RESUMEN
As an outcome of The 2009 Nobel Prize in Physiology or Medicine, a connection has been highlighted between the length of telomeres and epigenetic effects, such as intensive changes in lifestyle and nutrition as well as behavioural and psychological factors. In this review, the various elements of molecular, cell biological, nutritional and lifestyle changes are introduced and discussed.
Asunto(s)
Epigénesis Genética , Estilo de Vida , Telomerasa/metabolismo , Acortamiento del Telómero , Telómero/metabolismo , Envejecimiento/genética , Envejecimiento/fisiología , Humanos , Leucocitos Mononucleares/citología , Leucocitos Mononucleares/enzimología , Estrés Psicológico , Telomerasa/genética , Telómero/genéticaRESUMEN
The 2009 Nobel Prize in Physiology and Medicine was awarded to three scientists for their pioneer research on telomeres - and the enzyme that forms them - telomerase. Their work highlighted the considerable connection between the length of telomeres and intensive changes in lifestyle and nutrition (Ornish method) as well as behavioral and psychological factors. In this review the various elements of molecular, cell biological, nutritional and lifestyle changes are introduced and discussed.