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Expert Rev Anticancer Ther ; 13(7): 861-70, 2013 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-23875664

RESUMEN

The status of regional lymph nodes is the most important prognostic factor in early cervical cancer patients. Pelvic lymph node dissections are routinely performed as a part of standard surgical treatment. Systematic pelvic lymphadenectomy is associated with short- and long-term morbidities. This review discusses single components of the sentinel lymph node mapping (SLNM) technique and results of the detection of sentinel lymph nodes. SLNM biopsy performed by an experienced team for small volume tumors (<2 cm) has high specific side detection rate, excellent negative-predictive value and high sensitivity. Uncommon lymphatic drainage has been reported in 15% of cervical cancer patients. There is sufficient data now to suggest that SLNM with 99mTc plus blue dye in the hands of a surgeon with extensive experience should prove to be an important part of individualized cervical cancer surgery and increase the safety of less radical or fertility-sparing surgery.


Asunto(s)
Biopsia del Ganglio Linfático Centinela/métodos , Neoplasias del Cuello Uterino/patología , Femenino , Humanos , Escisión del Ganglio Linfático , Metástasis Linfática , Valor Predictivo de las Pruebas , Pronóstico , Sensibilidad y Especificidad , Tecnecio , Factores de Tiempo , Neoplasias del Cuello Uterino/terapia
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