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1.
Oncol Lett ; 28(4): 482, 2024 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-39161334

RESUMEN

The present study investigated the prognosis of patients who received palliative radiotherapy (RT) for bone metastases (BMs) from renal cell cancer (RCC), and assessed the prognostic factors specific to BMs from RCC. A total of 109 patients with RCC and BMs who underwent RT for the first time were included in the study. Prognostic factors were evaluated using multivariate analysis and a scoring system based on regression coefficients was devised. The median follow-up time was 9 months, and the 0.5-year overall survival (OS) rate was 73.0%. In the multivariate analysis, the significant prognostic factors were higher performance status (≥2), no control of the primary site, disseminated metastasis, lymph node metastasis and multiple BMs. A score of 1 point was assigned to each risk factor. The median OS times were 19.0 and 5.0 months in patients with a total score of ≤1 (n=49) and >1 (n=60), respectively (P<0.01). In conclusion, a comprehensive prognostic assessment using these factors may be useful for predicting the prognoses of patients with BMs from RCC. In addition, this scoring system may be useful in selecting the optimal RT dose.

2.
Fukushima J Med Sci ; 70(2): 93-98, 2024 Apr 26.
Artículo en Inglés | MEDLINE | ID: mdl-38494733

RESUMEN

Uterine leiomyomas, benign tumors common in reproductive-aged women, can display rare variants such as hydropic leiomyoma (HL), which exhibit unique histological features like zonal edema and increased vascularity. However, due to its rarity, comprehensive clinical knowledge about HL is limited. We report a case of a 49-year-old Japanese woman who was premenopausal and nulliparous, presenting with a two-year history of abdominal distension. An MRI scan revealed a 20 cm mass in the posterior part of the uterus, exhibiting characteristics suggestive of an ovarian tumor. During laparotomy, a cystic tumor connected with a swollen fibroid was found, and pathology confirmed HL. This case emphasizes that hydropic leiomyomas can mimic malignant tumors on ultrasonography due to their atypical features, necessitating additional evaluations using alternative imaging techniques or histopathological examinations for accurate diagnosis and appropriate management. The patient recovered uneventfully, broadening our understanding of HL's clinical presentation.


Asunto(s)
Leiomioma , Neoplasias Ováricas , Neoplasias Uterinas , Humanos , Femenino , Persona de Mediana Edad , Leiomioma/patología , Leiomioma/diagnóstico por imagen , Neoplasias Ováricas/patología , Neoplasias Ováricas/diagnóstico por imagen , Neoplasias Uterinas/patología , Neoplasias Uterinas/diagnóstico por imagen , Imagen por Resonancia Magnética , Diagnóstico Diferencial
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