Eye movement analysis using a binocular video-ophthalmoscope.

This paper describes an application of binocular video-ophthalmoscope for binocular eye movement analysis during target fixation. We analyze eye movements during monocular and binocular fixation and the changes in eye position for 73 subjects. We show that the standard deviations of differences between eye shifts for vertical and horizontal movements are higher for binocular fixation with respect to monocular fixation. We also present different examples of eye movement visualization.

Blind Source Separation of Different Retinal Pulsatile Patterns from Simultaneous Long-term Binocular Ophthalmoscopic Video-records.

Optical imaging of retinal hemodynamic function is an important part of ophthalmologic research. Development and inventing of imaging devices and data analysis methods are both just in progress. The current study innovatively implements two blind source separation (BSS) techniques (i.e. spatial Principal Component Analysis - sPCA; and spatial Independent Component Analysis - sICA) in application of an automatic detection and segmentation of a distinct Optic Disc (OD) areas with different hemodynamic properties from a simultaneous binocular video-ophthalmoscopic records. Both methods detected 3 different spatial patterns mostly symmetric over both eyes stable and reproducible over investigated participants, i.e. central Spontaneous Vessel Pulsations (SVPs), inner OD intensity pulsations and other OD pulsations. Dynamics of all mentioned patterns has a periodic character with similar main frequency (possibly corresponding to subject-specific heart rate) but shifted phase decreasing patterns' mutual high cross-correlations. The sICA estimates a higher rate of phase shifts than sPCA.