The concentration of pesticides in onion samples from Iran: a non-carcinogenic health risk assessment.

Pesticide residues were extracted using the QuEChERS method, followed by detection by ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS). The non-carcinogenic health risk in adult and child consumers was calculated by target hazard quotient (THQ) and total target hazard quotient (TTHQ) in the Monte Carlo Simulation (MCS) method. The rank order of pesticides detected by UHPLC-MS/MS based on median concentration in onion was tebuconazole (0.004551 mg/kg) > imidacloprid (0.00233 mg/kg) > boscalid (0.00211 mg/kg) > diazinon (0.00079 mg/kg) > thiabendazole (0.00075 mg/kg) > acetamiprid (0.00052 mg/kg) > thiophanate-methyl (0.00052 mg/kg) > dichlorvos (0.000349 mg/kg) > fenitrothion (0.000132 mg/kg) > penconazole (0.00005 mg/kg). The median of TTHQ in adults and children's consumers were 4.00E-3 and 2.00E-2, respectively. TTHQ in adults and children's consumers was lower than 1 value. Hence, consumers were in the acceptable range (TTHQ <1). Consequently, onion consumption cannot endanger consumers' health status due to the pesticide residues.

Concentration of Tetrabromobisphenol-A in fish: systematic review and meta-analysis and probabilistic health risk assessment.

Tetrabromobisphenol A (TBBP-A) is an emerging pollutant that enters water resources and affects various marine organisms, such as fish. Consequently, numerous studies globally investigated TBBP-A concentrations in fish fillets of the current study were meta-analyze concentration of TBBP-A in fish fillets and estimate the associated health risks for consumers. The search encompassed international databases, including Science Direct, PubMed, Scopus, Embase, and Web of Science from January 1, 2005, to July 20, 2023. The ranking of countries based on the pooled (Mean) concentration of TBBP-A in fish was as follows: China (1.157 µg/kg-ww) > Czech Republic (1.027 µg/kg-ww) > France (0.500 µg/kg-ww) ∼ Switzerland (0.500 µg/kg-ww) > Netherlands (0.405 µg/kg-ww) > Germany (0.33 µg/kg-ww) > Sweden (0.165 µg/kg-ww)>UK (0.078 µg/kg-ww) > Belgium (0.065 µg/kg-ww) > South Korea (0.013 µg/kg-ww) ∼ Japan (0.013 µg/kg-ww) > Ireland (0.005 µg/kg-ww). The risk assessment showed that the carcinogenic and non-carcinogenic risks of TBBP-A in China and France are higher compared to other countries; however, within all countries, these risks were found to be within acceptable limits.

Concentration of potentially toxic elements in fillet shrimps of Mediterranean Sea: Systematic review, meta-analysis and health risk assessment.

In this study, an attempt was made to meta-analyzed the concentration of potentially toxic elements (PTEs) in shrimps tissue of Mediterranean Sea and health risk of consumers was estimated. Search was conducted in international databases includes Scopus, PubMed, Embase, Science Direct and Web of Science from 1 January 2010 to 20 July 2023. The random effects model used to meta-analysis of concentration of PTEs in shrimp in subgroups. In addition, non-carcinogenic and carcinogenic risks for adults and children were calculated using target hazard quotient (THQ) and cancer risk (CR). Meta-analysis concentration of PTEs in shrimps was conducted using random effects model based on country subgroups. The rank order of PTEs based on mean (pooled) level in fillet of shrimps was Fe (15.395 mg/kg-ww) > Zn (10.428 mg/kg-ww) > Cu (6.941 mg/kg-ww) Pb (5.7 mg/kg-ww) > Ni (1.115 mg/kg-ww) > As (0.681 mg/kg-ww) > Cd (0.412 mg/kg-ww) > Hg (0.300 mg/kg-ww). THQ level in adults and children due to Cd and Pb in Italy was higher than 1 value. THQ level in adults and children due to Cu, Ni, Fe, Zn and inorganic As was lower than 1 value. CR due to inorganic As in Greece and Türkiye for adults and children was higher than 1E-6 value. Therefore, it was recommended to continuously monitor and reduce the concentration of PTEs in shrimps in Italy, Greece and Türkiye, especially.

Concentration of Heavy Metals in Traditional and Industrial Fruit Juices from Iran: Probabilistic Risk Assessment Study.

Exposure to heavy metals can endanger the health of exposed people in the long term. The consumption of fruit juice is increasing; it is important to estimate the health risk of consumers due to heavy metals. The current study was carried out for the analysis of toxic metals (lead (Pb), arsenic (As), and cadmium (Cd)) and essential elements (copper (Cu) and zinc (Zn)) in 60 samples of traditional and industrial fruit juices (10 samples of different brands of apple, orange, grape, peach, mango, and pineapple) in Hamadan, West Iran, using inductivity coupled plasma optical emission spectrometry (ICP-OES) method. The validation protocol included precision of the analytical method; recovery, the determination of the limit of detection (LOD), the limit of quantification (LOQ), and linearity were measured. Moreover, risk assessment was detected using target hazard quotient (THQ) and cancer risk (CR) by the Monte Carlo simulation (MCS) model. The ranking of metal concentration in traditional and industrial fruit juices was Zn > Cu > As > Pb > Cd. In all samples, concentrations of heavy metals in industrial fruit juices were higher than traditional fruit juices p < < 0.001. The level of metals in all samples was lower of the US Environmental Protection Agency (USEPA), the World Health Organization (WHO), and the Iran Standard (IS) permissible limit set for drinking water. In terms of non-carcinogenic, values of toxic elements for children and adult in traditional and industrial fruit juices were 1.6E-3 and 1.72E-3 and 2.6E-3 and 1.85E-3, respectively. The 95th percentile of CR in adults and children due to both industrial and traditional fruits juices was higher than 1E-6; hence, reducing the concentration of As in fruit juices should be conducted. Consumption of fruit juice can increase carcinogenic risk of consumers. Therefore, it is recommended to consume it with caution.

A probabilistic health risk assessment of potentially toxic elements in edible vegetable oils consumed in Hamadan, Iran.

In this study, potential toxic element (PTEs) including lead (Pb), arsenic (As), cadmium(Cd), iron (Fe) and zinc (Zn) in traditional and industrial edible vegetable oils (peanut, sunflower, olive and sesame) collected from Hamadan, west of Iran were determined using Inductivity Coupled Plasma Optical Emission Spectrometry (ICP-OES). Besides, probabilistic health risk assessment (non-carcinogenic and carcinogenic risks) was identified via total target hazard quotient (TTHQ) and cancer risk (CR) by the Monte Carlo Simulation (MCS) model. The ranking of concentration PTEs in traditional and industrial edible vegetable oils was Fe > Zn > As > Pb > Cd. The in all samples, content of PTEs in industrial oils were upper than traditional oils (p < 0.001). The level of PTEs in most of vegetable oils was lower than permissible concentration regulated by Codex and national standard. In term of non-carcinogenic, consumers were at acceptable range (TTHQ < 1) due to ingestion both traditional and industrial vegetable oils content of PTEs. In term of carcinogenic, CR the both adults and children was higher than acceptable range (CR < 1E-6), Hence consumer are at unacceptable risk due to ingestion industrial vegetable oils content of inorganic As. Therefore, it is recommended to implement control plans for PTEs in vegetable oils consumed in Hamadan, Iran.

Exploring global mothers' knowledge, attitudes, and practice of complementary feeding: A scoping review.

Complementary feeding refers to the practice of providing solid foods and liquids in addition to breast milk when a baby reaches 6 mo of age. This becomes necessary to meet a baby's nutritional needs because of the potential nutrient insufficiency of breast milk alone. This review serves as an effective means to comprehensively understand the intricate and evolving nature of complementary feeding practices, often influenced by cultural, regional, and parental factors, from a literature perspective that acknowledges the dynamic aspects of complementary feeding. The data in this study were extracted and presented according to the recommendations from the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for scoping reviews, as guidelines. The studies were conducted using digital databases such as PubMed, Springer Link, and Science Direct from 2014 to 2022. A total of 1205 eligible studies were retrieved from the three databases searched, with 17 articles finally reviewed for data extraction. Overall, there remains a gap between mothers' knowledge, attitudes, and practices regarding complementary feeding. Addressing these disparities within and between countries necessitates targeted interventions and educational programs to enhance mothers' understanding, align attitudes with guidelines, and promote healthier practices for the well-being of children.

Potentially toxic elements (PTEs) in coastal sediments of Bandar Abbas city, North of Persian Gulf: An ecological risk assessment.

The concentration of potentially toxic elements (PTEs; Lead (Pb), Nickel (Ni), and Cadmium (Cd) Pb, Ni, and Cd), using flame atomic absorption spectrometry (FAAS) was measured in fifty surface coastal sediment samples collected from 5 points coastal sediment of Bandar Abbas city, Iran besides the potential ecological risk index (RI) estimated the environmental health risk. The rank order of PTEs was Pb (52.090 ± 4.113 mg/kg dry weight) > Ni (34.940 ± 8.344 mg/kg dry weight) > Cd (2.944 ± 0.013 mg/kg dry weight). RI due to PTEs in sediments for A, B, C, D, and E points were 187.655, 190.542, 191.079, 189.496, and 192.053, respectively. RI for sampling points A to E was at moderate risk (150 ≤ RI < 300). Therefore, it is recommended to carry out control programs to reduce the amount of PTEs in the coastal sediment of the Persian Gulf.

The concentration of radioisotopes (Potassium-40, Polonium-210, Radium-226, and Thorium-230) in fillet tissue carp fishes: A systematic review and probabilistic exposure assessment.

Chemical contamination of seafood has become a global health concern. Carp fish is one of the most widely consumed globally, and several studies have been conducted on the contamination of carp fish with radioisotopes. In the current study, a meta-analysis and probabilistic exposure assessment regarding the Potassium-40 (40K), Polonium-210 (210Po), Radium-226 (226Ra), and Thorium-230 (230Th) in the fillet tissue of carp fish were performed. In this regard, Scopus and PubMed were screened to retrieve the associated citations with on the concentration of radioisotopes in the fillet tissue of carp fish until October 2021. The rank order of radioisotopes in fillet tissue carp fish was 40K (103.49 Bq kg-1) > 210Po (9.39 Bq kg-1) > 226Ra (0.62 Bq kg-1) > 230Th (0.39 Bq kg-1). The highest effective dose due to 210Po ingestion was observed in Spain (male; 4.44E-05 Sv y-1, female; 2.67E-06 Sv y-1); 40K (female, 5.07E-07 Sv y-1); 226Ra (male, 9.93E-09 Sv y-1). The mean of effective dose (ED) in the male and females in India due to ingestion of 230Th as result of carp fish consumption was (1.70E-06 Sv y-1) and (7.01E-08 Sv y-1), respectively. The probabilistic exposure assessment by the Monte Carlo simulation method revealed that consumers of fillet tissue carp fish content of radioisotopes are at a safe range (0.001 Sv y-1).

The concentration of Potentially Toxic elements (PTEs) in the muscle of crabs: a global systematic review, meta-analysis, and health risk assessment.

The concentration of PTEs in the muscle of crabs, was meta-analyzed using a random-effects model based on countries' subgroups. The non-carcinogenic and carcinogenic risks related to the ingestion of PTEs via the consumption of crab fish were estimated. The meta-analysis included one hundred and eight papers with 109 data reports. The rank order of PTEs based on pooled (mean) concentration in the muscle of crabs was Ni (4.490 mg/kg-ww) > Pb (1.891 mg/kg-ww) >As (1.601 mg/kg-ww) > Cd (1.101 mg/kg-ww). The results showed that adults and children consumers in many countries are at risk of non-carcinogenicity due to ingestion of Ni, Pb, As, and Cd and carcinogenicity risk due to As. Therefore, the bioaccumulation of PTEs in the muscle of crabs can be considered a global health risk. Hence, to decrease the health risk of PTEs in the muscle of crabs, continuous monitoring and reducing the emission of PTEs in aquatic environments are recommended.

Concentration and non-dietary human health risk assessment of pesticide residues in soil of farms in Golestan province, Iran.

Detection of pesticide residues in soil samples was conducted using UHPLC-MS/MS. Non-dietary health risk assessment was conducted using calculate chronic daily intake (CDI) from ingestion, inhalation and dermal contact pathways and following non-carcinogenic and carcinogenic risks in the adults and adolescent. The rank order of pesticide in soil based on their concentration was malathion (0.082 mg kg-1)> cyproconazole (0.019 mg kg-1)> propargite (0.018 mg kg-1)> butachlor (0.016 mg kg-1) > chlorpyrifos (0.0067 mg kg-1)> diazinon (0.0014 mg kg-1)> imidacloprid (0.0007 mg kg-1). Hazard index (HI) values obtained of exposure to pesticides in soil in adults and adolescent were 0.0012 and 0.0035, respectively. Hence, exposed population are at the acceptable range of non-carcinogenic risk (HI < 1). Cancer risk (CR) values due to propargite in soil via ingestion pathway in adults and adolescent were 2.03E-09 and 2.08E-09, respectively; therefore, carcinogenic risk due to the exposure to pesticide contaminated soil was safe range (CR < 1E-06).

Study on the role of nano antibacterial materials in orthodontics (a review)

Abstract Nanoparticles (NPs) are insoluble particles with a diameter of fewer than 100 nanometers. Two main methods have been utilized in orthodontic therapy to avoid microbial adherence or enamel demineralization. Certain NPs are included in orthodontic adhesives or acrylic resins (fluorohydroxyapatite, fluorapatite, hydroxyapatite, SiO2, TiO2, silver, nanofillers), and NPs (i.e., a thin layer of nitrogen-doped TiO2 on the bracket surfaces) are coated on the surfaces of orthodontic equipment. Although using NPs in orthodontics may open up modern facilities, prior research looked at antibacterial or physical characteristics for a limited period of time, ranging from one day to several weeks, and the limits of in vitro studies must be understood. The long-term effectiveness of nanotechnology-based orthodontic materials has not yet been conclusively confirmed and needs further study, as well as potential safety concerns (toxic effects) associated with NP size.

Resumo Nanopartículas (NPs) são partículas insolúveis com diâmetro inferior a 100 nanômetros. Dois métodos principais têm sido utilizados na terapia ortodôntica para evitar a aderência microbiana ou a desmineralização do esmalte: NPs são incluídas em adesivos ortodônticos ou resinas acrílicas (fluoro-hidroxiapatita, fluorapatita, hidroxiapatita, SiO2, TiO2, prata, nanopreenchimentos) e NPs são revestidas nas superfícies de equipamentos ortodônticos, ou seja, uma camada fina de TiO2 dopado com nitrogênio nas superfícies do braquete. Embora o uso de NPs em ortodontia possa tornar acessível modernos recursos, pesquisas anteriores analisaram as características antibacterianas ou físicas por um período limitado de tempo, variando de 24 horas a várias semanas, por isso devem ser compreendidos os limites dos estudos in vitro. A eficácia de longo prazo de materiais ortodônticos com base em nanotecnologia ainda não foi confirmada de forma conclusiva, o que exige mais estudos, bem como potenciais preocupações de segurança (efeitos tóxicos) associadas ao tamanho da NP.

Study on the role of nano antibacterial materials in orthodontics (a review) / Estudo sobre o papel dos materiais nanoantibacterianos na ortodontia

Nanoparticles (NPs) are insoluble particles with a diameter of fewer than 100 nanometers. Two main methods have been utilized in orthodontic therapy to avoid microbial adherence or enamel demineralization. Certain NPs are included in orthodontic adhesives or acrylic resins (fluorohydroxyapatite, fluorapatite, hydroxyapatite, SiO2, TiO2, silver, nanofillers), and NPs (i.e., a thin layer of nitrogen-doped TiO2 on the bracket surfaces) are coated on the surfaces of orthodontic equipment. Although using NPs in orthodontics may open up modern facilities, prior research looked at antibacterial or physical characteristics for a limited period of time, ranging from one day to several weeks, and the limits of in vitro studies must be understood. The long-term effectiveness of nanotechnology-based orthodontic materials has not yet been conclusively confirmed and needs further study, as well as potential safety concerns (toxic effects) associated with NP size.

Nanopartículas (NPs) são partículas insolúveis com diâmetro inferior a 100 nanômetros. Dois métodos principais têm sido utilizados na terapia ortodôntica para evitar a aderência microbiana ou a desmineralização do esmalte: NPs são incluídas em adesivos ortodônticos ou resinas acrílicas (fluoro-hidroxiapatita, fluorapatita, hidroxiapatita, SiO2, TiO2, prata, nanopreenchimentos) e NPs são revestidas nas superfícies de equipamentos ortodônticos, ou seja, uma camada fina de TiO2 dopado com nitrogênio nas superfícies do braquete. Embora o uso de NPs em ortodontia possa tornar acessível modernos recursos, pesquisas anteriores analisaram as características antibacterianas ou físicas por um período limitado de tempo, variando de 24 horas a várias semanas, por isso devem ser compreendidos os limites dos estudos in vitro. A eficácia de longo prazo de materiais ortodônticos com base em nanotecnologia ainda não foi confirmada de forma conclusiva, o que exige mais estudos, bem como potenciais preocupações de segurança (efeitos tóxicos) associadas ao tamanho da NP.

Prevalence and concentration of aflatoxin M1 and ochratoxin A in cheese: a global systematic review and meta-analysis and probabilistic risk assessment.

Exposure to mycotoxins such as aflatoxins can endanger human health, especially infants and children. In this study, an attempt was made to retrieved studies related to the concentration of aflatoxin M1 (AFM1) and ochratoxin A (OTA). Search was performed in international databases such as Embase, PubMed, Scopus, and Web of Science for the period 1 January 2010 to 20 February 2023. Then, the pooled concentration in the defined subgroups was calculated using meta-analysis and the health risk assessment was conducted by margin of exposure (MOEs). Thirty-one scientific papers with 34 data reports (Sample size=2,277) were included in our study. The lowest and highest prevalence of AFM1 in cheese was related to El Salvador (12.18 %) and Serbia (100.00 %). The pooled prevalence of AFM1 was 49.85 %, 95 %CI (37.93-61.78 %). The lowest and highest prevalence of OTA in cheese was related to Türkiye (6.67 %) and Italy (44.21 %). The pooled prevalence of OTA was 35.64 %, 95 %CI (17.16-56.44 %). Health risk of AFM1 revealed that except Pakistan and Iran, MOE in the other countries was lower than 10,000 for adults and also except Pakistan, MOE for other countries was lower than 10,000 for children. Health risk of OTA revealed that except Greece, MOE in the other countries was higher than 10,000 for adults and also except Germany and Greece, MOE for other countries was higher than 10,000 for children. Therefore, it is recommended to conduct control plans to reduce the concentration of mycotoxins in cheese, especially AFM1.

Concentration of potential toxic elements in canned tuna fish: systematic review and health risk assessment.

The health risks (non-carcinogenic and carcinogenic risk) were calculated in both adults and children, using target hazard quotient (THQ) and carcinogenic risk (CR). The concentrations of Cd, Pb, and Ni were higher than the standard limits but they did not pose any non-carcinogenic health risks in adult and children's consumers (THQ <1). Meanwhile, the risk assessment of iAs indicates THQ > 1 for children in Egypt. Moreover, the THQ value due to Me Hg for adult in Tunisia and for children in Tunisia, Malta, Portugal, Latvia, Cambogia, Peru, South Korea, Romania, Hong Kong, United Arab Emirates, Morocco, and Egypt was higher than 1 value. In addition, the calculated CR values of iAs for the adults and children were within the threshold risk of developing cancer (Between 1.00E-4 to 1.00E-6). Therefore, it is recommended to continuously monitor the concentration of PTEs in canned tuna.

Preliminary Study: The Effectiveness of Nutrition Education Intervention Targeting Short-Statured Pregnant Women to Prevent Gestational Stunting.

A short mother with a height < 150 cm is likely to give birth to a short baby with a body length < 48 cm so that later this short baby will become stunted. The success rate of stunting malnutrition prevention and control with specific methods is 30% and the success rate with sensitive methods is 70%. The size at risk for short pregnant women is equal to 30.5%. A major effort to improve the health status of short pregnant women and prevent stunting is to empower short pregnant women with the help of health professionals. This study aimed to analyze the effectiveness of providing nutrition education to pregnant women who have short stature to prevent gestational stunting. This study used a quantitative approach with a quasi-experimental design in the intervention group and the control group. Research results showed that there are differences in the knowledge, attitudes, and actions of pregnant women about prenatal care services before and after the intervention, as well as knowledge of pregnant women about nutrition before and after intervention. The support of the cadres had a great influence on the intervention group compared with the control group, which received only one module. Pregnant women's knowledge of nutritional diets and pregnant women's knowledge of antenatal care (ANC) services directly influence the delivery timing. Interventions to improve the health status of short pregnant women and prevent stunting neonates can be improved by improving the knowledge, attitudes, and behavior of short pregnant women about antenatal care, and knowledge of pregnant women about nutritional intake. The Short Pregnancy Medical Framework Support Model was developed for use in providing support to short pregnant women to prevent infant stunting.

The concentration of pesticides in tomato: a global systematic review, meta-analysis, and health risk assessment.

To improve farming productivity, a large number of pesticides have been used worldwide in recent decades, leading to the pollution of soil, agri-products, and water, directly/indirectly affecting human health. In this regard, many studies were conducted in different countries on residual pesticides in the environment. In the current study, residual pesticides including chlorpyrifos, cypermethrin, diazinon, malathion, and metalaxyl in tomatoes were meta-analyzed and health risk of consumers was estimated. For this purpose, based on a systematic review, data from 47 studies were extracted and meta-analyzed, and the health impact of pooled concentrations was assessed via a health risk method. According to the results, metalaxyl had the most concentration followed by malathion, cypermethrin, diazinon, and chlorpyrifos, respectively. The non-carcinogenic risk (n-CR) was calculated from crop consumption also showed that exposure to malathion has the most risk. Among the investigated communities, Iranian consumers were in considerable health risk (THQ > 1). Considering that the potential for the use of pesticides will increase with the need for food in the future, hence, governments must manage the usage by governments via alternative methods such as cultural, biological, physical, and genetic modifications.

Concentration ciguatoxins in fillet of fish: A global systematic review and meta-analysis.

In the current study, an attempt was made to meta-analyze and discuss the concentration of ciguatoxins (CTXs) in fillets of fish based on country and water resources subgroups. The search was conducted in Scopus and PubMed, Embase and Web of Science to retrieve papers about the concentration of CTXs in fillet fish until July 2022. Meta-analysis concentration of CTXs was conducted based on countries and water resources subgroups in the random effects model (REM). The sort of countries based on the pooled concentration of CTXs was Kiribati (3.904 µg/kg) > Vietnam (1.880 µg/kg) > Macaronesia (1.400 µg/kg) > French (1.261 µg/kg) > China (0.674 µg/kg) > Japan (0.572 µg/kg) > USA (0.463 µg/kg) > Spain (0.224 µg/kg) > UK (0.170 µg/kg) > Fiji (0.162 µg/kg) > Mexico (0.150 µg/kg) > Australia (0.138 µg/kg) > Portugal (0.011 µg/kg). CTXs concentrations in all countries are higher than the safe limits of CTX1C (0.1 µg/kg). However, based on the safe limits of CTX1P, the concentrations of CTXs in just Portugal meet the regulation level (0.01 µg/kg). The minimum and maximum concentrations of CTXs were as observed in Selvagens Islands (0.011 µg/kg) and St Barthelemy (7.875 µg/kg) respectively. CTXs concentrations in all water resources are higher than safe limits of CTX1C (0.1 µg/kg) and CTX1B (0.01 µg/kg). Therefore, it is recommended to carry out continuous control pans of CTXs concentration in fish in different countries and water sources.

Residues of carcinogenic pesticides in food: a systematic review.

Most agricultural products are exposed to pesticides. Organochlorine (OCPs) insecticides have been banned for years due to their persistence in the environment and lipophilic properties. On the other hand, some carcinogenic organophosphates are used in high amounts. Therefore, this systematic review was performed with the keywords; pesticide, carcinogenic, carcinogen, residue, contamination, pollution, and food to determine the type of food and pesticide. 663 manuscripts were found by searching in databases. After initial screening and quality assessment of full text, 26 manuscripts were selected. In this study, by reviewing selected manuscripts, about 13 pesticides were associated with carcinogenic effects. These pesticides were Chlorothalonil, Glyphosate, Tetrachlorvinphos, Parathion, Malathion, Diazinon, heptachlor, Hexachlorobenzene, aldrin, dieldrin, DDT, chlordane, Lindane. Most of these pesticides were organochlorine. The organochlorine pesticides are primarily detected in foods of animal origin. In some studies, the amount of carcinogenic organochlorine was higher than the permissible levels. From the carcinogenic herbicide, Glyphosate. An important finding of this systematic review is that carcinogenic organochlorines are still a threat to cancer incidence.

A systematic review of the relationship between household food insecurity and childhood undernutrition.

BACKGROUND: This systematic review aims to investigate the association between household food insecurity (HFIS) and undernutrition in children under 5 years old, thereby informing policymakers on the vital factors needed to be considered in tailoring an effective strategy to tackle childhood undernutrition and ultimately HFIS. METHODS: We performed a systematic review that examined household food insecurity among the undernourished under-five children. PubMed, Cochrane, EBSCO Host, Web of Science and Cumulative Index to Nursing and Allied Health Literature were searched from 1 January 2012 to 1 April 2022, for relevant articles. Outcome measures were stunting, underweight or wasting. Of the 2779 abstracts screened, 36 studies that fulfilled the inclusion and exclusion criteria were included. A range of tools had been used to measure HFIS, the most common being Household Food Insecurity Access Scale. HFIS has been found to be significantly associated with undernutrition, particularly stunting and underweight. This is observed proportionately across all national income levels. CONCLUSIONS: Sustainable and inclusive economic growth, which aims to reduce income, education and gender inequality, should be a key policy goal in the minimizing food insecurity and childhood undernutrition. Multisectoral interventions are needed to address these issues.

Effectiveness of Food-Based Intervention to Improve the Linear Growth of Children under Five: A Systematic Review and Meta-Analysis.

Food-based interventions to improve linear growth are most often applied in low- and middle-income countries. However, not all food interventions have been proven to be effective in promoting linear growth. This study aimed to assess the impact and effectiveness of food interventions for improving linear growth in children under five years old. This study was conducted by following the PRISMA guidelines and the data were extracted and presented following the PRISMA recommendations. Studies were identified through a literature search of the SCOPUS, Web of Science, PubMed, ScienceDirect, and ProQuest databases from 2000 to 2022. Only randomized control studies were included in this review based on the inclusion and exclusion criteria. Out of 1125 studies identified, a total of 15 studies were included in this systematic review and meta-analysis. The review result indicated that food-based intervention can help to improve linear growth (MD: 0.20, 95% CI: 0.04 to 0.35, p = 0.01) among children under five. However, there was no significant difference in changes in underweight status (MD: 0.25; CI: -0.15 to 0.64; p = 0.22) and wasting status (MD: 0.09; CI: -0.02 to 0.20; p = 0.12) between the intervention and control groups. Overall, food-based interventions were found to be helpful for improving children's linear growth.