1.
Chem Commun (Camb)
; 59(61): 9396-9399, 2023 Jul 27.
Artículo
en Inglés
| MEDLINE
| ID: mdl-37435713
RESUMEN
A novel method for synthesis of medium sized ring azasultams was proposed. It includes reductive cleavage with sodium cyanoborohydride of annulated 5,6-dihydro-2H-1,2,4-thiadiazine-1,1-dioxides that were prepared in bulk quantities by an improved procedure consisting of reacting cyclic imidates with taurine followed by treatment with phosphorus oxychloride in the presence of DIPEA.