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Cytopathology ; 33(3): 397-401, 2022 05.
Artículo en Inglés | MEDLINE | ID: mdl-35118731

RESUMEN

Inflammatory myofibroblastic tumours (IMT) are spindle cell neoplasms most commonly seen in the lungs, with a wide variety of less common extrapulmonary sites including the mesentery, omentum, and intrabdominal sites. On cytological evaluation, these tumours can be difficult to diagnose, given the morphological mimics of other submucosal spindle cell neoplasms, which may be compounded by the relatively small amount of tissue and the uncommon nature of the diagnosis. Immunohistochemical staining and molecular studies for the ALK gene can prove useful for diagnosing this tumour. We present the cytological features of an IMT occurring in the rectum, the differential diagnoses, useful immunohistochemical staining patterns, and the additional finding of a novel ALK-fusion in this entity.


Asunto(s)
Tumores del Estroma Gastrointestinal , Granuloma de Células Plasmáticas , Neoplasias del Recto , Quinasa de Linfoma Anaplásico/genética , Tumores del Estroma Gastrointestinal/diagnóstico , Tumores del Estroma Gastrointestinal/genética , Granuloma de Células Plasmáticas/patología , Humanos , Recto/patología
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