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2.
Nat Mater ; 11(5): 455-9, 2012 Apr 01.
Artículo en Inglés | MEDLINE | ID: mdl-22466747

RESUMEN

Coherent Diffractive Imaging (CDI) is an algorithmic imaging technique where intricate features are reconstructed from measurements of the freely diffracting intensity pattern. An important goal of such lensless imaging methods is to study the structure of molecules that cannot be crystallized. Ideally, one would want to perform CDI at the highest achievable spatial resolution and in a single-shot measurement such that it could be applied to imaging of ultrafast events. However, the resolution of current CDI techniques is limited by the diffraction limit, hence they cannot resolve features smaller than one half the wavelength of the illuminating light. Here, we present sparsity-based single-shot subwavelength resolution CDI: algorithmic reconstruction of subwavelength features from far-field intensity patterns, at a resolution several times better than the diffraction limit. This work paves the way for subwavelength CDI at ultrafast rates, and it can considerably improve the CDI resolution with X-ray free-electron lasers and high harmonics.


Asunto(s)
Procesamiento de Imagen Asistido por Computador/métodos , Difracción de Rayos X/métodos , Algoritmos , Procesamiento de Imagen Asistido por Computador/estadística & datos numéricos , Difracción de Rayos X/estadística & datos numéricos
3.
Health Aff (Millwood) ; 20(4): 43-56, 2001.
Artículo en Inglés | MEDLINE | ID: mdl-11463089

RESUMEN

The growth of managed care in the United States has been paralleled by a rising tide of anti-managed care sentiment. The "managed care problem" is understood generally as the need to protect individuals against large companies that care more about their bottom line than about people. The premise of the BEST (Best Ethical Strategies for Managed Care) project is that the "managed care problem" is best understood as an ethical problem--a conflict of values that arises as the country changes from a patient-centered to a population-centered approach to health care. The BEST project team worked with nine managed care organizations to identify their most intractable problems. The team redefined these problems in terms of ethical dilemmas, then studied each organization in search of innovative, exemplary approaches. These exemplary approaches are being shared publicly with the aim that they be adapted and adopted by other organizations facing similar difficulties and by regulators and legislators hoping to improve the health care system.


Asunto(s)
Ética Institucional , Programas Controlados de Atención en Salud/normas , Benchmarking , Confidencialidad , Humanos , Programas Controlados de Atención en Salud/legislación & jurisprudencia , Objetivos Organizacionales , Poder Psicológico , Calidad de la Atención de Salud , Estados Unidos
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