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Yeast ; 41(8): 477-485, 2024 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-38877753

RESUMEN

Cellobiose lipids are surface-active compounds or biological detergents produced by distinct Basidiomycetes yeasts, of which the most and best-described ones belong to the Ustilaginomycetes class. The molecules display slight variation in congener type, which is linked to the hydroxylation position of the long fatty acid, acetylation profile of the cellobiose unit, and presence or absence of the short fatty acid. In general, this variation is strain specific. Although cellobiose lipid biosynthesis has been described for about 11 yeast species, hitherto only two types of biosynthetic gene clusters are identified, and this for only three species. This work adds six more biosynthetic gene clusters and describes for the first time a novel type of cellobiose lipid biosynthetic cluster with a simplified architecture related to specific cellobiose lipids synthesized by Trichosporonaceae family members.


Asunto(s)
Basidiomycota , Celobiosa , Lípidos , Familia de Multigenes , Celobiosa/metabolismo , Basidiomycota/genética , Basidiomycota/metabolismo , Lípidos/biosíntesis , Vías Biosintéticas/genética
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