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1.
Patterns (N Y) ; 2(7): 100271, 2021 Jul 09.
Artículo en Inglés | MEDLINE | ID: mdl-34286296

RESUMEN

Differential privacy allows quantifying privacy loss resulting from accession of sensitive personal data. Repeated accesses to underlying data incur increasing loss. Releasing data as privacy-preserving synthetic data would avoid this limitation but would leave open the problem of designing what kind of synthetic data. We propose formulating the problem of private data release through probabilistic modeling. This approach transforms the problem of designing the synthetic data into choosing a model for the data, allowing also the inclusion of prior knowledge, which improves the quality of the synthetic data. We demonstrate empirically, in an epidemiological study, that statistical discoveries can be reliably reproduced from the synthetic data. We expect the method to have broad use in creating high-quality anonymized data twins of key datasets for research.

2.
JMIR Mhealth Uhealth ; 9(7): e26540, 2021 07 12.
Artículo en Inglés | MEDLINE | ID: mdl-34255713

RESUMEN

BACKGROUND: Depression is a prevalent mental health challenge. Current depression assessment methods using self-reported and clinician-administered questionnaires have limitations. Instrumenting smartphones to passively and continuously collect moment-by-moment data sets to quantify human behaviors has the potential to augment current depression assessment methods for early diagnosis, scalable, and longitudinal monitoring of depression. OBJECTIVE: The objective of this study was to investigate the feasibility of predicting depression with human behaviors quantified from smartphone data sets, and to identify behaviors that can influence depression. METHODS: Smartphone data sets and self-reported 8-item Patient Health Questionnaire (PHQ-8) depression assessments were collected from 629 participants in an exploratory longitudinal study over an average of 22.1 days (SD 17.90; range 8-86). We quantified 22 regularity, entropy, and SD behavioral markers from the smartphone data. We explored the relationship between the behavioral features and depression using correlation and bivariate linear mixed models (LMMs). We leveraged 5 supervised machine learning (ML) algorithms with hyperparameter optimization, nested cross-validation, and imbalanced data handling to predict depression. Finally, with the permutation importance method, we identified influential behavioral markers in predicting depression. RESULTS: Of the 629 participants from at least 56 countries, 69 (10.97%) were females, 546 (86.8%) were males, and 14 (2.2%) were nonbinary. Participants' age distribution is as follows: 73/629 (11.6%) were aged between 18 and 24, 204/629 (32.4%) were aged between 25 and 34, 156/629 (24.8%) were aged between 35 and 44, 166/629 (26.4%) were aged between 45 and 64, and 30/629 (4.8%) were aged 65 years and over. Of the 1374 PHQ-8 assessments, 1143 (83.19%) responses were nondepressed scores (PHQ-8 score <10), while 231 (16.81%) were depressed scores (PHQ-8 score ≥10), as identified based on PHQ-8 cut-off. A significant positive Pearson correlation was found between screen status-normalized entropy and depression (r=0.14, P<.001). LMM demonstrates an intraclass correlation of 0.7584 and a significant positive association between screen status-normalized entropy and depression (ß=.48, P=.03). The best ML algorithms achieved the following metrics: precision, 85.55%-92.51%; recall, 92.19%-95.56%; F1, 88.73%-94.00%; area under the curve receiver operating characteristic, 94.69%-99.06%; Cohen κ, 86.61%-92.90%; and accuracy, 96.44%-98.14%. Including age group and gender as predictors improved the ML performances. Screen and internet connectivity features were the most influential in predicting depression. CONCLUSIONS: Our findings demonstrate that behavioral markers indicative of depression can be unobtrusively identified from smartphone sensors' data. Traditional assessment of depression can be augmented with behavioral markers from smartphones for depression diagnosis and monitoring.


Asunto(s)
Depresión , Teléfono Inteligente , Adolescente , Adulto , Depresión/diagnóstico , Depresión/epidemiología , Femenino , Humanos , Estudios Longitudinales , Aprendizaje Automático , Masculino , Autoinforme , Adulto Joven
3.
IEEE Internet Things J ; 8(23): 16723-16733, 2021 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-35582635

RESUMEN

The outbreak of Covid-19 changed the world as well as human behavior. In this article, we study the impact of Covid-19 on smartphone usage. We gather smartphone usage records from a global data collection platform called Carat, including the usage of mobile users in North America from November 2019 to April 2020. We then conduct the first study on the differences in smartphone usage across the outbreak of Covid-19. We discover that Covid-19 leads to a decrease in users' smartphone engagement and network switches, but an increase in WiFi usage. Also, its outbreak causes new typical diurnal patterns of both memory usage and WiFi usage. Additionally, we investigate the correlations between smartphone usage and daily confirmed cases of Covid-19. The results reveal that memory usage, WiFi usage, and network switches of smartphones have significant correlations, whose absolute values of Pearson coefficients are greater than 0.8. Moreover, smartphone usage behavior has the strongest correlation with the Covid-19 cases occurring after it, which exhibits the potential of inferring outbreak status. By conducting extensive experiments, we demonstrate that for the inference of outbreak stages, both Macro-F1 and Micro-F1 can achieve over 0.8. Our findings explore the values of smartphone usage data for fighting against the epidemic.

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