[Vaping and vaping-associated lung injury: A review].

Vaping, i.e. the use of electronic nicotine/other substances delivery systems, increases a risk of vaping-associated lung injury. The review describes clinical manifestation, methods of diagnosis and diagnostic criteria, treatment of patients with this disease as well as risk stratification of vapers and approaches to their management based on Worchester classification and clinical guidance. The pathogenetic mechanisms of vaping-associated lung injury have been analyzed.

Difficulties in Goodpasture's syndrome diagnosing.

The article analyzes the diagnosis and treatment of anti-GBM antibody disease (Goodpasture's syndrome) - a rare, severe progressive disease, associated with anti-glomerular basement membrane antibody-induced pulmonary hemorrhage and glomerulonephritis. The main problem of this pathology is late diagnosis, resulted in ineffective treatment. The article provides current information on the epidemiology, etiology and pathogenesis, diagnosis, and treatment of Goodpasture's syndrome, as well as clinical case of a patient with this rare disease.

[Comparative characteristic of the hormonal profile in men with stable obstructive pulmonary disease and smokers].

Comparative analysis of the hormonal profile was performed in 12 and 16 patients with mild and moderately severe chronic obstructive pulmonary disease (COPD) respectively, in 25 patients with chronic bronchitis, 13 smokers without respiratory symptoms and dysfunction of external respiration, and in healthy non-smokers. Patients with moderately severe COPD had lower concentrations of total and free testosterone and DHEA than smokers with chronic bronchitis and mild COPD. Blood androsterone level positively correlated with the forced expiratory volume during the first second and inversely related to the duration of smoking and severity of coughing.

[Myocardial inotropic function in patients with chronic obstructive lung diseases as evidenced by biventricular equilibrium ventriculography]. / Sostoianie inotropnoi funktsii miokarda u bol'nykh khronicheskimi obstruktivnymi bolezniami legkikh po dannym biventrikuliarnoi ravnovesnoi vebtrikulografii.

At present chronic obstructive lung diseases (COLD) occupy a prominent place in the morbidity and mortality of the adult population, with regarding the more and more increasing influence of aggressive environmental factors (sulfur dioxide, nitrogen, ozone, black smog and smoking). Due to the fact that clinical symptoms develop in patients with COLD at its late stages when there are irreversible changes in not only the bronchopulmonary apparatus, but, to a greater extent, the cardiovascular system; the efficiency of performed therapy is rather little. This shows it necessary to diagnose myocardial contractile disorders in such patients as soon as possible as the routine accessible cardiac study techniques (ECG, EchoCG) are of low informative value due to significant emphysema. In this view, of particular value is the use of radionuclide studies, including biventricular equilibrium radionuclide ventriculography that provides adequate information on the status of both ventricles.

[Aerophytotherapy with olesan oil in the treatment of patients with chronic obstructive bronchitis and bronchial asthma]. / Aérofitoterapiia olesan-oil v lechenii bol'nykh khronicheskim obstruktivnym bronkhitom i bronkhial'noi astmoi.

Positive clinical changes were found in 28 (64%) of 44 patients with chronic obstructive pulmonary diseases (COPD) treated with olesan-oil as aerophytotherapy. These patients improved also external respiration function.

[Evaluation of clinical effectiveness of intravenous laser irradiation of blood, plasmapheresis and their combination in patients with bronchial asthma]. / Izuchenie klinicheskoi éffektivnosti vnutrivennogo lazernogo oblucheniia krovi, plazmafereza i ikh sochetaniia u bol'nykh bronkhial'noi astmoi.

AIM: To compare clinical response to intravenous laser radiation of blood (ILRB), plasmapheresis (PA) and ILRB + PA in patients with bronchial asthma (BA). MATERIALS AND METHODS: 122 patients with endogenic BA of moderate severity were divided into four groups: group 1 was exposed to ILRB, group 2--to PA, group 3--to ILRB + PA, group 4 received only chemotherapy. The effect was assessed by body plethismography, peak flowmetry, NBT-test, LCP-test. RESULTS: Patients of group 1-3 vs group 4 demonstrated earlier disappearance of cough and normalization of lung auscultative picture, lower demand of oral glucocorticosteroids, 2 times longer remission, better external respiration function, earlier normalization of peak expiration flow. ILRB, PA and ILRB + PA activate function of oxygen-dependent bactericidal system of blood neutrophils and inhibited activity of non-oxygen-dependent system. CONCLUSION: Combined treatment of moderate severity BA with ILRB, PA alone and in combination is more effective than conventional drug therapy, the highest effect by remission terms being achieved in combination of ILRB with PA.