtual 3D casts as an alternative to paper-based exercises in preclinical removable partial denture (RPD) design in terms of student outcomes (as evidenced by exercise evaluation scores), as well as student attitudes related to the 2 formats. The first hypothesis of this study is that virtual 3D digital models in the exercise will result in better student outcomes as evidenced by the final exercise score compared to the 2D drawings. The second hypothesis is that virtual 3D digital models in the exercise will result in greater student acceptance compared to the 2D drawings. MATERIALS AND METHODS: Students were divided into 2 equal, randomly assigned groups Both groups were made to solve 2 exercises: a class II exercise and a class IV exercise. Group 1 received the first exercise (exercise #1) as a Kennedy class IV design exercise in virtual 3D and the second exercise (exercise #2) as a Kennedy class II design exercise in traditional format. Group 2 would receive the opposite exercise #1 as a Kennedy class IV in traditional format and exercise #2 as a Kennedy class II in virtual 3D format. Virtual 3D casts were made to be identical to the traditional exercises. Students were then asked to complete a short survey to assess their preferences. The Wilcoxon Rank Sum test was used to compare the distribution of scores of exercises using the virtual 3D format with the scores when students used the traditional 2D format. Preference comparisons for the 2 formats were accomplished using exact binomial tests. RESULTS: There was no difference in learning outcomes based on the distribution of student scores for either exercise independent of presentation format (p > 0.52). There was also no difference in individual student score between 2 identical exercises, independent of whether the exercise was using 3D virtual models or 2D drawings. A greater proportion of students agreed with the statements that favored the use of the virtual 3D models than disagreed with respect to all 7 questions asked, based upon the sign test (comparing agreement vs. disagreement with the statement, p < 0.0003 in all instances). CONCLUSION: Despite there being no difference in learning outcomes (final scores), the students showed an overwhelming preference in having the virtual 3D casts part as part of the curriculum.


Asunto(s)
Dentadura Parcial Removible , Curriculum , Evaluación Educacional , Humanos , Aprendizaje , Estudiantes , Encuestas y Cuestionarios
12.
J Prosthodont ; 28(2): e545-e547, 2019 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-29876996

RESUMEN

Tooth preparation for fixed dental prostheses is not an easy procedure to understand spatially, especially for first-year dental students. This technical report describes an innovative technique for assisting learning in preclinical fixed prosthodontics courses. Ideal full-contour tooth preparations are digitally scanned and 3D printed to the exact specifications of the ideal preparation. Students and faculty use these printed tooth preparations as teaching and learning tools to facilitate in 3D visualization for fixed prosthodontics courses.


Asunto(s)
Impresión Tridimensional , Prostodoncia/educación , Preparación Protodóncica del Diente/métodos , Diseño de Prótesis Dental , Humanos
13.
J Prosthodont ; 28(1): e364-e375, 2019 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-29741238

RESUMEN

PURPOSE: Chairside surface adjustments of zirconia dental restorations enhance the toughening stress-induced tetragonal-to-monoclinic phase transformation and domain reorientation by ferro-elastic domain switching (FDS), but also trigger subsurface damage, which could compromise long-term clinical performance. The purpose of this study was to assess the depth of phase transformation, associated FDS, and flexural strength of dental zirconia (BruxZir HT 2.0), after chairside surface treatments. MATERIALS AND METHODS: Square specimens were sectioned from CAD/CAM blocks and sintered according to manufacturer's recommendations (n = 30). They were left as-sintered (AS; control), air abraded with fine (AAF) or coarse (AAC) alumina particles, ground (G) or ground and polished (GP). Roughness was measured by profilometry. Crystalline phases were investigated by grazing incidence X-ray diffraction (GIXRD) (n = 3). GIXRD data were fit using semi-log regression protocols to assess transformation depth and extent of FDS. The mean biaxial flexural strength was measured according to ISO 6872. Subsurface damage was assessed from SEM images using a bonded polished interface configuration. Flaw distribution was assessed by Weibull analysis. Results were analyzed by Kruskal-Wallis with Tukey's adjustment for multiple comparisons (p < 0.05). RESULTS: Air-abraded and ground groups exhibited higher mean surface roughness than control. AAF group exhibited the highest flexural strength (1662.6 ± 202.6 MPa) with flaw size (5.9 ± 1.8 µm) smaller than transformation (14.5 ± 1.2 µm) or FDS depth (19.3 ± 1.1 µm), followed by GP group (1567.2 ± 209.7 MPa) with smallest FDS depth (9.3 ± 2.0 µm) and flaw size (2.6 ± 1.8 µm), but without m-phase. AAC group (1371.4 ± 147.6 MPa) had the largest flaw size (40.3 ± 20.3 µm), transformation depth (47.2 ± 3.0 µm) and FDS depth (41.2 ± 2.2 µm). G group (1357.0 ± 196.7 MPa) had the smallest transformation depth (8.6 ± 1.5 µm), and mean FDS depth (19.8 ± 3.7 µm) and flaw size (18.6 ± 3.1 µm). AAC and AAF exhibited the highest Weibull modulus (11.2 ± 0.4 and 9.8 ± 0.3 µm, respectively). CONCLUSIONS: Variations in mean biaxial flexural strength were explained by the balance between the depth of toughening mechanisms (phase transformation and FDS) and subsurface damage. AAF and GP groups were the most efficient surface adjustments in promoting the highest mean biaxial flexural strength.


Asunto(s)
Cerámica , Materiales Dentales , Circonio , Diseño Asistido por Computadora , Pulido Dental , Restauración Dental Permanente/métodos , Diseño de Dentadura , Resistencia Flexional , Humanos , Propiedades de Superficie
14.
Acta Biomater ; 75: 463-471, 2018 07 15.
Artículo en Inglés | MEDLINE | ID: mdl-29859366

RESUMEN

There is increasing interest in biodegradable ceramic scaffolds for bone tissue engineering capable of in situ delivery of ionic species favoring bone formation. Strontium has been shown to be osteogenic, but strontium-containing drugs such as strontium ranelate, used in Europe for the treatment of osteoporosis, are now restricted due to clinical evidence of systemic effects. By doping fluorapatite-based glasses with strontium, we developed ceramic scaffolds with fully interconnected macroporosity and cell size similar to that of cancellous bone, that are also capable of releasing strontium. The crystallization behavior, investigated by XRD and SEM, revealed the formation of akermanite and fluorapatite at the surface of strontium-free glass-ceramic scaffolds, and strontium-substituted fluorapatite at the surface of the strontium-doped scaffolds. At 8 weeks after implantation in a rat calvarial critical size defect, scaffolds doped with the highest amount of strontium led to the highest mineral apposition rate. A significantly higher amount of newly-formed bone was found with the strontium-free glass-ceramic scaffold, and possibly linked to the presence of akermanite at the scaffold surface. We demonstrate by energy dispersive XRF analyses of skull sections that strontium was present in newly formed bone with the strontium-doped scaffolds, while a significant amount of fluorine was incorporated in newly formed bone, regardless of composition or crystallization state. STATEMENT OF SIGNIFICANCE: The present work demonstrates the in vivo action of strontium-containing glass-ceramic scaffolds. These bone graft substitutes are targeted at non load-bearing bone defects. Results show that strontium is successfully incorporated in newly formed bone. This is associated with a significantly higher Mineral Apposition Rate. The benefits of in situ release of strontium are demonstrated. The broader scientific impact of this works builds on the concept of resorbable ceramic scaffolds as reservoirs of ionic species capable of enhancing bone regeneration.


Asunto(s)
Apatitas , Sustitutos de Huesos , Cerámica , Osteogénesis/efectos de los fármacos , Cráneo , Estroncio , Andamios del Tejido/química , Animales , Apatitas/química , Apatitas/farmacocinética , Apatitas/farmacología , Sustitutos de Huesos/química , Sustitutos de Huesos/farmacocinética , Sustitutos de Huesos/farmacología , Cerámica/química , Cerámica/farmacocinética , Cerámica/farmacología , Ratas , Cráneo/lesiones , Cráneo/metabolismo , Cráneo/patología , Estroncio/química , Estroncio/farmacocinética , Estroncio/farmacología
15.
J Biomed Mater Res B Appl Biomater ; 106(4): 1421-1430, 2018 05.
Artículo en Inglés | MEDLINE | ID: mdl-28636267

RESUMEN

The purpose of this work was to investigate the effect of strontium partial replacement for calcium on the crystallization behavior, microstructure and solubility of fluorapatite glass-ceramics. Four glass compositions were prepared with increasing amounts of strontium partially replacing calcium. The crystallization behavior was analyzed by differential scanning calorimetry and X-ray diffraction (XRD). The microstructure was investigated by scanning electron microscopy. The chemical solubility was quantified according to ISO standard 10993-14. The amount of strontium released in solution after incubation in TRIS-HCl or citric acid buffer was measured by atomic absorption spectroscopy. XRD analyses revealed that partially substituted strontium-fluorapatite and strontium-åkermanite crystallized after strontium additions. The lattice cell volume of both phases increased linearly with the amount of strontium in the composition. Strontium additions led to a reduction in crystal size and an increase in crystal number density. The chemical solubility and amount of strontium released in solution increased linearly with the amount of strontium present in the composition in both TRIS-HCl and citric acid buffers. Total amounts of strontium released reached a maximum of 547 ± 80 ppm in TRIS-HCl and 1252 ± 290 ppm in citric acid buffer for the glass composition with the highest amount of strontium. For all strontium-containing compositions, the amount released in TRIS-HCl continued to increase between 70 and 120 h, indicating sustained release rather than burst release. © 2017 Wiley Periodicals, Inc. J Biomater Res Part B: 106B: 1421-1430, 2018.


Asunto(s)
Apatitas/química , Cerámica/química , Estroncio , Cristalización , Preparaciones de Acción Retardada/química , Preparaciones de Acción Retardada/farmacocinética , Microscopía Electrónica de Rastreo , Solubilidad , Estroncio/química , Estroncio/farmacología , Difracción de Rayos X
16.
J Biomed Mater Res B Appl Biomater ; 106(1): 291-299, 2018 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-28135032

RESUMEN

Macroporous bioceramic scaffolds are often fabricated via the foam replica technique, based on polymeric foam impregnation with a glass slurry, followed by slow heat treatment to allow for drying, polymeric burnout, and sintering of the glass particles. As a consequence, the process is time consuming and complicated by concurrent crystallization of the glass, often leading to incomplete sintering. Our goal was to investigate the effect of heating rate on sintering behavior, architecture, and mechanical properties of fluorapatite-based glass and glass-ceramic scaffolds. Glass scaffolds were prepared and sintered by rapid vacuum sintering (RVS) at 785°C under vacuum at a fast heating rate (55°C/min.) or without vacuum at a slow heating rate (2°C/min.). Two additional groups were further crystallized at 775°C/1 h. XRD confirmed the presence of fluorapatite for crystallized scaffolds. All groups presented interconnected porosity with a pore size in the 500 µm range. Scaffolds produced by RVS exhibited an excellent degree of sintering while scaffolds produced by slow sintering were incompletely sintered. The mean compressive strength was significantly higher for the RVS groups (1.52 ± 0.55 and 1.72 ± 0.61 MPa) compared to the slow-sintered groups (0.54 ± 0.30 and 0.45 ± 0.26 MPa). Meanwhile, the total production time was reduced by more than 12 h by using the RVS technique. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 291-299, 2018.


Asunto(s)
Apatitas/química , Huesos , Cerámica/química , Ingeniería de Tejidos , Andamios del Tejido/química , Vacio
17.
J Dent Educ ; 81(8): 978-985, 2017 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-28765442

RESUMEN

Critical thinking skills are essential for the successful dentist, yet few explicit skillsets in critical thinking have been developed and published in peer-reviewed literature. The aims of this article are to 1) offer an assessable critical thinking teaching model with the expert's thought process as the outcome, learning guide, and assessment instrument and 2) offer three critical thinking skillsets following this model: for geriatric risk assessment, technology decision making, and situation analysis/reflections. For the objective component, the student demonstrates delivery of each step in the thought process. For the subjective component, the student is judged to have grasped the principles as applied to the patient or case. This article describes the framework and the results of pilot tests in which students in one year at this school used the model in the three areas, earning scores of 90% or above on the assessments. The model was thus judged to be successful for students to demonstrate critical thinking skillsets in the course settings. Students consistently delivered each step of the thought process and were nearly as consistent in grasping the principles behind each step. As more critical thinking skillsets are implemented, a reinforcing network develops.


Asunto(s)
Educación en Odontología/métodos , Evaluación Educacional , Aprendizaje , Modelos Educacionales , Estudiantes de Odontología/psicología , Pensamiento , Anciano , Toma de Decisiones Clínicas , Evaluación Geriátrica , Humanos , Medición de Riesgo
18.
Int J Prosthodont ; 28(5): 512-8, 2015.
Artículo en Inglés | MEDLINE | ID: mdl-26340012

RESUMEN

PURPOSE: The purpose of this retrospective study was to investigate the relationship of specific prosthetic complications in patients with a maxillary complete removable dental prosthesis (CRDP) opposing a mandibular metal-resin implant-fixed complete dental prosthesis (MRIFCDP) with respect to anteroposterior (AP) spread and cantilever length. MATERIALS AND METHODS: Of the 46 patients contacted for this study, 23 patients responded. All patients had been treated with a maxillary CRDP and a mandibular MRIFCDP. They were reviewed for prosthetic complications, and the AP spread and cantilever length were evaluated. A polyvinyl siloxane impression was made of each MRIFCDP so that cantilever length and AP spread could be measured. The average recall time was 8.5 years. The mechanical complications noted were screw-related complications, including both the prosthetic and the abutment screw, consisting of loosening and/or fracture, and fracture of the metal framework. Three different individuals repeated each measurement three times. Inter- and intrarater reliability was evaluated with the intraclass correlation coefficient, and a linear regression analysis of age and average cantilever length to AP spread ratio was calculated. In addition, calculations using this ratio were divided into two groups (> 2.1 and ≤ 2.1) and examined with each variable individually. A logistic regression analysis was performed for a comparison between the two AP spread ratio groups by age, right cantilever length, left cantilever length, average cantilever length, posterior spread, and failures. RESULTS: None of the predictor values was significant for the linear regression analysis of age, cantilever length, and AP ratio on number of failures. There was no significance in complications between the groups that had an AP spread ratio > 2.1 and groups that had an AP spread ratio ≤ 2.1. CONCLUSIONS: There was no statistical significance in predicting whether a screw-related complication would occur in relation to age, cantilever length, or AP spread ratio. There was no increase or decrease in complications whether the AP spread ratio was greater than or less than or equal to 2.1. In mandibular MRIFCDPs opposing maxillary complete denture situations, screw-related complications may be less likely regardless of the patient's age, cantilever length, or AP spread ratio of the prosthesis.


Asunto(s)
Prótesis Dental de Soporte Implantado , Bases para Dentadura , Diseño de Dentadura , Dentadura Completa Inferior , Dentadura Completa Superior , Adulto , Factores de Edad , Anciano , Pilares Dentales , Arco Dental/patología , Materiales de Impresión Dental/química , Técnica de Impresión Dental , Fracaso de la Restauración Dental , Femenino , Estudios de Seguimiento , Humanos , Masculino , Mandíbula/patología , Persona de Mediana Edad , Polivinilos/química , Estudios Prospectivos , Estudios Retrospectivos , Siloxanos/química
19.
J Prosthet Dent ; 113(4): 304-9, 2015 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-25488521

RESUMEN

STATEMENT OF PROBLEM: No studies have evaluated the internal adaptation of pressed and milled ceramic crowns made from digital impressions. PURPOSE: The purpose of this in vitro study was to evaluate the internal fit of pressed and milled ceramic crowns made from digital and conventional impressions. MATERIAL AND METHODS: Thirty polyvinyl siloxane (PVS) impressions and 30 Lava COS impressions made of a prepared dentoform tooth (master die) were fabricated. Thirty crowns were pressed in lithium disilicate (IPS e.max Press), and 30 crowns were milled from lithium disilicate blocks (IPS e.max CAD) (15/impression technique) with the E4D scanner and milling engine. The master die and the intaglio of the crowns were digitized with a 3-dimensional laser coordinate measurement machine. The digital master die and intaglio of each crown were merged. The distance between the die and the intaglio surface of the crown was measured at 3 standardized points. One-way ANOVA was used for statistical analysis (α=.05). RESULTS: One-way ANOVA revealed that the internal gap obtained from the Lava/press group (0.211 mm, ±SD 0.041) was significantly greater than that obtained from the other groups (P<.001), while no significant differences were found among PVS/press (0.111 mm ±SD 0.047), PVS/CAD/CAM (0.116 mm ±SD 0.02), and Lava/CAD/CAM (0.145 mm ±SD 0.024). CONCLUSIONS: The combination of the digital impression and pressed crown produced the least accurate internal fit.


Asunto(s)
Diseño Asistido por Computadora , Coronas , Técnica de Impresión Dental , Adaptación Marginal Dental , Porcelana Dental/química , Diseño de Prótesis Dental , Materiales de Impresión Dental/química , Humanos , Procesamiento de Imagen Asistido por Computador/métodos , Imagenología Tridimensional/métodos , Rayos Láser , Microscopía Confocal/métodos , Polivinilos/química , Siloxanos/química , Propiedades de Superficie , Tomografía de Coherencia Óptica/métodos
20.
J Prosthodont ; 23(8): 610-7, 2014 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-24995593

RESUMEN

PURPOSE: This in vitro study evaluated the 3D and 2D marginal fit of pressed and computer-aided-designed/computer-aided-manufactured (CAD/CAM) all-ceramic crowns made from digital and conventional impressions. MATERIALS AND METHODS: A dentoform tooth (#30) was prepared for an all-ceramic crown (master die). Thirty type IV definitive casts were made from 30 polyvinyl siloxane (PVS) impressions. Thirty resin models were produced from thirty Lava Chairside Oral Scanner impressions. Thirty crowns were pressed in lithium disilicate (IPS e.max Press; 15/impression technique). Thirty crowns were milled from lithium disilicate blocks (IPS e.max CAD; 15/impression technique) using the E4D scanner and milling engine. The master die and the intaglio of the crowns were digitized using a 3D laser coordinate measurement machine with accuracy of ±0.00898 mm. For each specimen a separate data set was created for the Qualify 2012 software. The digital master die and the digital intaglio of each crown were merged using best-fitting alignment. An area above the margin with 0.75 mm occlusal-gingival width circumferentially was defined. The 3D marginal fit of each specimen was an average of all 3D gap values on that area. For the 2D measurements, the marginal gap was measured at two standardized points (on the margin and at 0.75 mm above the margin), from standardized facial-lingual and mesial-distal digitized sections. One-way ANOVA with post hoc Tukey's honestly significant difference and two-way ANOVA tests were used, separately, for statistical analysis of the 3D and 2D marginal data (alpha = 0.05). RESULTS: One-way ANOVA revealed that both 3D and 2D mean marginal gap for group A: PVS impression/IPS e.max Press (0.048 mm ± 0.009 and 0.040 mm ± 0.009) were significantly smaller than those obtained from the other three groups (p < 0.0001), while no significant differences were found among groups B: PVS impression/IPS e.max CAD (0.088 mm ± 0.024 and 0.076 mm ± 0.023), C: digital impression/IPS e.max Press (0.089 mm ± 0.020 and 0.075 mm ± 0.015) and D: digital impression/IPS e.max CAD (0.084 mm ± 0.021 and 0.074 mm ± 0.026). The results of two-way ANOVA revealed a significant interaction between impression techniques and crown fabrication methods for both 3D and 2D measurements. CONCLUSIONS: The combination of PVS impression method and press fabrication technique produced the most accurate 3D and 2D marginal fits.


Asunto(s)
Diseño Asistido por Computadora , Coronas , Técnica de Impresión Dental , Adaptación Marginal Dental , Porcelana Dental/química , Diseño de Prótesis Dental , Técnica de Colado Dental , Materiales de Impresión Dental/química , Técnica de Impresión Dental/instrumentación , Humanos , Imagenología Tridimensional/métodos , Rayos Láser , Microscopía Confocal/métodos , Imagen Óptica/métodos , Polivinilos/química , Siloxanos/química , Propiedades de Superficie , Tomografía de Coherencia Óptica/métodos
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