RESUMEN
Workers engaged in the production of inorganic manganese salts revealed lesions of the upper respiratory pathways (catarrhal and subatrophic rhinitis, pharyngitis, laryngitis), skin (contact and allergic dermatitis), cardiovascular disorders. They also showed changes of renal function,mineral metabolism,acid stability of erythrocytes. Activation of the B-system of immunity and allergization of the body are also observed.
Asunto(s)
Industria Química , Estado de Salud , Manganeso/efectos adversos , Exposición Profesional/efectos adversos , Adulto , Contaminantes Ocupacionales del Aire/efectos adversos , Dermatitis Profesional/inducido químicamente , Dermatitis Profesional/diagnóstico , Dermatitis Profesional/epidemiología , Femenino , Humanos , Masculino , Enfermedades Profesionales/inducido químicamente , Enfermedades Profesionales/diagnóstico , Enfermedades Profesionales/epidemiología , Exposición Profesional/estadística & datos numéricos , Ucrania/epidemiologíaAsunto(s)
Detergentes/farmacología , Hígado/efectos de los fármacos , Animales , Membrana Celular/efectos de los fármacos , Membrana Celular/metabolismo , Colesterol/metabolismo , Hemólisis , Técnicas In Vitro , Peroxidación de Lípido , Hígado/metabolismo , Perfusión , Fosfolípidos/metabolismo , RatasRESUMEN
It was established that the major hazardous factor in nitrate, sulphate and manganese basic carbonate processing shops was the dust of the final product. Upper respiratory tract (catarrhal, subatrophic rhinitis, pharyngitis, laryngitis), skin (allergic and contact dermatitis) and cardiac disorders were specified as the predominant pathology among manganese compounds processing shop workers. Mineral exchange disorders, lowered glucose content in the blood and violation in the acid persistence of the erythrocytes were revealed through medical examinations.
Asunto(s)
Industria Química , Manganeso/efectos adversos , Enfermedades Profesionales/inducido químicamente , Adulto , Aberraciones Cromosómicas , Femenino , Humanos , Masculino , Enfermedades Profesionales/diagnóstico , Enfermedades Profesionales/inmunologíaAsunto(s)
Ferricianuros/toxicidad , Ferrocianuros/toxicidad , Hipercolesterolemia/inducido químicamente , Hiperpotasemia/inducido químicamente , Fosfatasa Alcalina/sangre , Animales , Nitrógeno de la Urea Sanguínea , Activación Enzimática/efectos de los fármacos , Masculino , Ratones , Ratas , Factores de TiempoRESUMEN
The perfusion in situ of the rat liver reveals appearance of enzymes of different subcellular localization, potassium ions and lipid components in the perfusate. Ethanol introduction at different doses induces the most expressed changes in the activity of catalase, lactate dehydrogenase, arginase and alanine aminotransferase and in the potassium removal from hepatocytes. A degree of the evoked changes depends on the dose.