1.
Org Lett
; 17(18): 4440-3, 2015 Sep 18.
Artículo
en Inglés
| MEDLINE
| ID: mdl-26331906
RESUMEN
Curcumin has been transformed to racemic curcuminoids via an azomethine ylide cycloaddition reaction using isatin/acenaphthoquinone and proline as the reagents. The products were characterized by extensive 1D/2D NMR analysis and single-crystal X-ray crystallographic studies. The enantiomers of one racemic product were separated by HPLC on a Chiralcel OD-H column and were indeed confirmed by the CD spectra of the separated enantiomers.