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1.
Pan Afr Med J ; 37: 11, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-33062114

RESUMEN

Primary pulmonary lymphoma is a rare entity. Furthermore, simultaneous bilateral spontaneous pneumothorax (SBSP) is a very rare condition which is often related to therapeutic complications. We present, to the best of our knowledge, the first case of primary pulmonary mucosa associated lymphoid tissue (MALT) lymphoma revealed by SBSP. A 50-year-old female was diagnosed with organizing pneumonia. One month later, she presented with sudden chest pain and shortness of breath due to SBSP. Bilateral chest tubes were inserted. A scan- guided right lung biopsy led to the diagnosis of primary pulmonary MALT lymphoma. The patient was treated with R-CHOP chemotherapy. The association between lymphoma and pneumothorax is extremely rare, often related to therapeutic toxicity. We report the case of SBSP as the first manifestation of primary pulmonary MALT lymphoma.


Asunto(s)
Neoplasias Pulmonares/diagnóstico , Linfoma de Células B de la Zona Marginal/diagnóstico , Neumotórax/etiología , Protocolos de Quimioterapia Combinada Antineoplásica/administración & dosificación , Dolor en el Pecho/etiología , Tubos Torácicos , Ciclofosfamida/administración & dosificación , Doxorrubicina/administración & dosificación , Disnea/etiología , Femenino , Humanos , Neoplasias Pulmonares/patología , Neoplasias Pulmonares/terapia , Linfoma de Células B de la Zona Marginal/patología , Linfoma de Células B de la Zona Marginal/terapia , Persona de Mediana Edad , Prednisona/administración & dosificación , Rituximab/administración & dosificación , Vincristina/administración & dosificación
2.
Respir Med Case Rep ; 31: 101238, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-33088707

RESUMEN

Mounier-Kuhn syndrome or tracheobronchomegaly is a rare disease characterized by marked dilation of the trachea and proximal bronchi with recurrent lower tract respiratory infections. Computed tomography and bronchoscopy are the key tools to accomplish the diagnosis. This is a condition with a clinical polymorphism, symptoms vary from minor with preserved respiratory function, to very severe with life threatening exacerbations leading to respiratory failure and premature death. The treatment is mainly symptomatic, stenting or surgery are reserved to extreme cases.Herein, we report two cases of the same condition with different clinical signs and diverse outcome.

3.
Respir Med Case Rep ; 29: 100992, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-31956477

RESUMEN

Clinical reports of symptomatic choroidal metastasis as the initial presentation of lung cancer are rare. Here, we report such a presentation in a female patient of non small cell lung cancer. She presented with loss of vision in her left eye. On further analyses, the patient was diagnosed with a lung adenocarcinoma.

5.
Tunis Med ; 82(8): 735-41, 2004 Aug.
Artículo en Francés | MEDLINE | ID: mdl-15532768

RESUMEN

The incidence of chronic obstructive pulmonary disease (COPD) is increasing particularly in developing countries. Their prognosis depend on several factors in particular the one second forced expiratory volume (FEV1) decline. To study FEV1 decline speed and factors affecting it, we carried out a retrospective study of 160 cases of COPD in stable state and heaving at least two FEV1 measures at 6 months of interval in the minimum and. The middle age was 63 +/- 12 yr, 52% was former smokers and 46% current smokers, with middle of 50 +/- 27 pack-yr. The FEV1 decline was calculated by linear regression models. The decline average in FEV1 with time was 72 +/- 55 ml/yr. Absolute value was higher than 30 ml/yr therefore more accelerated than general population in 79% of cases. We confirmed by multivariate analysis that age and smoking habit and increased the FEV1 decline. However this last correlated with FEV1% predicted. We concluded that the decline of FEV1 is higher in COPD that in the general population and slowing it needs smoking stop.


Asunto(s)
Enfermedad Pulmonar Obstructiva Crónica/fisiopatología , Ventilación Pulmonar , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Volumen Espiratorio Forzado , Humanos , Masculino , Persona de Mediana Edad , Análisis Multivariante , Estudios Retrospectivos
6.
Rev Med Suisse Romande ; 124(7): 427-9, 2004 Jul.
Artículo en Francés | MEDLINE | ID: mdl-15379167

RESUMEN

The sleep apnea syndrome (SAS) and hypothyroidism have several common signs. This similarity creates a significant risk of undiagnosed hypothyroidism during the SAS. We studied the interest of thyroid function testing at patients suspected of having SAS. 201 consecutive patients, having a suspicion of SAS without history of hypothyroidism, underwent polysomnography (PSG) and biochemical thyroid testing. 91 patients (47%) had a SAS. Three patients among them (1.5% of patients undergoing PSG or 3.3% of those having a SAS) had previously undiagnosed hypothyroidism. These three patients have been treated by thyroxine. After euthyroidism was obtained by the treatment, SAS disappeared in 2 patients. The prevalence of the hypothyroidism in patients suspected of having SAS is not different from the one in the general population. However it is greater in patients with SAS. So we can conclude that biochemical screening for hypothyroidism is indicated only in case of proven SAS, in order to distinguish between a primary and a secondary origin.


Asunto(s)
Hipotiroidismo/complicaciones , Hipotiroidismo/diagnóstico , Síndromes de la Apnea del Sueño/etiología , Pruebas de Función de la Tiroides , Adulto , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Prospectivos
7.
Tunis Med ; 82(2): 209-13, 2004 Feb.
Artículo en Francés | MEDLINE | ID: mdl-15185597

RESUMEN

Obstructive sleep apnoea (OSA) is a relatively common disorder, in developed country with prevalence estimated to lie between 2 and 4% in adult population. The diagnosis of this syndrome is made on the basis of characteristic clinical features and the results of nocturnal polysomnography. There is no data concerning the OSA in developing country. It is therefore of interest to determine the clinic and polysomnographic profile of this disease and to landmark factors correlated with severity in our country. This was achieved by studying a set of 63 OSA. The mean of age was 53 + 13 years with sex ratio 1. The means of Epworth sleepiness scale score, BMI and Apnoea/Hypopnoea index (AHI) were respectively 16 + 4, 38.8 + 7 kg/m2 and 51.7 + 28.6. 44% of patients have OSA severe with IAH > 50/h. Arousal index and desaturation index were respectively 36.4 + 21.7 and 49 + 26. Trial of continuous positive airway pressure (CPAP) therapy was proposed first to 40 patients, 17 were able to use CPAP.


Asunto(s)
Países en Desarrollo , Apnea Obstructiva del Sueño/patología , Adulto , Edad de Inicio , Femenino , Humanos , Masculino , Persona de Mediana Edad , Respiración con Presión Positiva , Estudios Retrospectivos , Índice de Severidad de la Enfermedad , Apnea Obstructiva del Sueño/terapia , Túnez
8.
Tunis Med ; 81(10): 828-31, 2003 Oct.
Artículo en Francés | MEDLINE | ID: mdl-17722802

RESUMEN

We report a case of pulmonary infarction in a 72-year-old woman who was hospitalised for hemoptysis, chest pain and weight and coin a lesion in the loss periphery of the left lower lobe. Camputed tomography of the chest demonstrated a sub pleural solitary nodule with spicular radiation. Video-assisted thoracoscopic surgery was performed to obtain a histological diagnosis. Thoracoscopic examination showed a lesion that evoked chronic abscess. Histological examination confirmed an ischemic infarction. This is the second case of pseudotumor due to pulmonary infarction that was diagnosed by video-assisted thoracoscopic resection.


Asunto(s)
Embolia Pulmonar/complicaciones , Nódulo Pulmonar Solitario/diagnóstico , Cirugía Torácica Asistida por Video , Anciano , Femenino , Humanos
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