1.
Org Lett
; 5(12): 2059-61, 2003 Jun 12.
Artículo
en Inglés
| MEDLINE
| ID: mdl-12790528
RESUMEN
[reaction: see text] Chloral or its hydrate undergoes the carbon-carbon bond-formation reaction with various optically active imines in the absence of any additive, followed by hydrolysis, to produce the corresponding beta-trichloromethyl-beta-hydroxy ketones in good yields with high enantioselectivities. In addition, the products with higher ee values were obtained by a simple recrystallization process.