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2.
Pediatr Blood Cancer ; 63(10): 1852-5, 2016 10.
Artículo en Inglés | MEDLINE | ID: mdl-27304608

RESUMEN

Ceftriaxone-induced immune hemolytic anemia (CIHA) is the second most common cause of drug-induced hemolytic anemia. Prompt recognition of this drug reaction is essential because brisk hemolysis can be deadly. The extent to which ceftriaxone antibodies persist after CIHA is unknown; rechallenging patients who have experienced CIHA is not recommended. We report a case of CIHA in a neurooncology patient, which is the first to show anticeftriaxone antibodies with Rh specificity and persisted for 8 months after the drug reaction. These findings have implications for understanding the mechanism of CIHA.


Asunto(s)
Anemia Hemolítica Autoinmune/inducido químicamente , Antibacterianos/efectos adversos , Neoplasias Encefálicas/inmunología , Ceftriaxona/efectos adversos , Glioma/inmunología , Anticuerpos/sangre , Ceftriaxona/inmunología , Preescolar , Femenino , Humanos
8.
Arch Dis Child ; 88(2): 160-1, 2003 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-12538325

RESUMEN

A unique presentation of perinatally acquired hepatitis C (HCV) with acute jaundice and chronic aggressive liver disease in a previously asymptomatic preadolescent is described. The difficulties in establishing the diagnosis and the importance of confirmatory testing for HCV in cryptogenic liver disease are discussed.


Asunto(s)
Hepatitis C/transmisión , Complicaciones Infecciosas del Embarazo , Enfermedad Aguda , Biopsia , Niño , Diagnóstico Diferencial , Femenino , Hepatitis C/patología , Hepatitis C Crónica/patología , Humanos , Hígado/patología , Cirrosis Hepática/patología , Masculino , Embarazo
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