Brain functional connectivity in children with a mild traumatic brain injury: A scoping review.

INTRODUCTION: The occurrence of mild traumatic brain injury(mTBI) is estimated at 0,2-0,3% cases annually. Following a mTBI, some children experience persistent symptoms, and functional connectivity(FC) changes may be implicated. However, characteristics of FC have not been widely described in this population. This scoping review aimed to identify and understand the impacts of mTBI on EEG-measured FC in children, provide an overview of the available literature, detail analysis techniques, and describe gaps in the research. METHODS: PubMed, Web of Science, Medline, Embase, ProQuest and CINAHL were searched up to June 25, 2023, with the terms child, mTBI, EEG, FC, and their synonyms. Ten studies were identified. RESULTS: Five studies reported significant differences between the mTBI group and controls. In addition to group differences, six studies reported significant variation over time. Brain Network Analysis(BNA), utilized in seven studies, was the primary FC analysis recorded. Two of the five studies that reported significant differences following mTBI utilized the BNA. The other three applied alternative analysis methods. DISCUSSION: FC assessment based on EEG can identify some differences in children with mTBI. BNA was more useful in following changes over time. Further research is suggested, considering the limited age range and number of retrieved studies.

Preserved category-based inferences for word learning in school-aged children with developmental language disorder.

Word learning difficulties are often found in children with Developmental Language Disorder (DLD). Lexical patterns of difficulties appear to be well described in the context of DLD but very little research focuses on their underlying causes. Word learning is known to be an inference-based process, constrained by categorization, which helps the extension of new words to unfamiliar referents and situations. These processes appear integrated in Bayesian models of cognition, which supposes that learning relies on an inductive inference process that recruits prior knowledge and principles of statistical learning (detection of regularities). Taken together, these mechanisms remain underexplored in DLD. Our study aims to define whether children with DLD can draw inductive inferences in a word learning context using categorization. Twenty children with DLD (between 6;0 and 12;6), and 20 language-matched and 16 age-matched controls were exposed to a word learning task where they were given exemplars of objects associated with pseudo-words. The objects belonged to six categories spread across three hierarchical levels. For each item, the children chose which one(s), among a set of test objects from the same categories, could be labelled the same way (word extension). Results showed that school-aged children with DLD could extend new words to broader categories as well as their typically developing (TD) peers. Nevertheless, none of the DLD or TD children showed a specification of their categorization of familiar instances that referred to more restricted instances. Our study suggests preserved abilities in using conceptual knowledge in order to learn new words, which could be used as a compensative strategy in the context of therapy. Further studies are needed to investigate this ability in more complex learning contexts.

Influence of dance training on challenging postural control task.

BACKGROUND: Previous studies have shown that dance training affects postural control, particularly during challenging tasks. However, it is still unknown whether dance training also affects the ability to use vestibular, somatosensory, and visual cues, thus leading to postural control differences. OBJECTIVE: The main goal of the present study was to evaluate the influence of dance training on sensory weighting during static postural control. METHOD: The center of pressure of 24 participants was recorded (12 dancers and 12 control non-dancers) using a force platform as well as the modified Clinical Test of Sensory Organization in Balance (mCTISB). RESULTS: The results suggest that dancers perform significantly better than controls in conditions where somatosensory cues are disturbed. Moreover, a significant negative correlation between vestibular frequency band and training intensity was observed, along with, a significant positive correlation between visual frequency band and training intensity. SIGNIFICANCE: This research outlines dancers' increased ability to modulate sensory weighting differently than non-dancers during postural task where somatosensory cues are reduced.

Parameters of semantic multisensory integration depend on timing and modality order among people on the autism spectrum: evidence from event-related potentials.

Individuals with autism spectrum disorders (ASD) report difficulty integrating simultaneously presented visual and auditory stimuli (Iarocci & McDonald, 2006), albeit showing enhanced perceptual processing of unisensory stimuli, as well as an enhanced role of perception in higher-order cognitive tasks (Enhanced Perceptual Functioning (EPF) model; Mottron, Dawson, Soulières, Hubert, & Burack, 2006). Individuals with an ASD also integrate auditory-visual inputs over longer periods of time than matched typically developing (TD) peers (Kwakye, Foss-Feig, Cascio, Stone & Wallace, 2011). To tease apart the dichotomy of both extended multisensory processing and enhanced perceptual processing, we used behavioral and electrophysiological measurements of audio-visual integration among persons with ASD. 13 TD and 14 autistics matched on IQ completed a forced choice multisensory semantic congruence task requiring speeded responses regarding the congruence or incongruence of animal sounds and pictures. Stimuli were presented simultaneously or sequentially at various stimulus onset asynchronies in both auditory first and visual first presentations. No group differences were noted in reaction time (RT) or accuracy. The latency at which congruent and incongruent waveforms diverged was the component of interest. In simultaneous presentations, congruent and incongruent waveforms diverged earlier (circa 150 ms) among persons with ASD than among TD individuals (around 350 ms). In sequential presentations, asymmetries in the timing of neuronal processing were noted in ASD which depended on stimulus order, but these were consistent with the nature of specific perceptual strengths in this group. These findings extend the Enhanced Perceptual Functioning Model to the multisensory domain, and provide a more nuanced context for interpreting ERP findings of impaired semantic processing in ASD.

Alternative mode of presentation of Kanizsa figures sheds new light on the chronometry of the mechanisms underlying the perception of illusory figures.

The mechanisms responsible for the perception of illusory modal figures are usually studied by presenting entire Kanizsa figures at stimulus onset. However, with this mode of presentation, the brain activity generated by the inducers (the 'pacmen') is difficult to differentiate from the activity underlying the perception of the illusory figure. Therefore, in addition to this usual presentation mode, we used an alternative presentation mode. Inducer disks remained permanently on the screen and the illusory figure was induced by just removing the notches from the disks. The results support the heuristic value of this alternative mode of presentation. The P1 deflection of the visual evoked potentials (VEPs) was found to be greater for the illusory modal figure than for its control and for an amodal figure. This modulation is one of the earliest direct evidences for a low-level processing of illusory forms in the human brain. Meanwhile, larger N1s were obtained for the control figures than for the illusory figures in the notch mode of presentation. While this new type of N1 modulation could shed some light on the stage of processing indexed by this deflection, several propositions are put forward to account for the P1 and N1 variations found.

Face perception in high-functioning autistic adults: evidence for superior processing of face parts, not for a configural face-processing deficit.

Configural processing in autism was studied in Experiment 1 by using the face inversion effect. A normal inversion effect was observed in the participants with autism, suggesting intact configural face processing. A priming paradigm using partial or complete faces served in Experiment 2 to assess both local and configural face processing. Overall, normal priming effects were found in participants with autism, irrespective of whether the partial face primes were intuitive face parts (i.e., eyes, nose, etc.) or arbitrary segments. An exception, however, was that participants with autism showed magnified priming with single face parts relative to typically developing control participants. The present findings argue for intact configural processing in autism along with an enhanced processing for individual face parts. The face-processing peculiarities known to characterize autism are discussed on the basis of these results and past congruent results with nonsocial stimuli.

An ERP study of famous face incongruity detection in middle age.

Age-related changes in famous face incongruity detection were examined in middle-aged (mean = 50.6) and young (mean = 24.8) subjects. Behavioral and ERP responses were recorded while subjects, after a presentation of a "prime face" (a famous person with the eyes masked), had to decide whether the following "test face" was completed with its authentic eyes (congruent) or with other eyes (incongruent). The principal effects of advancing age were (1) behavioral difficulties in discriminating between incongruent and congruent faces; (2) a reduced N400 effect due to N400 enhancement for both congruent and incongruent faces; (3) a latency increase of both N400 and P600 components. ERPs to primes (face encoding) were not affected by aging. These results are interpreted in terms of early signs of aging.

Event-related potentials to structural familiar face incongruity processing.

Thirty scalp sites were used to investigate the specific topography of the event-related potentials (ERPs) related to face associative priming when masked eyes of familiar faces were completed with either the proper features or incongruent ones. The enhanced negativity of N210 and N350, due to structural incongruity of faces, have a "category specific" inferotemporal localization on the scalp. Additional analyses support the existence of multiple ERP features within the temporal interval typically associated with N400 (N350 and N380), involving occipitotemporal and centroparietal areas. Seven reliable dipole locations have been evidenced using the brain electrical source analysis algorithm. Some of these localizations (fusiform, parahippocampal) are already known to be involved in face recognition, the other ones being related to general cognitive processes related to the task's demand. Because of their specific topography, the observed effects suggest that the face structural congruency process might involve early specialized neocortical areas in parallel with cortical memory circuits in the integration of perceptual and cognitive face processing.

Differential processing of part-to-whole and part-to-part face priming: an ERP study.

We provide electrophysiological evidence supporting the hypothesis that part and whole face processing involve distinct functional mechanisms. We used a congruency judgment task and studied part-to-whole and part-to-part priming effects. Neither part-to-whole nor part-to-part conditions elicited early congruency effects on face-specific ERP components, suggesting that activation of the internal representations should occur later on. However, these components showed differential responsiveness to whole faces and isolated eyes. In addition, although late ERP components were affected when the eye targets were not associated with the prime in both conditions, their temporal and topographical features depended on the latter. These differential effects suggest the existence of distributed neural networks in the inferior temporal cortex where part and whole facial representations may be stored.

Face and shape repetition effects in humans: a spatio-temporal ERP study.

The neural bases of repetition effects for faces and non-significant shapes was studied using Mooneys' faces presented upright (face) or upside down (shape) with a repetition interval of 8 min 30 s-1. Scalp potentials and current density maps on 30 electrodes were compatible with an involvement of the infero-temporal and fusiform gyri (from 50 to at least 250 ms), mainly on the right, for both faces and shapes; the hippocampus and adjacent areas (around 300 ms), specifically for faces; the medial temporal lobes (450-650 ms) again independent of stimulus meaning. These results suggest that the facilitation of perception due to repetition involves both neocortical specialized areas and the medial temporal lobe, with different timings of activation. They further suggest that memory updating takes place more rapidly for faces than for meaningless shapes and that face recognition may be, at least partly, functionally encapsulated.