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Ren Fail ; 35(8): 1075-8, 2013 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-23879313

RESUMEN

Calcification of coronary vessels progresses rapidly in hemodialysis (HD) patients and comprises a strong predictor of cardiovascular events. The aim of this prospective study was to evaluate the coronary artery calcification (CAC) in patients with end stage renal disease undergoing regular HD and to determine the effect of renal transplantation (RT) in the progression of CAC, using the Agatston technique for calcium scoring. The study included 20 patients with end-stage renal disease undergoing a regular HD treatment (16 males, 4 females) 54.1 ± 9.5 years old who had just received a renal transplant and 16 more HD patients (11 males, 5 females) 54.4 ± 13.8 years old as control group. The baseline evaluation showed a very high prevalence of CAC in both groups, which was positively correlated with age (p < 0.001) and CRP (p = 0.03). The second (follow-up) evaluation showed a significant slower progression of calcification after RT. In both groups, high calcium score values in the follow-up evaluation had a strong positive correlation with baseline calcium score (p < 0.001).


Asunto(s)
Enfermedad de la Arteria Coronaria/epidemiología , Fallo Renal Crónico/complicaciones , Fallo Renal Crónico/terapia , Trasplante de Riñón , Diálisis Renal , Calcificación Vascular/epidemiología , Adulto , Anciano , Estudios de Casos y Controles , Enfermedad de la Arteria Coronaria/patología , Enfermedad de la Arteria Coronaria/prevención & control , Progresión de la Enfermedad , Femenino , Humanos , Fallo Renal Crónico/patología , Masculino , Persona de Mediana Edad , Prevalencia , Estudios Prospectivos , Calcificación Vascular/patología , Calcificación Vascular/prevención & control
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