Potency of Pfeiffer's Crystallization to Analyze Oral Leukoplakia and Squamous Cell Carcinoma.

OBJECTIVE: Oral cancer usually has an early precancerous stage before its actual malignant transformation. Although there are various approaches to diagnose early stages of cancer, yet there is one less explored, cost effective and simple technique known as crystallization test. The aim of the study was to reaffirm the effectiveness of Pfeiffer's crystallization test in screening oral leukoplakia and squamous cell carcinoma. METHODS: Fifty oral leukoplakia, sixty five oral squamous cell carcinoma and sixty healthy individuals participated in crystallization test. Single blood drop was used to perform the test and obtained crystal patterns were analysed. Cross tabulation and Chi-Square test was performed to find the frequency and association between the groups. Kruskal-Wallis H test and Mann Whitney U test was applied comparing mean transverse form. RESULTS: Sensitivity of crystallization test was 80% and 93.84% in oral leukoplakia and squamous cell carcinoma. Chi-Square analysis revealed highly significant transverse form between the study groups (p < 0.000). CONCLUSION: Crystallization test proves to be simple, reliable and minimal invasive diagnostic approach under strictly maintained physical conditions.

Baseline data of facial parameters in the population of Haryana: An anthropometric study.

CONTEXT: Anthropometry plays an important role in the assessment of ethnicity and identification of an individual. There is paucity of literature on various facial parameters in Haryanvi population. Thus, the present study was an initiation to collect this database in Haryanvi population. AIM: The aim of the present study was to create a database of craniofacial parameters of Haryanvi population. MATERIALS AND METHODS: The study was conducted on 300 individuals of Haryanvi ethnicity. A digital vernier caliper was used for the measurement of facial parameters. STATISTICAL ANALYSIS: Chi-square test, t-test, and Pearson's correlation test were used for finding the difference between the measurements for various parameters. RESULTS: In the present study, mesoprosopic was the predominant facial phenotype in both males and females. A significant sexual dimorphism was found between all the facial parameters measured in the study. However, upper facial height and facial index did not follow the same pattern in relation to gender determination. CONCLUSION: Based on the present study findings, we conclude that craniofacial parameters could be used as an important tool to assess the ethnicity and gender of an individual. In addition, our data could be used as a baseline for further studies in the identification of a Haryanvi individual.

Convolutions of dentigerous cyst: An institutional experience.

OBJECTIVE: Statement of the Problem: Benign appearing dentigerous cyst (DC), also the most common developmental odontogenic cyst, shows various complications due to its pluripotent cell lining. The spectrum of diseases produced by conversion of its pluripotent cell varies from unicystic ameloblastoma, intraosseous epidermoid and central mucoepidermoid carcinoma. So, the need of the hour is to be acquainted with the etiopathogenesis of DC at molecular level and an attempt should be made to minimize its rate of tumor conversion. PURPOSE: To analyze the potential complications, their demographic profile, disease characteristics which can arise from the dentigerous cyst, and to be geared up for such situations in future. MATERIALS AND METHOD: Retrospective analysis was conducted and data was collected from the requisition forms during the time frame 2011- 2016 in the Department at Government Dental College, Haryana. Histopathologically diagnosed cases of dentigerous cyst were reviewed by three different observers and recorded, out of which DCs that showed potential complications were reviewed in detail. RESULTS: Six cases of DC out of 26 showed transformation into central mucoepidermoid carcinoma, adenomatoid odontogenic tumor (two) and ameloblastoma (three) respectively. CONCLUSION: The present research highlights the probable complications of DC encountered in our institute and conscientious vigilance should be exercised while histopathological examination of biopsied specimens. This study further unravels the enigma behind the emergence of neoplasms arising from DC.