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1.
J Gen Intern Med ; 16(11): 755-62, 2001 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-11722690

RESUMEN

OBJECTIVE: To measure and compare patient satisfaction with care in resident and attending physician internal medicine ambulatory care clinics. DESIGN: A cross-sectional survey using a questionnaire derived from the Visit-Specific Satisfaction Questionnaire (VSQ) and Patient Satisfaction Index (PSI) distributed from March 1998 to May 1998. SETTING: Four clinics based at a university teaching hospital and the associated Veterans' Affairs (VA) hospital. PARTICIPANTS: Two hundred eighty-eight patients of 76 resident and 25 attending physicians. RESULTS: Patients of resident physicians at the university site were more likely to be African American, male, have lower socioeconomic status and have lower physical and mental health scores on the Short Form-12 than patients of university attendings. Patients of resident and attending physicians at the VA site were similar. In multivariate analyses, patients of university attending physicians were more likely to be highly satisfied than patients of university residents on the VSQ-Physician (odds ratio [OR], 3.5; 95% confidence interval [CI], 1.6 to 7.8) and the PSI-Physician (OR, 10.1; 95% CI, 3.7 to 27.4) summary scores. Differences were not seen on the summary scores at the VA site. Two individual items displayed significant differences between residents and attendings at both sites: "personal manner (courtesy, respect, sensitivity, friendliness) of the doctor" (P

Asunto(s)
Internado y Residencia , Cuerpo Médico de Hospitales , Servicio Ambulatorio en Hospital , Satisfacción del Paciente , Estudios Transversales , Femenino , Accesibilidad a los Servicios de Salud , Estado de Salud , Hospitales de Enseñanza , Hospitales de Veteranos , Humanos , Masculino , Persona de Mediana Edad , Relaciones Médico-Paciente , Clase Social , Encuestas y Cuestionarios
4.
J Gen Intern Med ; 16(9): 590-8, 2001 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-11556939

RESUMEN

OBJECTIVE: To identify the factors associated with the use of arterial blood gas (ABG) and pulse oximetry (PO) in the initial management of patients with community-acquired pneumonia (CAP) and arterial hypoxemia at presentation. PARTICIPANTS: A total of 944 outpatients and 1,332 inpatients with clinical and radiographic evidence of CAP prospectively enrolled from 5 study sites in the United States and Canada. ANALYSES: Separate multivariate logistic regression analyses were used to 1) compare measurement of ABG and PO within 48 hours of presentation across sites while controlling for patient differences, and 2) identify factors associated with arterial hypoxemia (PaO2 <60 mm Hg or SaO2 <90% for non-African Americans and <92% for African Americans) while breathing room air. RESULTS: Range of ABG use by site was from 0% to 6.4% (P =.06) for outpatients and from 49.2% to 77.3% for inpatients (P <.001), while PO use ranged from 9.4% to 57.8% for outpatients (P <.001) and from 47.9% to 85.1% for inpatients (P <.001). Differences among sites remained after controlling for patient demographic characteristics, comorbidity, and illness severity. In patients with 1 or more measurements of oxygenation at presentation, hypoxemia was independently associated with 6 risk factors: age >30 years (odds ratio [OR], 3.2; 95% confidence interval [CI], 1.7 to 5.9), chronic obstructive pulmonary disease (OR, 1.9; 95% CI, 1.4 to 2.6), congestive heart failure (OR, 1.5; 95% CI, 1.0 to 2.1), respiratory rate >24 per minute (OR, 2.3; 95% CI, 1.8 to 3.0), altered mental status (OR, 1.6; 95% CI, 1.1 to 2.3), and chest radiographic infiltrate involving >1 lobe (OR, 2.2; 95% CI, 1.7 to 2.9). The prevalence of hypoxemia among those tested ranged from 13% for inpatients with no risk factors to 54.6% for inpatients with > or =3 risk factors. Of the 210 outpatients who had > or =2 of these risk factors, only 64 (30.5%) had either an ABG or PO performed. In the 48 outpatients tested without supplemental O2 with > or =2 risk factors 8.3% were hypoxemic. CONCLUSIONS: In the initial management of CAP, use of ABG and PO varied widely across sites. Increasing the assessment of arterial oxygenation among patients with CAP is likely to increase the detection of arterial hypoxemia, particularly among outpatients.


Asunto(s)
Hipoxia/sangre , Neumonía/sangre , Adulto , Anciano , Análisis de los Gases de la Sangre/efectos adversos , Infecciones Comunitarias Adquiridas/sangre , Infecciones Comunitarias Adquiridas/diagnóstico por imagen , Humanos , Hipoxia/terapia , Modelos Lineales , Masculino , Persona de Mediana Edad , Oximetría/efectos adversos , Neumonía/diagnóstico por imagen , Neumonía/microbiología , Estudios Prospectivos , Radiografía , Factores de Riesgo
6.
Med Clin North Am ; 85(2): 423-56, xi, 2001 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-11233954

RESUMEN

This article focuses on the evaluation of patients with syncope, a symptom not a disease. Syncope is a transient loss of consciousness associated with loss of postural tone with spontaneous recovery. The authors discuss the utility of an indications for different diagnostic tests, the indications for hospital admission, and the management of patients with certain known causes of syncope, including vasovagal and arrhythmic.


Asunto(s)
Síncope/diagnóstico , Síncope/terapia , Algoritmos , Antiarrítmicos/uso terapéutico , Estimulación Cardíaca Artificial , Diagnóstico Diferencial , Técnicas de Diagnóstico Cardiovascular , Electroencefalografía , Hospitalización , Humanos , Pronóstico , Pruebas Psicológicas , Factores de Riesgo , Prevención Secundaria , Síncope/etiología , Tomografía Computarizada por Rayos X
7.
Arch Intern Med ; 161(2): 189-97, 2001 Jan 22.
Artículo en Inglés | MEDLINE | ID: mdl-11176732

RESUMEN

BACKGROUND: Inadequate treatments are reported for depressed patients cared for by primary care physicians (PCPs). Providing feedback and evidence-based treatment recommendations for depression to PCPs via electronic medical record improves the quality of interventions. METHODS: Patients presenting to an urban academically affiliated primary care practice were screened for major depression with the Primary Care Evaluation of Mental Disorders (PRIME-MD). During 20-month period, 212 patients met protocol-eligibility criteria and completed a baseline interview. They were cared for by 16 board-certified internists, who were electronically informed of their patients' diagnoses, and randomized to 1 of 3 methods of exposure to guideline-based advice for treating depression (active, passive, and usual care). Ensuing treatment patterns were assessed by medical chart review and by patient self-report at baseline and 3 months. RESULTS: Median time for PCP response to the electronic message regarding the patient's depression diagnosis was 1 day (range, 1-95 days). Three days after notification, 120 (65%) of 186 PCP responses indicated agreement with the diagnosis, 24 (13%) indicated disagreement, and 42 (23%) indicated uncertainty. Primary care physicians who agreed with the diagnoses sooner were more likely to make a medical chart notation of depression, begin antidepressant medication therapy, or refer to a mental health specialist (P<.001). There were no differences in the agreement rate or treatments provided across guideline exposure conditions. CONCLUSIONS: Electronic feedback of the diagnosis of major depression can affect PCP initial management of the disorder. Further study is necessary to determine whether this strategy, combined with delivery of treatment recommendations, can improve clinical outcomes in routine practice.


Asunto(s)
Trastorno Depresivo/diagnóstico , Trastorno Depresivo/terapia , Sistemas de Registros Médicos Computarizados , Médicos de Familia , Adolescente , Adulto , Medicina Basada en la Evidencia , Femenino , Adhesión a Directriz , Humanos , Medicina Interna , Masculino , Persona de Mediana Edad , Guías de Práctica Clínica como Asunto , Encuestas y Cuestionarios
9.
Am J Med ; 109(5): 378-85, 2000 Oct 01.
Artículo en Inglés | MEDLINE | ID: mdl-11020394

RESUMEN

PURPOSE: Patients with pneumonia often remain hospitalized after becoming clinically stable, without demonstrated benefits on outcome. The purposes of this study were to assess the relation between length of hospital stay and daily medical care costs and to estimate the potential cost savings associated with a reduced length of stay for patients with pneumonia. SUBJECTS AND METHODS: As part of a prospective study of adults hospitalized with community-acquired pneumonia at a community hospital and two university teaching hospitals, daily medical care costs were estimated by multiplying individual charges by department-specific cost-to-charge ratios obtained from each hospital's Medicare cost reports. RESULTS: The median total cost of hospitalization for all 982 inpatients was $5, 942, with a median daily cost of $836, including $491 (59%) for room and $345 (41%) for non-room costs. Average daily non-room costs were 282% greater on the first hospital day, 59% greater on the second day, and 19% greater on the third day than the average daily cost throughout the hospitalization (all P <0.05), and were 14% to 72% lower on the last 3 days of hospitalization. Average daily room costs remained relatively constant throughout the hospital stay, with the exception of the day of discharge. A projected mean savings of $680 was associated with a 1-day reduction in length of stay. CONCLUSIONS: Despite institutional differences in total costs, patterns of daily resource use throughout hospitalization were similar at all institutions. A 1-day reduction in length of stay might yield substantial cost-savings.


Asunto(s)
Costos de Hospital/estadística & datos numéricos , Tiempo de Internación/economía , Neumonía/economía , Adulto , Anciano , Boston , Estudios de Cohortes , Infecciones Comunitarias Adquiridas/economía , Ahorro de Costo/estadística & datos numéricos , Femenino , Humanos , Tiempo de Internación/estadística & datos numéricos , Masculino , Persona de Mediana Edad , Análisis Multivariante , Nueva Escocia , Pennsylvania , Evaluación de Procesos, Atención de Salud , Índice de Severidad de la Enfermedad
10.
J Gen Intern Med ; 15(9): 638-46, 2000 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-11029678

RESUMEN

OBJECTIVE: To describe the presentation, resolution of symptoms, processes of care, and outcomes of pneumococcal pneumonia, and to compare features of the bacteremic and nonbacteremic forms of this illness. DESIGN: A prospective cohort study. SETTING: Five medical institutions in 3 geographic locations. PARTICIPANTS: Inpatients and outpatients with community-acquired pneumonia (CAP). MEASUREMENTS: Sociodemographic characteristics, respiratory and nonrespiratory symptoms, and physical examination findings were obtained from interviews or chart review. Severity of illness was assessed using a validated prediction rule for short-term mortality in CAP. Pneumococcal pneumonia was categorized as bacteremic; nonbacteremic, pure etiology; or nonbacteremic, mixed etiology. MAIN RESULTS: One hundred fifty-eight (6.9%) of 2,287 patients (944 outpatients, 1,343 inpatients) with CAP had pneumococcal pneumonia. Sixty-five (41%) of the 158 with pneumococcal pneumonia were bacteremic; 74 (47%) were nonbacteremic with S. pneumoniae as sole pathogen; and 19 (12%) were nonbacteremic with S. pneumoniae as one of multiple pathogens. The pneumococcal bacteremia rate for outpatients was 2.6% and for inpatients it was 6.6%. Cough, dyspnea, and pleuritic pain were common respiratory symptoms. Hemoptysis occurred in 16% to 22% of the patients. A large number of nonrespiratory symptoms were noted. Bacteremic patients were less likely than nonbacteremic patients to have sputum production and myalgias (60% vs 82% and 33% vs 57%, respectively; P <.01 for both), more likely to have elevated blood urea nitrogen and serum creatinine levels, and more likely to receive penicillin therapy. Half of bacteremic patients were in the low risk category for short-term mortality (groups I to III), similar to the nonbacteremic patients. None of the 32 bacteremic patients in risk groups I to III died, while 7 of 23 (30%) in risk group V died. Intensive care unit admissions and pneumonia-related mortality were similar between bacteremic and nonbacteremic groups, although 46% of the bacteremic group had respiratory failure compared with 32% and 37% for the other groups. The nonbacteremic pure etiology patients returned to household activities faster than bacteremic patients. Symptoms frequently persisted at 30 days: cough (50%); dyspnea (53%); sputum production (48%); pleuritic pain (13%); and fatigue (63%). CONCLUSIONS: There were few differences in the presentation of bacteremic and nonbacteremic pneumococcal pneumonia. About half of bacteremic pneumococcal pneumonia patients were at low risk for mortality. Symptom resolution frequently was slow.


Asunto(s)
Neumonía Neumocócica , Anciano , Antibacterianos/uso terapéutico , Bacteriemia/microbiología , Estudios de Cohortes , Diagnóstico Diferencial , Femenino , Humanos , Masculino , Persona de Mediana Edad , Neumonía Neumocócica/diagnóstico , Neumonía Neumocócica/tratamiento farmacológico , Neumonía Neumocócica/microbiología , Neumonía Neumocócica/mortalidad , Estudios Prospectivos , Medición de Riesgo , Índice de Severidad de la Enfermedad , Streptococcus pneumoniae/aislamiento & purificación , Análisis de Supervivencia , Resultado del Tratamiento
11.
Am J Health Syst Pharm ; 57(16): 1506-10, 2000 Aug 15.
Artículo en Inglés | MEDLINE | ID: mdl-10965396

RESUMEN

The Notes section welcomes the following types of contributions: (1) practical innovations or solutions to everyday practice problems, (2) substantial updates or elaborations on work previously published by the same authors, (3) important confirmations of research findings previously published by others, and (4) short research reports, including practice surveys, of modest scope or interest. Notes should be submitted with AJHP's manuscript checklist. The text should be concise, and the number of references, tables, and figures should be limited.


Asunto(s)
Antiinfecciosos/uso terapéutico , Cefuroxima/uso terapéutico , Cefalosporinas/uso terapéutico , Neumonía/tratamiento farmacológico , Anciano , Estudios de Casos y Controles , Infecciones Comunitarias Adquiridas/clasificación , Infecciones Comunitarias Adquiridas/tratamiento farmacológico , Prescripciones de Medicamentos , Servicio de Urgencia en Hospital , Femenino , Hospitalización , Humanos , Masculino , Rol del Médico , Neumonía/clasificación , Índice de Severidad de la Enfermedad
12.
Am J Med ; 107(1): 5-12, 1999 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-10403346

RESUMEN

PURPOSE: To assess the variation in length of stay for patients hospitalized with community-acquired pneumonia and to determine whether patients who are treated in hospitals with shorter mean stays have worse medical outcomes. SUBJECTS AND METHODS: We prospectively studied a cohort of 1,188 adult patients with community-acquired pneumonia who had been admitted to one community and three university teaching hospitals. We compared patients' mean length of stay, mortality, hospital readmission, return to usual activities, return to work, and pneumonia-related symptoms among the four study hospitals. All outcomes were adjusted for baseline differences in severity of illness and comorbidity. RESULTS: Adjusted interhospital differences in mean length of stay ranged from 0.9 to 2.3 days (P <0.001). When the risk of each medical outcome was compared between patients admitted to the hospital with the shortest length of stay and those admitted to longer stay hospitals, there were no differences in mortality [relative risk (RR) = 0.7; 95% CI, 0.3 to 1.7], hospital readmission (RR = 0.8; 95% CI, 0.5 to 1.2), return to usual activities (RR = 1.1; 95% CI, 0.9 to 1.3), or return to work (RR = 1.2; 95% CI, 0.8 to 2.0) during the first 14 days after discharge, or in the mean number of pneumonia-related symptoms 30 days after admission (P = 0.54). CONCLUSIONS: We observed substantial interhospital variation in the lengths of stay for patients hospitalized with community-acquired pneumonia. The finding that medical outcomes were similar in patients admitted to the hospital with the shortest length of stay and those admitted to hospitals with longer mean lengths of stay suggests that hospitals with longer stays may be able to reduce the mean duration of hospitalization for this disease without adversely affecting patient outcomes.


Asunto(s)
Infecciones Comunitarias Adquiridas/terapia , Tiempo de Internación/estadística & datos numéricos , Evaluación de Resultado en la Atención de Salud/estadística & datos numéricos , Neumonía/terapia , Adulto , Anciano , Anciano de 80 o más Años , Boston , Infecciones Comunitarias Adquiridas/complicaciones , Comorbilidad , Femenino , Humanos , Masculino , Persona de Mediana Edad , Nueva Escocia , Pennsylvania , Neumonía/complicaciones , Estudios Prospectivos , Riesgo , Factores de Riesgo
13.
Arch Intern Med ; 159(9): 970-80, 1999 May 10.
Artículo en Inglés | MEDLINE | ID: mdl-10326939

RESUMEN

BACKGROUND: Although understanding the processes of care and medical outcomes for patients with community-acquired pneumonia is instrumental to improving the quality and cost-effectiveness of care for this illness, limited information is available on how physicians manage patients with this illness or on medical outcomes other than short-term mortality. OBJECTIVES: To describe the processes of care and to assess a broad range of medical outcomes for ambulatory and hospitalized patients with community-acquired pneumonia. METHODS: This prospective, observational study was conducted at 4 hospitals and 1 health maintenance organization in Pittsburgh, Pa, Boston, Mass, and Halifax, Nova Scotia. Data were collected via patient interviews and reviews of medical records for 944 outpatients and 1343 inpatients with clinical and radiographic evidence of community-acquired pneumonia. Processes of care and medical outcomes were assessed 30 days after presentation. RESULTS: Only 29.7% of outpatients had 1 or more microbiologic tests performed, and only 5.7% had an assigned microbiologic cause. Although 95.7% of inpatients had 1 or more microbiologic tests performed, a cause was established in only 29.6%. Six outpatients (0.6%) died, and 3 of these deaths were pneumonia related. Of surviving outpatients, 8.0% had 1 or more medical complications. At 30 days, 88.9% (nonemployed) to 95.6% (employed) of the surviving outpatients had returned to usual activities, yet 76.0% of outpatients had 1 or more persisting pneumonia-related symptoms. Overall, 107 inpatients (8.0%) died, and 81 of these deaths were pneumonia related. Most surviving inpatients (69.0%) had 1 or more medical complications. At 30 days, 57.3% (non-employed) to 82.0% (employed) of surviving inpatients had returned to usual activities, and 86.1% had 1 or more persisting pneumonia-related symptoms. CONCLUSIONS: In this study, conducted primarily at hospital sites with affiliated medical education training programs, virtually all outpatients and most inpatients had pneumonia of unknown cause. Although outpatients had an excellent prognosis, pneumonia-related symptoms often persisted at 30 days. Inpatients had substantial mortality, morbidity, and pneumonia-related symptoms at 30 days.


Asunto(s)
Infecciones Comunitarias Adquiridas/terapia , Neumonía/terapia , Adulto , Anciano , Infecciones Comunitarias Adquiridas/diagnóstico , Infecciones Comunitarias Adquiridas/microbiología , Infecciones Comunitarias Adquiridas/mortalidad , Femenino , Humanos , Masculino , Persona de Mediana Edad , Evaluación de Procesos y Resultados en Atención de Salud , Neumonía/diagnóstico , Neumonía/microbiología , Neumonía/mortalidad , Prevalencia , Estudios Prospectivos , Resultado del Tratamiento
14.
Arch Intern Med ; 159(4): 375-80, 1999 Feb 22.
Artículo en Inglés | MEDLINE | ID: mdl-10030311

RESUMEN

BACKGROUND: Patients with syncope frequently present with multitude of other symptoms but their significance in predicting morbidity or mortality has not been previously studied. OBJECTIVE: To determine if certain symptoms can be used to identify syncope patients at risk for cardiac arrhythmias, mortality, or recurrence of syncope. PATIENTS AND METHODS: From August 1987 to February 1991, we prospectively evaluated patients with syncope from outpatient, inpatient, and emergency department services of a university medical center. These patients were interviewed, charts were reviewed, and detailed information on 19 symptoms and comorbidities was obtained. A cause of syncope was assigned using standardized diagnostic criteria. All patients were followed up at 3-month intervals for at least 1 year for recurrence of syncope and mortality. Patients in whom the cause of syncope was determined by medical history and physical examination alone were not included in our analysis. RESULTS: History and physical examination led to the cause of syncope in 222 of 497 patients enrolled. In the remaining 275 patients, the absence of nausea and vomiting before syncope (odds ratio, 7.1) and electrocardiographic abnormalities (odds ratio, 23.5) were predictors of arrhythmic syncope. Underlying cardiac disease was the only predictor of 1-year mortality. No symptom remained as independent predictor for 1-year mortality or syncope recurrence. CONCLUSIONS: Symptoms, although important in assigning many noncardiac causes, are not useful in risk-stratifying patients whose cause of syncope cannot be identified by other history and physical examination. Triage decisions and management plans should be based on pre-existing cardiac disease or electrocardiographic abnormalities, which are important predictors of arrhythmic syncope and mortality.


Asunto(s)
Arritmias Cardíacas/etiología , Arritmias Cardíacas/mortalidad , Síncope/complicaciones , Síncope/mortalidad , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Diagnóstico Diferencial , Femenino , Humanos , Masculino , Persona de Mediana Edad , Análisis Multivariante , Valor Predictivo de las Pruebas , Recurrencia , Riesgo
15.
Am J Med Sci ; 317(2): 110-6, 1999 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-10037114

RESUMEN

Upright tilt testing is commonly used in the evaluation of patients with syncope to provoke hypotension and/or bradycardia in the laboratory. The most common type of response is provocation of neurally mediated syndrome (vasovagal syncope). The American College of Cardiology Expert Consensus has proposed indications for tilt testing. The most common indication is recurrent syncope of unexplained cause. Upright tilt testing methods have not been standardized. The most common protocols in this country use a tilt angle of 60-80 degrees and use isoproterenol infusion after a period of drug-free tilt testing. The sensitivity of upright tilt testing is estimated to be 67-83%, and the specificity is between 75 and 100%. The reproducibility of the test has been variable. In patients with unexplained syncope, positive responses are found to be 50% without the use of isoproterenol and 64% with the use of isoproterenol. Many different treatments have been used. At this time, there is no consensus regarding the most effective treatment. Beta-blockers and fludrocortisone plus salt are the most commonly used drugs. Pacemakers have been used, but their role is ill-defined at this time.


Asunto(s)
Sistema Nervioso Autónomo/fisiopatología , Síncope/etiología , Síncope/fisiopatología , Pruebas de Mesa Inclinada , Agonistas Adrenérgicos beta , Diagnóstico Diferencial , Humanos , Isoproterenol , Sensibilidad y Especificidad , Síncope/diagnóstico , Pruebas de Mesa Inclinada/métodos
16.
Int J Psychiatry Med ; 29(3): 267-86, 1999.
Artículo en Inglés | MEDLINE | ID: mdl-10642902

RESUMEN

OBJECTIVE: Using the Agency for Health Care Policy and Research Depression Guideline Panel's recommendations as its focus, this article describes a step-by-step approach for disseminating a paper-based depression guideline to primary care physicians via a commercially available electronic medical record (EMR) system. METHOD: Description of the author's approach to disseminate an evidence-based depression treatment guideline to a group of primary care physicians using a commercially available EMR system and to evaluate the results. RESULTS: We review clinical considerations and practical barriers faced in this process with the expectation that our experiences can guide others attempting to disseminate psychiatric treatment guideline via EMR systems. CONCLUSIONS: The EMR offers critical efficiencies in disseminating state-of-the-art clinical practice guidelines and in directing the primary care physicians' use of them. Still, well-designed, randomized controlled trials are necessary to demonstrate their effectiveness at enhancing patient outcomes for major depression in primary care settings.


Asunto(s)
Centros Médicos Académicos/organización & administración , Redes de Comunicación de Computadores/estadística & datos numéricos , Depresión , Sistemas de Registros Médicos Computarizados , Guías de Práctica Clínica como Asunto , Atención Primaria de Salud/normas , Depresión/diagnóstico , Depresión/terapia , Humanos , Pennsylvania , Estados Unidos , United States Agency for Healthcare Research and Quality
17.
Can J Infect Dis ; 10(1): 39-46, 1999 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-22346371

RESUMEN

OBJECTIVE: To describe the use of sputum Gram stain and culture in patients with community-acquired pneumonia (CAP) and to determine the factors that are associated with obtaining sputum for culture. TYPE OF STUDY: Prospective observational cohort study of patients hospitalized for treatment of CAP at four medical institutions in three geographic locations. MAIN MEASUREMENTS: Results of Gram stain and culture of sputum; comparison of patients who had sputum processed for culture within 24 h of admission with those who did not have such a specimen processed during the first week of hospitalization; and the results of investigator assignment of etiology of pneumonia according to predefined criteria. RESULTS: Four hundred and seventy-eight of 1339 (36%) patients had a sputum specimen processed for culture within 24 h of admission. Patients who had a sputum specimen processed within 24 h of admission were more likely to be hospitalized at the Boston site (odds ratio [OR] 20.6) or Pittsburgh sites (3.4) and to have current sputum production, chronic obstructive lung disease and moderate or large amount of sputum. Female sex (0.4), neutropenia (0.05), and do not resuscitate status (0.36) were important predictors of failure to have a sputum processed for culture. The rate of Streptococcus pneumoniae isolation was highest in Boston, 53 of 269 (19.3 %) patients (P<0.001) compared with the other sites; Moraxella catarrhalis was isolated only at the Boston site. Sputum culture results served as the basis for the assignment of an etiological diagnosis of the pneumonia by investigators in 67% of 397 patients. CONCLUSIONS: Sputum is not processed for culture in the majority of patients with CAP. The factors that determine whether sputum is processed for culture within 24 h of admission are site of care and a variety of patient factors. Common respiratory pathogens when present in sputum culture tend to be used to assign an etiological diagnosis. A positive sputum culture result appears not to result in a more favourable outcome.

18.
Med Care ; 36(7): 977-87, 1998 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-9674616

RESUMEN

OBJECTIVES: The authors describe the relation of provider characteristics to processes, costs, and outcomes of medical care for elderly patients hospitalized for community-acquired pneumonia. METHODS: Using Medicare claims data, Medicare beneficiaries discharged from Pennsylvania hospitals during 1990 with community-acquired pneumonia were identified. Claims data were used to ascertain mortality, readmissions, use of procedures and physician consultations, and the costs of care. The relationship of these measures to provider characteristics was analyzed using regression techniques to adjust for patient characteristics, including comorbidity and microbial etiology. RESULTS: Among 22,294 pneumonia episodes studied, 30-day mortality was 17.0%. After adjusting for patient characteristics, 30-day mortality and readmission rates were unrelated to hospital teaching status or urban location or to physician specialty. Use of procedures and physician consultations was more common and costs were 11% higher among patients discharged from teaching hospitals compared with nonteaching hospitals. Similarly, costs were 15% higher at urban hospitals compared with rural hospitals. General internists and medical subspecialists used more procedures and had higher costs than family practitioners. CONCLUSIONS: Processes and costs of care for community-acquired pneumonia varied by provider characteristics, but neither mortality nor readmission rates did. These differences cannot be explained by clinical variables in the database. Further studies should determine whether less costly patterns of care for pneumonia, and perhaps other conditions, could replace more costly ones without compromising patient outcomes.


Asunto(s)
Infecciones Comunitarias Adquiridas/economía , Precios de Hospital/estadística & datos numéricos , Costos de Hospital/estadística & datos numéricos , Hospitales/clasificación , Medicina/clasificación , Evaluación de Procesos y Resultados en Atención de Salud , Neumonía/economía , Especialización , Anciano , Anciano de 80 o más Años , Análisis de Varianza , Femenino , Investigación sobre Servicios de Salud , Mortalidad Hospitalaria , Hospitales/estadística & datos numéricos , Humanos , Formulario de Reclamación de Seguro/economía , Masculino , Medicare/economía , Medicina/estadística & datos numéricos , Readmisión del Paciente/estadística & datos numéricos , Pennsylvania , Estados Unidos
19.
JAMA ; 279(18): 1452-7, 1998 May 13.
Artículo en Inglés | MEDLINE | ID: mdl-9600479

RESUMEN

CONTEXT: Many groups have developed guidelines to shorten hospital length of stay in pneumonia in order to decrease costs, but the length of time until a patient hospitalized with pneumonia becomes clinically stable has not been established. OBJECTIVE: To describe the time to resolution of abnormalities in vital signs, ability to eat, and mental status in patients with community-acquired pneumonia and assess clinical outcomes after achieving stability. DESIGN: Prospective, multicenter, observational cohort study. SETTING: Three university and 1 community teaching hospital in Boston, Mass, Pittsburgh, Pa, and Halifax, Nova Scotia. PATIENTS: Six hundred eighty-six adults hospitalized with community-acquired pneumonia. MAIN OUTCOME MEASURES: Time to resolution of vital signs, ability to eat, mental status, hospital length of stay, and admission to an intensive care, coronary care, or telemetry unit. RESULTS: The median time to stability was 2 days for heart rate (< or =100 beats/min) and systolic blood pressure (> or =90 mm Hg), and 3 days for respiratory rate (< or =24 breaths/min), oxygen saturation (> or =90%), and temperature (< or =37.2 degrees C [99 degrees F]). The median time to overall clinical stability was 3 days for the most lenient definition of stability and 7 days for the most conservative definition. Patients with more severe cases of pneumonia at presentation took longer to reach stability. Once stability was achieved, clinical deterioration requiring intensive care, coronary care, or telemetry monitoring occurred in 1% of cases or fewer. Between 65% to 86% of patients stayed in the hospital more than 1 day after reaching stability, and fewer than 29% to 46% were converted to oral antibiotics within 1 day of stability, depending on the definition of stability. CONCLUSIONS: Our estimates of time to stability in pneumonia and explicit criteria for defining stability can provide an evidence-based estimate of optimal length of stay, and outline a clinically sensible approach to improving the efficiency of inpatient management.


Asunto(s)
Tiempo de Internación/estadística & datos numéricos , Evaluación de Resultado en la Atención de Salud , Neumonía/terapia , Adulto , Boston , Estudios de Cohortes , Infecciones Comunitarias Adquiridas/terapia , Femenino , Hospitales de Enseñanza/estadística & datos numéricos , Hospitales Universitarios/estadística & datos numéricos , Humanos , Masculino , Persona de Mediana Edad , Nueva Escocia , Pennsylvania , Neumonía/fisiopatología , Guías de Práctica Clínica como Asunto , Estudios Prospectivos , Índice de Severidad de la Enfermedad , Factores de Tiempo
20.
Am J Med ; 104(1): 17-27, 1998 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-9528715

RESUMEN

PURPOSE: To assess the patterns of antimicrobial use, costs of antimicrobial therapy, and medical outcomes by institution in patients with community-acquired pneumonia. PATIENTS AND METHODS: The route, dose, and frequency of administration of all antimicrobial agents prescribed within 30 days of presentation were recorded for 927 outpatients and 1328 inpatients enrolled in the Pneumonia Patient Outcomes Research Team (PORT) multicenter, prospective cohort study. Total antimicrobial costs were estimated by summing drug costs, using average wholesale price for oral agents and institutional acquisition prices for parenteral agents, plus the costs associated with preparation and administration of parenteral therapy. Thirty-day outcome measures were mortality, subsequent hospitalization for outpatients, and hospital readmission for inpatients. RESULTS: Significant variation (P <0.05) in prescribing practices occurred for 17 of the 23 antimicrobial agents used in outpatients across 5 treatment sites, and for 18 of the 20 parenteral agents used in inpatients across 4 treatment sites. The median duration of antimicrobial therapy for treatment site ranged from 11 to 13 days for outpatients (P=0.01), and from 13 to 15 days for inpatients (P=0.49). The overall median cost of antimicrobial therapy was $12.90 for outpatients, and ranged from $10.80 to $58.90 among treatment sites (P <0.0001). The overall median cost of antimicrobial therapy was $228.70 for inpatients, and ranged from $183.70 to $315.60 among sites (P <0.0001). Mortality and hospital readmission for inpatients were not significantly different across sites after adjusting for baseline differences in patient demographic characteristics, comorbidity, and illness severity. Although subsequent hospitalization for outpatients differed by site, the rate was lowest for the site with the lowest antimicrobial costs. CONCLUSION: Variations in antimicrobial prescribing practices by treatment site exist for outpatients and inpatients with community-acquired pneumonia. Although variation in antimicrobial prescribing practices across institutions results in significant differences in antimicrobial costs, patients treated at institutions with the lowest antimicrobial costs do not demonstrate worse medical outcomes.


Asunto(s)
Antiinfecciosos/economía , Infecciones Comunitarias Adquiridas/tratamiento farmacológico , Infecciones Comunitarias Adquiridas/economía , Neumonía/tratamiento farmacológico , Neumonía/economía , Antiinfecciosos/uso terapéutico , Infecciones Comunitarias Adquiridas/microbiología , Femenino , Estudios de Seguimiento , Humanos , Masculino , Readmisión del Paciente , Neumonía/microbiología , Estudios Prospectivos , Resultado del Tratamiento
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