Asunto(s)
Enfermedad de Leigh/diagnóstico , Enfermedad de Leigh/etiología , Debilidad Muscular/etiología , Enfermedad por Deficiencia del Complejo Piruvato Deshidrogenasa/complicaciones , Enfermedad por Deficiencia del Complejo Piruvato Deshidrogenasa/diagnóstico , Baclofeno/uso terapéutico , Carnitina/uso terapéutico , Preescolar , Diagnóstico Diferencial , Dieta Cetogénica/métodos , Humanos , Enfermedad de Leigh/terapia , Masculino , Relajantes Musculares Centrales/uso terapéutico , Debilidad Muscular/tratamiento farmacológico , Enfermedad por Deficiencia del Complejo Piruvato Deshidrogenasa/terapia , Ubiquinona/análogos & derivados , Ubiquinona/uso terapéutico , Vitaminas/uso terapéuticoRESUMEN
The article reviews and analyzes the different ear, nose, and throat (ENT)-related manifestations reported in coronavirus disease 2019 (COVID-19)-positive pediatric patients (age <18 years) in peer-reviewed and published literature. We searched the PubMed database using medical subject headings and associated key words, focusing on ENT symptoms in children with COVID-19. We included relevant published and peer-reviewed articles in English and excluded case reports and articles in press. There were 1,140 children positive for COVID-19 (56% boys) in the 23 studies included in this review. Although 11% of patients were asymptomatic, the most common symptoms reported were fever (48%) and cough (37%). Nasal symptoms (stuffy nose, nasal congestion, rhinorrhea) and sore throat occurred in about 22% of all patients. Otitis, dizziness, anosmia, and ageusia are hardly reported in children with COVID-19. Although fever and cough are the most common symptoms, ENT manifestations are frequently observed in pediatric patients with COVID-19. [Pediatr Ann. 2021;50(7):e277-e281.].
