FetSAM: Advanced Segmentation Techniques for Fetal Head Biometrics in Ultrasound Imagery.

Goal: FetSAM represents a cutting-edge deep learning model aimed at revolutionizing fetal head ultrasound segmentation, thereby elevating prenatal diagnostic precision. Methods: Utilizing a comprehensive dataset-the largest to date for fetal head metrics-FetSAM incorporates prompt-based learning. It distinguishes itself with a dual loss mechanism, combining Weighted DiceLoss and Weighted Lovasz Loss, optimized through AdamW and underscored by class weight adjustments for better segmentation balance. Performance benchmarks against prominent models such as U-Net, DeepLabV3, and Segformer highlight its efficacy. Results: FetSAM delivers unparalleled segmentation accuracy, demonstrated by a DSC of 0.90117, HD of 1.86484, and ASD of 0.46645. Conclusion: FetSAM sets a new benchmark in AI-enhanced prenatal ultrasound analysis, providing a robust, precise tool for clinical applications and pushing the envelope of prenatal care with its groundbreaking dataset and segmentation capabilities.

Locating Loneliness Through Social Intelligence Analysis.

Loneliness is a global public health issue, but the dynamics of loneliness are not understood. Through a global loneliness map, we plan to understand the dynamics of loneliness better by analyzing social media data on loneliness through social intelligence analysis. In this paper, we present the first proof of concept of the global loneliness map. Data on loneliness using keywords associated with loneliness was collected from the USA and analyzed to find meaningful associations of themes with loneliness. The NLP tool used for sentiment analysis of the tweets is a valence aware dictionary for sentiment reasoning (VADER). The tweets with negative sentiment were further analyzed for psychosocial linguistic features to find meaningful correlation between loneliness and socioeconomic and emotional themes and factors. Loneliness is subjective, hence social intelligence analysis through social media and machine learning tools can help us better understand loneliness.

Mapping loneliness through comparative analysis of USA and India using social intelligence analysis.

Loneliness, a widespread global public health concern, has far-reaching implications for mental and physical well-being, as well as economic productivity. It also increases the risk of life-threatening conditions. This study conducts a comparative analysis of loneliness in the USA and India using Twitter data, aiming to contribute to a global public health map on loneliness. Collecting 4.1 million tweets globally in October 2022 containing keywords like "lonely", "loneliness", and "alone", the analysis focuses on sentiment and psychosocial linguistic features. Utilizing the Valence Aware Dictionary for Sentiment Reasoning (VADER) for sentiment analysis, the study explores variations in loneliness dynamics across cities, revealing geographical distinctions in correlated topics. The tweets with negative sentiment were further analyzed for psychosocial linguistic features to find a meaningful correlation between loneliness and socioeconomic and emotional themes and factors. Results give detailed top correlated topics with loneliness for each city. The results showed that the dynamics of loneliness through the topics correlated vary across geographical locations. Social media data can be used to capture the dynamics of loneliness which can vary from one place to another depending on the socioeconomic and cultural norms and sociopolitical policies. Social media data to understand loneliness can also provide useful information and insight for public health and policymaking.

The metaverse digital environments: a scoping review of the challenges, privacy and security issues.

The concept of the "metaverse" has garnered significant attention recently, positioned as the "next frontier" of the internet. This emerging digital realm carries substantial economic and financial implications for both IT and non-IT industries. However, the integration and evolution of these virtual universes bring forth a multitude of intricate issues and quandaries that demand resolution. Within this research endeavor, our objective was to delve into and appraise the array of challenges, privacy concerns, and security issues that have come to light during the development of metaverse virtual environments in the wake of the COVID-19 pandemic. Through a meticulous review and analysis of literature spanning from January 2020 to December 2022, we have meticulously identified and scrutinized 29 distinct challenges, along with 12 policy, privacy, and security matters intertwined with the metaverse. Among the challenges we unearthed, the foremost were concerns pertaining to the costs associated with hardware and software, implementation complexities, digital disparities, and the ethical and moral quandaries surrounding socio-control, collectively cited by 43%, 40%, and 33% of the surveyed articles, respectively. Turning our focus to policy, privacy, and security issues, the top three concerns that emerged from our investigation encompassed the formulation of metaverse rules and principles, the encroachment of privacy threats within the metaverse, and the looming challenges concerning data management, all mentioned in 43%, 40%, and 33% of the examined literature. In summation, the development of virtual environments within the metaverse is a multifaceted and dynamically evolving domain, offering both opportunities and hurdles for researchers and practitioners alike. It is our aspiration that the insights, challenges, and recommendations articulated in this report will catalyze extensive dialogues among industry stakeholders, governmental bodies, and other interested parties concerning the metaverse's destiny and the world they aim to construct or bequeath to future generations.

Applications of discriminative and deep learning feature extraction methods for whole slide image analysis: A survey.

Digital pathology technologies, including whole slide imaging (WSI), have significantly improved modern clinical practices by facilitating storing, viewing, processing, and sharing digital scans of tissue glass slides. Researchers have proposed various artificial intelligence (AI) solutions for digital pathology applications, such as automated image analysis, to extract diagnostic information from WSI for improving pathology productivity, accuracy, and reproducibility. Feature extraction methods play a crucial role in transforming raw image data into meaningful representations for analysis, facilitating the characterization of tissue structures, cellular properties, and pathological patterns. These features have diverse applications in several digital pathology applications, such as cancer prognosis and diagnosis. Deep learning-based feature extraction methods have emerged as a promising approach to accurately represent WSI contents and have demonstrated superior performance in histology-related tasks. In this survey, we provide a comprehensive overview of feature extraction methods, including both manual and deep learning-based techniques, for the analysis of WSIs. We review relevant literature, analyze the discriminative and geometric features of WSIs (i.e., features suited to support the diagnostic process and extracted by "engineered" methods as opposed to AI), and explore predictive modeling techniques using AI and deep learning. This survey examines the advances, challenges, and opportunities in this rapidly evolving field, emphasizing the potential for accurate diagnosis, prognosis, and decision-making in digital pathology.

Large-scale annotation dataset for fetal head biometry in ultrasound images.

This dataset features a collection of 3832 high-resolution ultrasound images, each with dimensions of 959×661 pixels, focused on Fetal heads. The images highlight specific anatomical regions: the brain, cavum septum pellucidum (CSP), and lateral ventricles (LV). The dataset was assembled under the Creative Commons Attribution 4.0 International license, using previously anonymized and de-identified images to maintain ethical standards. Each image is complemented by a CSV file detailing pixel size in millimeters (mm). For enhanced compatibility and usability, the dataset is available in 11 universally accepted formats, including Cityscapes, YOLO, CVAT, Datumaro, COCO, TFRecord, PASCAL, LabelMe, Segmentation mask, OpenImage, and ICDAR. This broad range of formats ensures adaptability for various computer vision tasks, such as classification, segmentation, and object detection. It is also compatible with multiple medical imaging software and deep learning frameworks. The reliability of the annotations is verified through a two-step validation process involving a Senior Attending Physician and a Radiologic Technologist. The Intraclass Correlation Coefficients (ICC) and Jaccard similarity indices (JS) are utilized to quantify inter-rater agreement. The dataset exhibits high annotation reliability, with ICC values averaging at 0.859 and 0.889, and JS values at 0.855 and 0.857 in two iterative rounds of annotation. This dataset is designed to be an invaluable resource for ongoing and future research projects in medical imaging and computer vision. It is particularly suited for applications in prenatal diagnostics, clinical diagnosis, and computer-assisted interventions. Its detailed annotations, broad compatibility, and ethical compliance make it a highly reusable and adaptable tool for the development of algorithms aimed at improving maternal and Fetal health.

Understanding Loneliness in Younger People: Review of the Opportunities and Challenges for Loneliness Interventions.

Loneliness affects the quality of life of people all around the world. Loneliness is also shown to be directly associated with mental health issues and is often the cause of mental health problems. It is also shown to increase the risk of heart diseases and other physical illnesses. Loneliness is studied both from the social and medical sciences perspectives. There are also interventions on the basis of health informatics, information and communication technologies (ICTs), social media, and other technological solutions. In the literature, loneliness is studied from various angles and perspectives ranging from biological to socioeconomical and through anthropological understandings of technology. From the ICT and technological sides, there are multiple reviews studying the effectiveness of intervention strategies and solutions. However, there is a lack of a comprehensive review on loneliness that engulfs the psychological, social, and technological studies of loneliness. From the perspective of loneliness informatics (ie, the application of health informatics practices and tools), it is important to understand the psychological and biological basis of loneliness. When it comes to technological interventions to fight off loneliness, the majority of interventions focus on older people. While loneliness is highest among older people, theoretical and demographical studies of loneliness give a U-shaped distribution age-wise to loneliness; that is, younger people and older people are the demographics most affected by loneliness. But the strategies and interventions designed for older people cannot be directly applied to younger people. We present the dynamics of loneliness in younger people and also provide an overview of the technological interventions for loneliness in younger people. This paper presents an approach wherein the studies carried out from the perspectives of digital health and informatics are discussed in detail. A comprehensive overview of the understanding of loneliness and the study of the overall field of tools and strategies of loneliness informatics was carried out. The need to study loneliness in younger people is addressed and particular digital solutions and interventions developed for younger people are presented. This paper can be used to overcome the challenges of technological gaps in the studies and strategies developed for loneliness. The findings of this study show that the majority of interventions and reviews are focused on older people, with ICT-based and social media-based interventions showing promise for countering the effects of loneliness. There are new technologies, such as conversational agents and robots, which are tailored to the particular needs of younger people. This literature review suggests that the digital solutions developed to overcome loneliness can benefit people, and younger people in particular, more if they are made interactive in order to retain users.

Assessing the Landscape of Telehealth Interventions for Women's Health: An Umbrella Review of Recent Advances Post-Pandemic.

This umbrella review aims to provide a comprehensive overview of the use of telehealth services for women after the COVID-19 pandemic. The review synthesizes findings from 21 reviews, covering diverse topics such as cancer care, pregnancy and postpartum care, general health, and specific populations. While some areas have shown promising results, others require further research to better understand the potential of digital health interventions. The review identifies gaps in knowledge and highlights the need for more rigorous and comprehensive research to address the limitations and gaps identified in the current evidence base. This includes prioritizing the use of standardized guidelines, quality assessment tools, and meta-analyses, as well as exploring the comparative effectiveness of different digital health interventions, the experiences of specific populations, and the cost-effectiveness of these technologies. By addressing these gaps, this umbrella review can inform future research and policy decisions, ultimately improving women's health outcomes in the post-pandemic era.

Mapping loneliness through social intelligence analysis: a step towards creating global loneliness map.

OBJECTIVES: Loneliness is a prevalent global public health concern with complex dynamics requiring further exploration. This study aims to enhance understanding of loneliness dynamics through building towards a global loneliness map using social intelligence analysis. SETTINGS AND DESIGN: This paper presents a proof of concept for the global loneliness map, using data collected in October 2022. Twitter posts containing keywords such as 'lonely', 'loneliness', 'alone', 'solitude' and 'isolation' were gathered, resulting in 841 796 tweets from the USA. City-specific data were extracted from these tweets to construct a loneliness map for the country. Sentiment analysis using the valence aware dictionary for sentiment reasoning tool was employed to differentiate metaphorical expressions from meaningful correlations between loneliness and socioeconomic and emotional factors. MEASURES AND RESULTS: The sentiment analysis encompassed the USA dataset and city-wise subsets, identifying negative sentiment tweets. Psychosocial linguistic features of these negative tweets were analysed to reveal significant connections between loneliness, socioeconomic aspects and emotional themes. Word clouds depicted topic variations between positively and negatively toned tweets. A frequency list of correlated topics within broader socioeconomic and emotional categories was generated from negative sentiment tweets. Additionally, a comprehensive table displayed top correlated topics for each city. CONCLUSIONS: Leveraging social media data provide insights into the multifaceted nature of loneliness. Given its subjectivity, loneliness experiences exhibit variability. This study serves as a proof of concept for an extensive global loneliness map, holding implications for global public health strategies and policy development. Understanding loneliness dynamics on a larger scale can facilitate targeted interventions and support.

Telehealth interventions during COVID-19 pandemic: a scoping review of applications, challenges, privacy and security issues.

BACKGROUND: The COVID-19, caused by the SARS-CoV-2 virus, proliferated worldwide, leading to a pandemic. Many governmental and non-governmental organisations and research institutes are contributing to the COVID-19 fight to control the pandemic. MOTIVATION: Numerous telehealth applications have been proposed and adopted during the pandemic to combat the spread of the disease. To this end, powerful tools such as artificial intelligence (AI)/robotic technologies, tracking, monitoring, consultation apps and other telehealth interventions have been extensively used. However, there are several issues and challenges that are currently facing this technology. OBJECTIVE: The purpose of this scoping review is to analyse the primary goal of these techniques; document their contribution to tackling COVID-19; identify and categorise their main challenges and future direction in fighting against the COVID-19 or future pandemic outbreaks. METHODS: Four digital libraries (ACM, IEEE, Scopus and Google Scholar) were searched to identify relevant sources. Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) was used as a guideline procedure to develop a comprehensive scoping review. General telehealth features were extracted from the studies reviewed and analysed in the context of the intervention type, technology used, contributions, challenges, issues and limitations. RESULTS: A collection of 27 studies were analysed. The reported telehealth interventions were classified into two main categories: AI-based and non-AI-based interventions; their main contributions to tackling COVID-19 are in the aspects of disease detection and diagnosis, pathogenesis and virology, vaccine and drug development, transmission and epidemic predictions, online patient consultation, tracing, and observation; 28 telehealth intervention challenges/issues have been reported and categorised into technical (14), non-technical (10), and privacy, and policy issues (4). The most critical technical challenges are: network issues, system reliability issues, performance, accuracy and compatibility issues. Moreover, the most critical non-technical issues are: the skills required, hardware/software cost, inability to entirely replace physical treatment and people's uncertainty about using the technology. Stringent laws/regulations, ethical issues are some of the policy and privacy issues affecting the development of the telehealth interventions reported in the literature. CONCLUSION: This study provides medical and scientific scholars with a comprehensive overview of telehealth technologies' current and future applications in the fight against COVID-19 to motivate researchers to continue to maximise the benefits of these techniques in the fight against pandemics. Lastly, we recommend that the identified challenges, privacy, and security issues and solutions be considered when designing and developing future telehealth applications.

The performance of serious games for enhancing attention in cognitively impaired older adults.

Attention, which is the process of noticing the surrounding environment and processing information, is one of the cognitive functions that deteriorate gradually as people grow older. Games that are used for other than entertainment, such as improving attention, are often referred to as serious games. This study examined the effectiveness of serious games on attention among elderly individuals suffering from cognitive impairment. A systematic review and meta-analyses of randomized controlled trials were carried out. A total of 10 trials ultimately met all eligibility criteria of the 559 records retrieved. The synthesis of very low-quality evidence from three trials, as analyzed in a meta-study, indicated that serious games outperform no/passive interventions in enhancing attention in cognitively impaired older adults (P < 0.001). Additionally, findings from two other studies demonstrated that serious games are more effective than traditional cognitive training in boosting attention among cognitively impaired older adults. One study also concluded that serious games are better than traditional exercises in enhancing attention. Serious games can enhance attention in cognitively impaired older adults. However, given the low quality of the evidence, the limited number of participants in most studies, the absence of some comparative studies, and the dearth of studies included in the meta-analyses, the results remain inconclusive. Thus, until the aforementioned limitations are rectified in future research, serious games should serve as a supplement, rather than a replacement, to current interventions.

An Overview of Metabolomics Studies Based on Qatari Population.

The aim of metabolomics research is to identify the metabolites that play a role in various biological traits and diseases. This scoping review provides an overview of the current state of metabolomics studies that focus on the Qatari population. Our findings indicate that few studies have been conducted on this population, with a focus on diabetes, dyslipidemia, and cardiovascular disease. Blood samples were the primary source of metabolite identification, and several potential biomarkers for these diseases were proposed. To the best of our knowledge, this is the first scoping review that presents an overview of metabolomics studies in Qatar.

Revolutionizing Healthcare with Foundation AI Models.

ChatGPT is a foundation Artificial Intelligence (AI) model that has opened up new opportunities in digital healthcare. Particularly, it can serve as a co-pilot tool for doctors in the interpretation, summarization, and completion of reports. Furthermore, it can build upon the ability to access the large literature and knowledge on the internet. So, chatGPT could generate acceptable responses for the medical examination. Hence. It offers the possibility of enhancing healthcare accessibility, expandability, and effectiveness. Nonetheless, chatGPT is vulnerable to inaccuracies, false information, and bias. This paper briefly describes the potential of Foundation AI models to transform future healthcare by presenting ChatGPT as an example tool.

Deep Learning in Colorectal Cancer Classification: A Scoping Review.

Colorectal cancer (CRC) is one of the most common cancers worldwide, and its diagnosis and classification remain challenging for pathologists and imaging specialists. The use of artificial intelligence (AI) technology, specifically deep learning, has emerged as a potential solution to improve the accuracy and speed of classification while maintaining the quality of care. In this scoping review, we aimed to explore the utilization of deep learning for the classification of different types of colorectal cancer. We searched five databases and selected 45 studies that met our inclusion criteria. Our results show that deep learning models have been used to classify colorectal cancer using various types of data, with histopathology and endoscopy images being the most common. The majority of studies used CNN as their classification model. Our findings provide an overview of the current state of research on deep learning in the classification of colorectal cancer.

A Deep Learning-Based Approach Towards Simultaneous Localization of Optic Disc and Fovea from Retinal Fundus Images.

In this work, we propose a multi-task learning-based approach towards the localization of optic disc and fovea from human retinal fundus images using a deep learning-based approach. Formulating the task as an image-based regression problem, we propose a Densenet121-based architecture through an extensive set of experiments with a variety of CNN architectures. Our proposed approach achieved an average mean absolute error of only 13pixels (0.04%), mean squared error of 11 pixels (0.005%), and a root mean square error of only 0.02 (13%) on the IDRiD dataset.

Optical Disc Segmentation from Retinal Fundus Images Using Deep Learning.

The optical disc in the human retina can reveal important information about a person's health and well-being. We propose a deep learning-based approach to automatically identify the region in human retinal images that corresponds to the optical disc. We formulated the task as an image segmentation problem that leverages multiple public-domain datasets of human retinal fundus images. Using an attention-based residual U-Net, we showed that the optical disc in a human retina image can be detected with more than 99% pixel-level accuracy and around 95% in Matthew's Correlation Coefficient. A comparison with variants of UNet with different encoder CNN architectures ascertains the superiority of the proposed approach across multiple metrics.

Predicting Overall Survival in METABRIC Cohort Using Machine Learning.

Triple-negative breast cancer (TNBC) is an aggressive form of breast cancer that presents very high relapse and mortality. However, due to differences in the genetic architecture associated with TNBC, patients have different outcomes and respond differently to available treatments. In this study, we predicted the overall survival of TNBC patients in the METABRIC cohort employing supervised machine learning to identify important clinical and genetic features that are associated with better survival. We achieved a slightly higher Concordance index than the state of art and identified biological pathways related to the top genes considered important by our model.

Using AI for Detection, Prediction and Classification of Retinal Detachment.

The current state of machine learning (ML) and deep learning (DL) algorithms used to detect, classify and predict the onset of retinal detachment (RD) were examined in this scoping review. This severe eye condition can cause vision loss if left untreated. By analyzing the medical imaging modalities such as fundus photography, AI could help to detect peripheral detachment at an earlier stage. We have searched five databases: PubMed, Google Scholar, ScienceDirect, Scopus, and IEEE. Two reviewers independently carried out the selection of the studies and their data extractions. 32 studies fulfilled our eligibility criteria from the 666 references collected. In particular, based on the performance metrics employed in these studies, this scoping review provides a general overview of emerging trends and practices concerning using ML and DL algorithms for detecting, classifying, and predicting RD.

Scoping Review: Legal and Ethical Principles of Artificial Intelligence in Public Health.

The growing accessibility of large health datasets and AI's ability to analyze them offers significant potential to transform public health and epidemiology. AI-driven interventions in preventive, diagnostic, and therapeutic healthcare are becoming more prevalent, but they raise ethical concerns, particularly regarding patient safety and privacy. This study presents a thorough analysis of ethical and legal principles found in the literature on AI applications in public health. A comprehensive search yielded 22 publications for review, revealing ethical principles such as equity, bias, privacy, security, safety, transparency, confidentiality, accountability, social justice, and autonomy. Additionally, five key ethical challenges were identified. The study emphasizes the importance of addressing these ethical and legal concerns and encourages further research to establish comprehensive guidelines for responsible AI implementation in public health.

The Pros and Cons of Using ChatGPT in Medical Education: A Scoping Review.

This scoping review explores the advantages and disadvantages of using ChatGPT in medical education. We searched PubMed, Google Scholar, Medline, Scopus, and Science Direct to identify relevant studies. Two reviewers independently conducted study selection and data extraction, followed by a narrative synthesis. Out of 197 references, 25 studies met the eligibility criteria. The primary applications of ChatGPT in medical education include automated scoring, teaching assistance, personalized learning, research assistance, quick access to information, generating case scenarios and exam questions, content creation for learning facilitation, and language translation. We also discuss the challenges and limitations of using ChatGPT in medical education, such as its inability to reason beyond existing knowledge, generation of incorrect information, bias, potential undermining of students' critical thinking skills, and ethical concerns. These concerns include using ChatGPT for exam and assignment cheating by students and researchers, as well as issues related to patients' privacy.