[Role of arterio-arterial embolisms in the pathogenesis of cerebral circulatory disorders]. / Znachenie arterio-arterial'nykh émbolii v patogeneze narushenii mozgovogo krovoobrashcehniia.

The authors studied 52 patients with brain infarctions and transient disorders of cerebral circulation, which in the opinion of the authors developed as a result of arterio-arterial embolism. Besides, 16 post-mortem cases with arterio-arterial embolism were studied as well. On the basis of clinico-angiographical, clinico-laboratory and clinico-anatomical correlations, the authors come to the conclusion that this mechanism is frequently the main link in the pathogenesis of distrubed cerebral circulation. Embologenic materials in the development of brain infarctions are most often particles of parietal or obturating thrombi in the magistral cerebral vessels. In patients with transient disorders of cerebral circulation most likely embolism of the minor cerebral vessels by thrombocytic aggregates. The authors discuss the functional properties of thrombocytes in the pathogenesis of transient disorders of cerebral circulation and the feasibility of the use of antiaggregates for preventive purposes.

[Transient ischemic attacks and stroke]. / Tranzitornye ishemicheskie pristupy i mozgovoi insul't.

The authors present some results of a study of 85 patients with brain strokes which were preceded by transient cerebral ischemic attacks. In most of the cases the brain stroke developed on the background of an ischemic cardiac diabetus, atheroscleorosis of the peripheral vessels, etc. It was established that in patients with atherosclerosis, the strokes developed at earlier periods after the first ischemic attack, than in the group of patients where atherosclerosis developed in combination with arterial hypertension. In disturbance of circulation in the basin of the carotid arteries, the strokes with preceding ischemic attacks developed not only more frequently, but earlier than those due to insufficiency of the circulation in the vertebro-basillar basin. It was also established that crude focal symptomatology appears as a rule in those cases when the stroke develops after the first ischemic attack. In frequent attacks which are repeated during several years, the appearing stroke is characterized by a more light focal symptomatology.