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Nanotechnology ; 33(4)2021 Nov 05.
Artículo en Inglés | MEDLINE | ID: mdl-34598165

RESUMEN

Phenolic compounds (like 4-nitrophenol) and dyes (like methyl orange) are common by-products discharged by many industries as wastes; they are toxic and may induce discomfort and irritation in humans when ingested. Most of these compounds can be made less toxic through catalytic degradation. Metal oxide nanoparticles are found to have high catalytic activity and can degrade toxic phenolic compounds and dyes. In the current study, pomegranate rind extract was used for the green synthesis of iron oxide nanoparticles that exhibited an octahedron morphology revealed by scanning electron microscopy analysis. Energy dispersive x-ray analysis showed 47.96% content of Fe (by weight); high resolution-transmission electron microscopy analysis confirmed that the nanoparticles had a particle size of 22.54 ± 4.13 nm. The particles were further characterized by x-ray diffraction, fourier transform-infrared spectroscopy, vibrating sample magnetometer, and thermogravimetric analysis. The nanoparticle proved to be efficient in reducing 4-nitrophenol and methyl orange. It was also found to be non-toxic towards murine macrophages, RAW 264.7 with good ROS-scavenging potential compared to control.


Asunto(s)
Depuradores de Radicales Libres , Tecnología Química Verde/métodos , Nanopartículas de Magnetita , Extractos Vegetales , Granada (Fruta)/química , Animales , Supervivencia Celular/efectos de los fármacos , Colorantes , Depuradores de Radicales Libres/química , Depuradores de Radicales Libres/farmacología , Depuradores de Radicales Libres/toxicidad , Nanopartículas de Magnetita/química , Nanopartículas de Magnetita/toxicidad , Ratones , Nitrofenoles/análisis , Nitrofenoles/metabolismo , Extractos Vegetales/química , Extractos Vegetales/farmacología , Extractos Vegetales/toxicidad , Células RAW 264.7 , Especies Reactivas de Oxígeno/análisis , Especies Reactivas de Oxígeno/metabolismo
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