1.
Am J Transplant
; 23(10): 1622-1625, 2023 10.
Artículo
en Inglés
| MEDLINE
| ID: mdl-37187295
RESUMEN
We report the case of a 12-year-old boy with primary hyperoxaluria type 2 (PH2) presenting with end-stage renal disease and systemic oxalosis who underwent a combined living donor liver and kidney transplant from 3 donors, 1 of whom was a heterozygous carrier of the mutation. Plasma oxalate and creatinine levels normalized immediately following the transplant and remain normal after 18 months. We recommend combined liver and kidney transplantation as the preferred therapeutic option for children with primary hyperoxaluria type 2 with early-onset end-stage renal disease.
Asunto(s)
Hiperoxaluria Primaria , Hiperoxaluria , Fallo Renal Crónico , Trasplante de Riñón , Trasplante de Hígado , Masculino , Niño , Humanos , Donadores Vivos , Hiperoxaluria Primaria/genética , Hiperoxaluria Primaria/cirugía , Fallo Renal Crónico/cirugía , Hígado
2.