1.
Synthesis of intrathecal interferon in systemic lupus erythematosus with neurological complications.
Br Med J (Clin Res Ed)
; 287(6400): 1165-7, 1983 Oct 22.
Artículo
en Inglés
| MEDLINE
| ID: mdl-6414612
RESUMEN
Intrathecal synthesis of interferon in the absence of viral or bacterial infection was detected during the occurrence of neurological complications in two patients with systemic lupus erythematosus. The interferons displayed characteristics similar to those observed in the sera of patients with the disease. No interferon inducing activity was detected in the cerebrospinal fluid or serum of the two patients. These observations support the hypothesis of a localised mechanism of interferon induction in systemic lupus erythematosus which includes the interaction of lymphocytes with damaged tissues.
Asunto(s)
Enfermedades del Sistema Nervioso Central/líquido cefalorraquídeo , Interferón Tipo I/biosíntesis , Lupus Eritematoso Sistémico/líquido cefalorraquídeo , Adolescente , Enfermedades del Sistema Nervioso Central/etiología , Niño , Femenino , Humanos , Interferón Tipo I/sangre , Interferón Tipo I/líquido cefalorraquídeo , Lupus Eritematoso Sistémico/complicaciones
2.
J Pediatr
; 98(3): 503-4, 1981 Mar.
Artículo
en Inglés
| MEDLINE
| ID: mdl-6782217