[Investigation of the Correlation between Patient Characteristics and Contrast Enhancement during Hepatic Dynamic CT Scan: Comparison by the Sex].

The purpose of this study was to investigate the correlation between patient characteristics and contrast enhancement during the hepatic arterial phase (HAP) and portal venous phase (PVP) CT scanning. All were examined using a hepatic dynamic CT protocol; the scanning parameters were tube voltage 120 kVp, tube current 50 to 600 mA (noise index 8.0 HU), 0.5-s rotation, 5-mm detector row width, 0.813 or 0.825 beam pitch, and the contrast material 600 mg/kg iodine. We calculated contrast enhancement (per gram of iodine: ΔHU/gI) of the abdominal aorta during the HAP and that of the hepatic parenchyma during the PVP. There was a significant difference in the contrast enhancement of the abdominal aorta during the HAP (8.6±2.7 ΔHU/gI) and (9.5±1.7 ΔHU/gI) and that of the hepatic parenchyma during the PVP (1.4±0.5 ΔHU/gI) and (2.9±0.5 ΔHU/gI) between male and female patients (p<0.05). A significant positive correlation was seen between the ΔHU/gI of aortic enhancement and age in male and female patients (r=-0.382 and 0.213) (p<0.05). A significant inverse correlation was observed between the ΔHU/gI of aortic enhancement and the height (HT; r=-0.466 and -0.251), total body weight (TBW; r=-0.609 and -0.535), body mass index (BMI; r=-0.505 and -0.465), lean body weight (LBW; r=-0.642 and -0.576), and body surface area (BSA; r=-0.644 and -0.557) (p<0.05 for all) in male and female patients. A significant positive correlation was seen between the ΔHU/gI of hepatic parenchymal enhancement and the patient age in male and female patients (r=0.258 and 0.150) (p<0.05). A significant inverse correlation was observed between the ΔHU/gI of hepatic parenchymal enhancement and the HT (r=-0.487 and -0.321), TBW (r=-0.580 and -0.525), BMI (r=-0.473 and -0.413), LBW (r=-0.615 and -0.576) (p<0.05 for all), and BSA (r=-0.617 and -0.558) in male and female patients. The BSA was significantly correlated with the ΔHU/gI of aortic and hepatic parenchymal enhancement of the hepatic dynamic CT in male patients. However, LBW was significantly correlated with the ΔHU/gI of aortic and hepatic parenchymal enhancement of the hepatic dynamic CT in female patients. Since the patient factors that affect the contrast enhancement of the abdominal aorta and hepatic parenchyma may differ from facility to facility, we should therefore consider reassessing at each facility.

COMPARISON OF THE 64- AND 80-DETECTOR ROW COMPUTED TOMOGRAPHY AMONG THE CT NUMBER AND RADIATION DOSE DURING LOWER EXTREMITY COMPUTED TOMOGRAPHY ANGIOGRAPHY.

To compare the computed tomography (CT) number and the radiation dose between the 64 (group A) and 80-detector row (group B) during lower extremity computed tomography angiography (LE-CTA). We enrolled 144 patients underwent LE-CTA and compared the CT number for the popliteal arteries, radiation dose and the rate of the optimal CT number during the LE-CTA exceeding 200 HU between the two groups. The CT number for the popliteal arteries and mean dose-length product was significantly higher in Group A than in Group B (P < 0.01). The rate of the optimal CT number for the popliteal arteries was 23.6% with Group B scanner and 56.9% with Group A (P < 0.05). The 64-detector row CT was significantly higher in the CT number for the popliteal arteries, radiation dose and rate of the optimal CT number during the LE-CTA than the 80-detector row. Depiction ability did not improve by using a high CT scanner with a wider detector during LE-CTA.

[SNR Estimation for Image Quality Evaluation in X-ray CT].

PURPOSE: Although the signal-to-noise ratio (SNR) currently used in the field of medical X-ray CT is utilized for local image evaluation in a linear system, it is not used as a comprehensive evaluation index for an entire image. Additionally, since X-ray CT cannot produce a noiseless image for obtaining the signal power required to calculate the SNR, it is impossible to calculate SNR precisely even applying the conventional method. To resolve these problems, we propose SNR*, which is a new method for calculating the estimated value of SNR that can evaluate an entire image even when the original image cannot be obtained. METHODS: First, we obtained SNR* using the signal power and noise power calculated respectively from covariance and the difference in the pair of observed images, which are noise-containing images scanned under the same imaging conditions. Next, we verified the error and the accuracy of SNR*. Third, we demonstrated the behavior and accuracy of the SNR* applied to the actually observed image. RESULTS: In the verification experiment, the relative error of SNR* concerning the true value was 0.06% or less, and the coefficient of variation value of SNR* in the demonstration experiment was 0.015 or less, which denoted the accuracy of SNR*. CONCLUSION: The proposed method realizes SNR measurement even in cases in which only observed images can be obtained and original images cannot be obtained, such as X-ray CT images.

[Experiment of a Dedicated Lead Slit for X-ray Output Analyzer in X-ray CT Half-value Layer Measurements].

It is not easy to measure the half-value layer (HVL) of CT because it is necessary to place the X-ray tube position fixed. The aim of this study was to experiment the new methods of HVL measuring of CT using a custom-made lead slit. The custom-made lead slit method allowed the HVL measuring of CT while the rotation of the X-ray tube. The error of HVL value using the custom-made lead slit method compared to the conventional method was within 6%. The custom-made lead slit method can enable to measure the HVL of CT easily without the X-ray tube position fixed.

Relationship between transient severe motion of the liver in gadoxetic acid or iodinated contrast agent-enhanced imaging and arterial oxygen saturation and heart rate changes.

PURPOSE: To clarify the relationship between transient sever motion artifact in arterial phase (TSMA) and changes in peripheral capillary oxygen saturation (SpO2) and heart rate (HR) after contrast media administration during MRI or CT of the liver. METHODS: 87 patients undergoing 61 MRI examination with gadoxetic acid or 26 CT examination with iodinated contrast were included. Dynamic contrast-enhanced imaging (DCEI) was obtained at four vascular phase acquisitions. Reviewers extracted the segmental data of SpO2 and HR in each phase from consecutive data in DCE-CT or DCE-MRI. In addition, reviewers scored for respiratory motion in each phase using 5-point scale. Patients with an arterial score of 4-5, and other phase scores of 1-2 were considered to be exhibiting TSMA. RESULTS: In gadoxetic acid, mean SpO2 of arterial phase was significantly lower than three other phases (P = 0.045 to P < 0.001). However, the decrease in SpO2 in arterial phase compared with other phases was <1%. Mean HR in gadoxetic acid or iodinated contrast agent was highest in the portal-phase. The incidence of TSM was 0% in patients with iodinated contrast agent and was 8.2% (5/61 patients; TSM group) in patients with gadoxetic acid, respectively. In addition, there was no significant difference in mean SpO2 of arterial phase between the TSM group (97.5% ±â€¯1.08%) and non-TSM group (96.4% ±â€¯1.85%) (P = 0.219). CONCLUSION: The slight decrease in SpO2 in arterial phase is not associated with TSMA.

[Assessment of the exposure dose value displayed on operator console in a computed tomography system deciding exposure dose from positioning image].

The aim of this study was to assess the exposure dose value (DLP) displayed on the operator console in a computed tomography system with automatic exposure control (CT-AEC) which decides the exposure dose from a positioning image. We measured exposure dose with two kinds of CT systems and evaluated the error of the displayed DLP value on the operator console against the measured DLP value. The assessment was performed in three sites: head and neck, upper chest, and lower abdomen. As a result, the errors of displayed value with CT-AEC against the error without CT-AEC in system A (4.09%) were significantly different on two assessment sites (head and neck: -4.02%, upper chest: 6.60%). There is no significant difference on the third assessment site (lower abdomen: 0.06%). On the other hand, those values in system B (8.38%) were almost similar with no significant differences (head and neck: -1.12%, upper chest: -1.85%, lower abdomen: -0.64%). The results show that there were significant differences noted between the errors of displayed value with CT-AEC and without CT-AEC in system A for the head and neck and the upper chest. In conclusion, displayed value with CT-AEC and without CT-AEC were about the same error. However, the possibility that the error depended on a model and the examination site of CT was shown.

The endoscopically measured effects of airway maneuvers and the lateral position on airway patency in anesthetized children with adenotonsillar hypertrophy.

Obstruction of the upper airway is a major challenge for anesthesiologists administering general anesthesia in spontaneously breathing children with adenotonsillar hypertrophy. Lateral positioning is a simple treatment for obstructive sleep apnea. In this study, we examined the effects of body position shifting and common airway maneuvers such as chin lift and jaw thrust on airway patency (stridor score and upper airway dimensions by endoscopy) in anesthetized children scheduled for adenotonsillectomy. Eighteen children aged 1-11 yr were anesthetized with sevoflurane. During spontaneous breathing with 5% sevoflurane and 100% oxygen, upper airway dimensions and stridor score were recorded. After baseline recording, chin lift and jaw thrust were performed in both the supine and the lateral decubitus position. Chin lift, jaw thrust, and lateral position increased the airway dimensions and improved the stridor score. Moreover, lateral positioning enhanced the effects of these airway maneuvers on airway patency. We concluded that lateral positioning combined with airway maneuvers provided better airway patency for anesthetized children with adenotonsillar hypertrophy.