RESUMEN
AIM: The aim of this study was to investigate the accuracy of mandibular canine index (MCI) and mandibular mesiodistal odontometrics in sex identification in the age group of 17-25 years in central Indian population. MATERIALS AND METHODS: The study sample comprised total 300 individuals (150 males and 150 females) of an age group ranging from 17 to 25 years of central Indian population. The maximum mesiodistal diameter of mandibular canines, the linear distance between the tips of mandibular canines, was measured using digital vernier caliper on the study models. RESULTS: Overall sex could be predicted accurately in 79.66% (81.33% males and 78% females) of the population by MCI. Whereas, considering the mandibular canine width for sex identification, the overall accuracy was 75% for the right mandibular canine and 73% for the left mandibular canine observed. CONCLUSION: Sexual dimorphism of canine is population specific, and among the Indian population, MCI and mesiodistal dimension of mandibular canine can aid in sex determination.
RESUMEN
BACKGROUND: The aim of this study was to investigate the podoplanin expression in epithelial odontogenic tumors both non-aggressive and aggressive, tumors with and without ectomesenchyme and remnants of the odontogenic epithelium from dental follicles (DF) of unerupted teeth and to examine its role in progression and invasion of tumors. METHOD: Thirty paraffin embedded specimens AM (15 were non-aggressive ameloblastomas and 15 ameloblastoma showing aggressive behavior), 15 paraffin embedded specimens of AOT, 15 paraffin embedded specimens of CEOT, 15 paraffin embedded specimens of CCOT were obtained and were analyzed by immunohistochemistry using anti-human podoplanin. Podoplanin expression in odontogenic epithelial cells was evaluated using a scoring method, along with calculation of the percentage of positive odontogenic cells. RESULTS: Podoplanin was expressed strongly at the invasive front (in the peripheral odontogenic epithelial cells) of most tumors and dental follicles. Membranous expression of podoplanin in ameloblastomas was stronger in cases of ameloblastomas showing aggressive behavior than (NA) non-aggressive ameloblastomas. CONCLUSION: Expression of podoplanin at the invasive front (in peripheral cells) of odontogenic tumors considered to be associated with neoplastic odontogenic tissues. This molecule might play a role in progression and local invasion of odontogenic tumors. The migration and invasion mediated by podoplanin in odontogenic tumors could be related to cytoskeletal reorganization.
