[The course on the longevity of the population: the problem and the prospect.]

The demographic situation of the Russian Federation is characterized by an aging population, which is a new challenge to achieve active and healthy longevity. The purpose of the study is to identify the factors influencing the increase in active longevity based on the results of the analysis of statistical data on the proportion of people over 60 years of age and life expectancy and sociological studies. On the basis of official statistics, the analysis of life expectancy, the proportion of people over 60 years old was carried out. The obtained data of the sociological study revealed that in order for the Russian Federation to follow the course of increasing active and healthy longevity, it must focus on the determinants of socio-economic character. On the basis of the age-shifting method, the forecast of the proportion of people over 60 years old was carried out (using the example of one of the regions of the Russian Federation). The Center for Family and Demography of the Academy of Sciences of the Republic of Tatarstan has developed recommendations for achieving active and healthy longevity, which are presented in the annual Demographic report of the Republic of Tatarstan, by improving health and reducing mortality.

[Heart reHeart remodeling in patients with severe systolic dysfunction due tocancer chemotherapymodeling in patients with severe systolic dysfunction due tocancer chemotherapy.]

Objective Comparative analysis of structural and functional specific features of the heart in patients with toxic cardiomyopathy (TCMP) with a low left ventricular ejection fraction (LVEF) and severe, chronic heart failure (CHF) and in patients with idiopathic dilated cardiomyopathy (DCMP) and similar LVEF and CHF severity.Materials and Methods This observational, single-site study included 15 patients with TCMP (12 of them received treatment including anthracycline antibiotics and 3 patients received targeted therapies) and 26 patients with idiopathic DCMP. Data of echocardiography were compared for patients with TCMP and DCMP with comparably low LVEF of <40 %.Results In patients with severe heart damage associated with antitumor therapy with low LVEF, volumetric and linear indexes of left and right ventricles and the left atrium (left atrial volume index (LAVI), 33.7 (21.5-36.9) ml / m2; right ventricular end-diastolic dimension (RVDd), 2.49 (1.77-3.53) cm; and end-diastolic volume index (EDVI), 78.0 (58.7-90.0) ml / m2) were considerably less than in the DCMP group (LAVI, 67.1 (51.1-85.0) ml / m2; RVDd, 4.05 (3.6-4.4) cm; and EDVI, 117.85 (100.6-138.5) ml / m2, p<0.0001). Furthermore, LV wall thickness and pulmonary artery systolic pressure did not differ in these groups. Both in men and women with TCMP, LAVI and EDVI were significantly less than in men and women with DCMP.Conclusion The study showed significant differences in parameters of cardiac remodeling. In TCMP patients as distinct from DCMP patients, despite a pronounced decrease in LVEF, LV dilatation was absent or LV volumetric parameters were moderately increased with a more severe somatic status.

[Isolation of Campylobacter fetus from persons with obstetric-gynecological infections].

Campylobacter fetus subspecies fetus is a cause of different obstetric-gynecological diseases. It is a first time when rate of infection with Campylobacter was studied and connection between the infection and development of chronic gynecologic diseases and pathology of labor was established. Bacteria were isolated and identified in 36.0% +/- 0.7 of studied women admitted to inpatient clinics. It was established that Campylobacter fetus subspecies fetus can cause abnormalities in placenta functions as well as different inflammatory processes during pregnancy.