[Observations of the non-surgical treatment response on diabetic patients with chronic periodontitis].

PURPOSE: To observe the non-surgical treatment response on diabetic patients with chronic periodontitis. METHODS: Moderate to advanced chronic periodontitis was studied in 36 Diabetes Mellitus (DM) patients classified as 20 cases with high and fluctuating blood glucose level (DM-H) and 16 cases with relatively low and stable blood glucose level (DM-L). 28 non-DM patients with chronic periodontitis served as control (Non-DM). Plaque Index (PlI), Gingival Index (GI), Bleeding on Probing (BOP), Probing Depth (PD) and Clinical Attachment Loss (AL) of all patients were recorded at 6 sites on each tooth at the baseline and in the first, the third, the sixth month after oral hygiene instrument (OHI), scaling and root planing. RESULTS: It was found that the short-term effect of non-surgical periodontal procedure had resulted in significant resolution of gingival inflammation and pronounced reduction in pocket depth and gain of attachment loss in all patients. The treatment response was similar in both DM and Non-DM patients with chronic periodontitis. CONCLUSIONS: Non-surgical periodontal treatment allowed for favorable treatment responses in a group of diabetic patients with chronic periodontitis and that their various profiles of blood glucose did not influence the short-term healing response to the treatment.

[A clinical study of doxycycline slow-release gel on periodontitis chemotherapy].

OBJECTIVE: To observe the effect of Doxycycline slow-release on periodontitis therapy. METHODS: 30 patients with chronic periodontitis were chosen and divided into 2 groups randomly,these cases were given Doxycycline slow-release and Zinciodati Comp solution. PLI,GI,SBI,PD,AL,MD and clinical symptoms were observed before and after taking drug. RESULTS: The indose of PLI,GI,SBI,PD,AL,MD were decreased significantly after the use of Doxycycline slow-release gel (P<0.05),the effects of the Doxycycline was better than Zinciodati Comp solution (P<0.01), no adverse drug side effects were found during trial. CONCLUSION: The use of Doxycycline slow-release gel is one of the safe and effective chemotherapy on periodontitis.