[Analysis of 10 cases died from the acute infectious disease with the severe adrenalitis, necrosis and hemorrhage].

OBJECTIVE: To discuss the potential mechanisms and the role of adrenalitis with extensive hemorrhage and necrosis in acute critical infectious diseases. Methods Forensic autopsy cases from 1987 to 2007 were retrospectively analyzed. And 10 cases of them were involved in the primary and critical infection with acute inflammation, hemorrhage and necrosis of adrenal glands. Results Clinical diagnoses of 10 cases were respiratory tract infection (n=6), septic shock (n=2), acute esophagitis (n=1), and undefined causes (n=1), and the quickly aggravating conditions resulted in death ultimately. However, systematic autopsy confirmed that 7 cases died of acute lymphocytic pancarditis, 2 cases acute and lymphocytic interstitial pneumonia and 1 case epidemic cerebrospinal meningitis with septicemia. And severe complications of all cases included hemorrhagic necrotizing adrenalitis, systemic inflammatory response syndrome and multiple organ failure (MOF). Conclusions Hemorrhagic necrotizing adrenalitis should be considered as one of the important pathological changes in fatal MOF resulting from severe infection and trauma etc. More attention should be paid in clinical treatment.

[Measuring volume and density of human organs and its significance in medicine and forensic medicine: lung].

OBJECT: To obtain values of normal human lung and diffuse pathological changes, in order to provide a simple and convenient diagnostic method for measuring human visceral organs in the autopsy of pathology and forensic pathology. METHODS: The exact mass, volume and density of normal and pathological lung were synchronously measured with the intelligentized volume-densimeter made by authors. RESULTS: The date-base about the volume and density of human lung with different races were established for anatomy, anthropology and biodynamics. In two cases of over-load in circulation and water toxicosis, the severe lung edema was proved with the scale of lung density, which was atypical edema in the lung tissue. CONCLUSION: Measurement of visceral organs in the autopsy can assist to an integrative pathological diagnosis.